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Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA)

Rethinking Clinical Trials

DIHI approaches this work through four pillars of innovation: implementation and health delivery science, health technology innovation, leadership and workforce development, and best practices development and dissemination. Key decision point 1 is procurement. There is a massive inequity and teams like DIHI are very rare.

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Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. Krumholz, MD, SM)

Rethinking Clinical Trials

PaxLC brings together many innovations including online screening, digital medical record review, e-consent, home-delivery of medications, local clinical blood draws, home-based biospecimen collection, online diaries and surveys, digital medical record outcomes, and participant-centricity, and return of results.

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Grand Rounds January 20, 2023: Collaborative Pragmatic Trials in Action: EVOLVE-MI (Mikhail Kosiborod, MD)

Rethinking Clinical Trials

EVOLVE-MI has trial innovation through its Academic Research Organizations (AROs), who are also enrolling and understand challenges firsthand. EVOLVE-MI has trial design and infrastructure innovations, including automated data collection and leveraging Swedish registries.

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Expert LinkedIn Tips and Tricks for the Pharmaceutical Industry 

Pharma Marketing Network

Use keywords: When you’re filling out your profile, be sure to use relevant keywords throughout. Some relevant groups to join include: Pharmaceutical Research and Manufacturers of America (PhRMA), Biotechnology Innovation Organization (BIO), and American Society of Clinical Oncology (ASCO).

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Grand Rounds August 18, 2023: Opportunities to Improve Clinical Trials: Draft Revision of the ICH Good Clinical Practice Guideline (E6R3) (Prof Sir Martin Landray, FMedSci; M. Khair ElZarrad, PhD, MPH)

Rethinking Clinical Trials

Food and Drug Administration (FDA) Slides Keywords Pragmatic trials; Research; Guidance, Regulatory, Data Governance Key Points The clinical trial enterprise needs modernization. The scope is focused, and the language aims to facilitate innovation in trial design.

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Grand Rounds August 18, 2023: Opportunities to Improve Clinical Trials: Draft Revision of the ICH Good Clinical Practice Guideline (E6R3) (Prof Sir Martin Landray, FMedSci; M. Khair ElZarrad, PhD, MPH; Adrian F. Hernandez, MD, MHS)

Rethinking Clinical Trials

Food and Drug Administration (FDA) Slides Keywords Pragmatic trials; Research; Guidance, Regulatory, Data Governance Key Points The clinical trial enterprise needs modernization. The scope is focused, and the language aims to facilitate innovation in trial design.

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Novel method predicts if COVID-19 clinical trials will fail or succeed

Bioengineer

The study, published in PLOS ONE , provides the most extensive set of features for clinical trial reports, including features to model trial administration, study information and design, eligibility, keywords, drugs and other features. In total, 693 dimensional features were created to represent each clinical trial.