Scienmag

MARCH 9, 2022

A team led by scientists at the University of Birmingham has come a step closer to uncovering the purpose of a distinctive set of modifications found at the beginning of messenger RNA which have long remained a fundamental mystery in molecular biology. Messenger RNAs (mRNAs) are vital for protein production.

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The Pharma Data

JUNE 14, 2023

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. Interestingly, the researchers found that rather than encoding a protein, the gene encodes a small RNA that plays a vital role in bacterial respiration. aeruginosa infections.

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Drug Discovery World

SEPTEMBER 12, 2022

As the biopharmaceutical industry increases its focus on developing RNA therapeutics, the new RNA solution could help R&D organisations accelerate the delivery of drug candidates. The post New solution to boost RNA drug development appeared first on Drug Discovery World (DDW).

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pharmaphorum

OCTOBER 18, 2021

SMi Group’s 13th Annual Conference: RNA Therapeutics 2022. Bolstering the latest advances and opportunities in RNA-based medicine. Delve into the latest innovations in novel RNA delivery and target specificity. Engage in the growing advances and development of RNA tools for vaccines and anti-infectives. Senior Scientists.

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Scienmag

SEPTEMBER 29, 2021

JUPITER, FL – The American Chemical Society announced that its prestigious 2022 Nobel Laureate Signature Award for Graduate Education in Chemistry honors a student from the Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research and her faculty advisor, for their pioneering work developing RNA-targeting medications for genetic (..)

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Medical Xpress

APRIL 25, 2023

A team of international scientists led by the Heidelberg University, Medical Faculty Mannheim, and the Newcastle University (Great Britain) has succeeded in decoding a new mechanism of immune cell trafficking by examining vascular diseases.

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Scienmag

APRIL 19, 2022

A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate (..)

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Scienmag

MAY 3, 2021

Researchers who elucidated key functions of RNA, the workhorse molecule of cells, will be honored in October The 2021 Warren Alpert Foundation Prize has been awarded to scientists Lynne Maquat and Joan Steitz for seminal discoveries in the biology and function of RNA, the workhorse molecule of cells.

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Scienmag

MAY 3, 2022

LA JOLLA, CA—Scientists at Scripps Research have unveiled a new software tool for studying RNA (ribonucleic acid) molecules, which have a host of critical roles in organisms.

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Drug Discovery World

FEBRUARY 27, 2023

DDW’s Diana Spencer speaks to Raphael Townshend PhD, Founder and CEO of Atomic AI, about the company’s successes so far, plans for the future and the unique approach of combining RNA structural biology and AI models. DS: How is Atomic AI “unlocking the next generation of RNA drug discovery”? What is unique about your engine?

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Medical Xpress

APRIL 28, 2023

A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics. The study, led by Gustavo Garcia Jr. The study, led by Gustavo Garcia Jr.

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Drug Discovery World

AUGUST 16, 2023

Samir Ounzain , PhD, CEO & Co-Founder of HAYA Therapeutics, looks at how a better understanding of our DNA can lead to increased activity for RNA therapeutics. The whole world realised the power of RNA when the Covid-19 pandemic brought us the first mRNA-based vaccines.

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Medical Xpress

MARCH 1, 2023

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins that lead to the death of nerve cells in the most common subtypes of motor neuron disease (MND) and frontotemporal dementia (FTD).

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Scienmag

MARCH 12, 2021

Credit: The Wistar Institute PHILADELPHIA — (March 12, 2021) — Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome […].

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BioTech 365

JUNE 1, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists develop new method for ultra-high-throughput RNA sequencing in single cells.RNA sequencing is a powerful technology for studying cells and diseases.

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pharmaphorum

JANUARY 19, 2022

The collaboration aims to “close the gap between single-cell RNA sequencing wet-lab services and single-cell data analysis solutions,” which will allow scientists to study the finest details that can be hard to access. The post BioTuring enters collaboration to enable detailed single-cell RNA research appeared first on.

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BioTech 365

NOVEMBER 23, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants.After double fertilization, zygotic activation occurs that initiates a new life cycle, followed … Continue reading →

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Scienmag

OCTOBER 7, 2020

New technique breaks through a technology roadblock that limited RNA imaging for 50 years Credit: Kwaku Dayie/University of Maryland University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution.

