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Scottish drug discovery: advancing new research models

Drug Discovery World

Following the Scottish Research and Drug Development Forum meeting, DDW’s Diana Spencer provides a snapshot of drug discovery in Scotland. With over 150 pharma services/supply companies and 19 universities, Scotland is one of the most advanced life science sectors in the UK and the world. There are various other phenomics projects currently ongoing.

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Genomics Market: Rising Government Expenditure in Genomics R&D to Boost the Global Market Wilmington, Delaware, United States, Transparency Market Research Inc.: The global genomics market is projected to grow at a promising rate from 2021 to 2031. In-vitro Toxicology Assays Market: Witnessing Moderate Growth during the Forecast Period [2021-2031] The global in-vitro toxicology assays market is expected to witness moderate growth during the forecast period between 2021 and 2031. Insulin Delivery Devices Market: Increase in the Prevalence Rate of Diabetes and Related Diseases Across the World to Drive the Market Wilmington, Delaware, United States, Transparency Market Research Inc.: Patient suffering from either type of diabetes mellitus require insulin to regulate adequate glucose level in the blood. Invisible Orthodontics Market: Increase in Focus on Esthetic Dentistry is Projected to Drive the Global Market Wilmington, Delaware, United States, Transparency Market Research Inc.: According to the report, the

BioSpace

Rather than selling, Novartis could spin Sandoz off into its own separate entity with its own listing on a stock exchange.

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Evotec Expands Oxfordshire Site into a Fully-Integrated R&D Centre Named ‘Dorothy Crowfoot Hodgkin Campus’

The Pharma Data

ADDS IN VITRO PHARMACOLOGY AND EXPANDS PROTEIN SCIENCES. CREATES UNIQUE CO-LOCATED, FULLY-INTEGRATED, HIGH-CAPACITY R&D CENTRE. CREATES CENTRE OF EXCELLENCE FOR STRUCTURE-BASED DRUG DESIGN. INCREASES GLOBAL CAPACITY FOR HIGH-VALUE INTEGRATED DRUG DISCOVERY AND COMMERCIAL DEVELOPMENT OFFERING.

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Biologics – The Next Step in Revolutionary Medication

Roots Analysis

Usually, the desired gene, such as human insulin gene, when inserted into the plasmid of the host cell uses transcriptional and translational machinery of the host to express itself. It is worth mentioning that in vitro gene expression requires a suitable host for the production of a specific gene product.

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Poxel Announces Additional Positive Phase 2a Results, and Phase 2b Plan for PXL770, an Oral First-in-Class AMPK Activator, in NASH

The Pharma Data

7.1%) levels were well controlled, and in this context, significant placebo-adjusted decreases were observed in both glycemic parameters along with improvements in commonly used fasting indexes of insulin sensitivity (HOMA-IR and QUICKI scores). In the T2DM patients, baseline fasting glucose (121-144 mg/dL) and HbA1c (6.6-7.1%)

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Biologic Therapeutics Development, Part 1: Definition and Distinct Characteristics

Camargo

In vitro binding assays and functional tests might be required to identify the test material which is pharmacologically active , and a potency assay is required due to the complexity and heterogeneity of biologics. Blood and blood components. Allergenics. Somatic cells. Gene and cellular therapies. Recombinant therapeutic proteins.

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Receptor Occupancy Assays by Flow Cytometry: Benefits for Clinical Trials

XTalks

Both the areas of drug development and clinical trials are increasingly using in vitro assays to help determine the efficacy of an investigational therapeutic. Flow cytometric receptor occupancy assays are being increasingly used in preclinical and clinical studies. What is Flow Cytometry?