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Modernizing cell culture processes for the next wave of genomic medicine

Pharmaceutical Technology

With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more. The field of genomic medicine has reached a true turning point.

Genome 244
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Monkeypox Test Kit in Development by Becton Dickinson in Partnership with CerTest Biotec

XTalks

As such, the smallpox vaccine can be used to protect against monkeypox — according to the WHO, the vaccine is 85 percent effective against monkeypox infection. While Roche’s monkeypox tests are not commercially available yet, they are available to scientists in most countries for research use.

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Yale-NBA Partnership Results in FDA Approval for COVID-19 SalivaDirect Test

XTalks

Instead of RNA extraction, the Yale test involves use of a reagent that when mixed with a saliva sample and heated for a short period of time, releases the viral genome for subsequent detection with PCR. Having a test that requires less reagents and resources, such as the RNA extraction kits, increases capabilities for increased testing.

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Biden Warns of 500,000 COVID Deaths by February

The Pharma Data

Next on the agenda: speeding up the nation’s vaccine rollout. To help do so, he’s directed the Federal Emergency Management Agency to begin constructing federally supported community vaccination centers, with the goal of having 100 centers in operation within the next month, The New York Times reported.

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Biden Unveils Details of National Pandemic Response Plan

The Pharma Data

He’ll also issue executive orders that aim to ramp up the production and distribution of COVID-19 tests and vaccines, make schools and travel safer, and help states fight the spread of coronavirus. The new plan also steers more money to states, which have complained they need more funding to test and vaccinate residents.

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Reflecting on PEGS Europe 2023 

Drug Discovery World

coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents. This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It kb Influenza A hemagglutinin gene was used as a model system.

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Casting aside CRISPR scissors and making a point with base editors

pharmaphorum

Dr Jennifer Harbottle, senior scientist in the R&D Base Editing team of PerkinElmer’s Horizon Discovery business, looks at progress made in the realms of biotechnology and next-generation diagnostics, vaccines and therapeutics, including the application of CRISPR-Cas9 gene editing in developing and refining cell therapies.