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Scienmag

JUNE 2, 2021

Credit: Ron Bend/CSU A team of Colorado State University scientists, led by veterinary postdoctoral fellow Dr. Anna Fagre, has detected Zika virus RNA in free-ranging African bats. RNA, or ribonucleic acid, is a molecule that plays a central role in the function of genes.

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Scienmag

JUNE 9, 2022

NEW YORK, JUNE 9, 2022 – In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house. Credit: Memorial Sloan Kettering Cancer Center NEW YORK, JUNE […].

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Scienmag

APRIL 27, 2021

Credit: Nigel Michki Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

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Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

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Scienmag

NOVEMBER 6, 2020

JUPITER, FL–A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at […].

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BioTech 365

SEPTEMBER 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: RNA-targeting enzyme expands the CRISPR toolkit.Researchers at MIT’s McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists’ CRISPR toolkit, making … Continue (..)

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Pharmaceutical Technology

APRIL 20, 2023

Targovax has unveiled plans to rebrand as Circio , reflecting its strategic shift to focus on expediting the development of its innovative circular RNA (circRNA) platform. Initially reported in 2011, CircRNA is a naturally occurring class of RNA.

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Drug Discovery World

MARCH 21, 2024

A project focused on developing a small RNA-based platform technology for treating monogenic diseases, smartRNA, has joined the BioInnovation Institute’s (BII) Bio Studio programme. The technology has platform potential, as it leverages a universal small RNA pathway to target generic mRNA features.

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Scienmag

SEPTEMBER 30, 2020

Scientists are fighting back with multiple strategies, including vaccines, repurposed drugs developed for other diseases and brand-new therapies. Now, researchers reporting in ACS Central Science have identified small molecules that target a structure within the RNA genome […].

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Medical Xpress

DECEMBER 30, 2022

Messenger RNA vaccine technology, once an arcane area of research, became household terminology because of the COVID-19 pandemic, and now scientists are working on an mRNA flu vaccine strategy that, at least in this study, involves a first dose administered as a shot but a booster administered as an mRNA nasal spray.

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Medical Xpress

FEBRUARY 2, 2023

A new microfluidic device developed by scientists in Switzerland can detect the SARS-CoV-2 virus with high accuracy and speed, using a unique DNA/RNA duplex technology. The device could prove to be a game-changer in the fight against the ongoing COVID-19 pandemic.

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Scienmag

MAY 5, 2021

Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function. Credit: The Hong Kong University of Science and Technology The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics.

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Scienmag

JUNE 11, 2021

What The Study Did: Researchers compared the association between symptoms and SARS-CoV-2 RNA levels in children and adults. Authors: Erin Chung, M.D., of the University of Washington School of Medicine in Seattle, is the corresponding author. 2021.2025) Editor’s Note: The […].

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Drug Discovery World

APRIL 18, 2024

By building and iterating on RNA sequences through the CodonCracker software and the Nutcracker Manufacturing Unit, Nutcracker reported that its scientists engineered a group of molecules with attenuated PSMA and CD3 (cluster of differentiation 3) binding to mitigate on-target, off-tumour binding and target-independent T cell activation.

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Scienmag

MARCH 4, 2021

Findings explain how plants use RNA to defend against fungal invaders Credit: Nicole Ward Gauthier/University of Kentucky New research reveals an essential step in scientists’ quest to create targeted, more eco-friendly fungicides that protect food crops.

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Scienmag

MARCH 9, 2021

Scientists from the CNRS, INSERM, the AP-HP and the […]. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to fight this disease, which is due to the overexpression of a specific protein.

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Scienmag

APRIL 26, 2022

Using new analyses, scientists have just found the last two of the five informational units of DNA and RNA that had yet to be discovered in samples from meteorites. While it is unlikely that DNA could be formed in a meteorite, this discovery demonstrates that these genetic parts are available for delivery and could have […].

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Scienmag

JANUARY 13, 2022

14, 2022) – A molecule of RNA called CARMN has been found in abundance in the healthy smooth muscle cells that help give our blood vessels strength and flexibility, and distinctly decreased in vascular diseases like atherosclerosis, a major cause of heart attack and stroke, scientists report. AUGUSTA, Ga.

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Scienmag

MAY 7, 2021

The disorder, scientists found, is caused […].

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