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Yale-NBA Partnership Results in FDA Approval for COVID-19 SalivaDirect Test

XTalks

An important feature of the test that contributes to its reduced cost is the fact that sample processing does not require a separate nucleic acid (RNA) extraction step. This is significant because shortages of RNA extraction kits have been a recurrent issue since the beginning of the pandemic.

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CRISPR breakthroughs: New solutions for common diseases

Drug Discovery World

Nucleic acid-based diagnostics, which typically require PCR reagents and laboratory equipment, are crucial for identifying, treating, and preventing common infectious diseases. CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g.,

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Reflecting on PEGS Europe 2023 

Drug Discovery World

coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents. This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It kb Influenza A hemagglutinin gene was used as a model system.

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Casting aside CRISPR scissors and making a point with base editors

pharmaphorum

Dr Jennifer Harbottle, senior scientist in the R&D Base Editing team of PerkinElmer’s Horizon Discovery business, looks at progress made in the realms of biotechnology and next-generation diagnostics, vaccines and therapeutics, including the application of CRISPR-Cas9 gene editing in developing and refining cell therapies.

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Receptor Occupancy Assays by Flow Cytometry: Benefits for Clinical Trials

XTalks

Receptor occupancy assays have been developed and applied in both nonclinical and clinical studies to provide insight into PK/PD relationships so far,” said Andre Olsson, PhD, Senior Scientist, Flow Cytometry at the global contract research organization (CRO) Medpace. What is a Receptor Occupancy Assay? This process takes 14 to 16 weeks.

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Flow cytometry technologies and cancer associated fibroblasts

Drug Discovery World

Dr Amber Miller, Flow Cytometry Scientist, Fortis Life Sciences, says flow cytometry techniques can help our understanding of cancer associated fibroblasts but there is still work to be done. Elyada et al. This strategy identified a novel class of antigen presenting CAFs that were able to interact with CD4+ T cells3. 2016;165(4):780-791.