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Junk DNA: How the dark genome is changing RNA therapies

Drug Discovery World

Samir Ounzain , PhD, CEO & Co-Founder of HAYA Therapeutics, looks at how a better understanding of our DNA can lead to increased activity for RNA therapeutics. The whole world realised the power of RNA when the Covid-19 pandemic brought us the first mRNA-based vaccines. This landscape is rapidly changing.

RNA 52
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A new dawn of the genomic age: five areas set to be transformed in 2023

pharmaphorum

Protein prediction algorithms will reach their potential Proteomics has long been hindered by inaccurate or incomplete RNA sequences – with resultant predictive models built from RNA proving inaccurate. The post A new dawn of the genomic age: five areas set to be transformed in 2023 appeared first on.

Genome 129
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Why genomic healthcare data matters in the development of new therapies 

Drug Discovery World

One might argue that this all started getting exciting with the launch of the Human Genome Project, which the National Human Genome Research Institute consider to be one of the greatest scientific feats in history 1. DDW’s Megan Thomas observes developments of accessibility in this sector and the potential impact. .

Genome 98
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Can Singapore become a global hub for biotech?

Drug Discovery World

Dr Gokhale expands on the country’s leadership role: “Singapore is a great example of integration of genomic medicine in healthcare via population scale research. The SG100K/PRECISE project is exemplar of how multi-dimensional population scale genomics projects when done right, can have a significant impact on the practice of medicine.

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Where is the drug discovery expertise happening in the UK?

Drug Discovery World

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases.

Drugs 73
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Spatial Genomics, Transcriptomics and Proteomics Solutions – An Amelioration of Tissue Analytics

Roots Analysis

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. The trend is unlikely to change in the foreseen future. Concluding Remarks.

Genome 52
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Predictive diagnostics: closing the precision medicine gap

Drug Discovery World

Both the binary and quantitative have relied on measurement of protein, DNA, and more recently, RNA. He is the founder and CEO of Cofactor Genomics, a diagnostic company leveraging the power of RNA and machine learning to build disease models.