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‘Click’ chemistry used to tag proteins made by cancer cells 

Drug Discovery World

The new method involves adding chemical tags to sugar molecules which are added to cells. When the cells make these proteins, they remain marked with the chemical tag, meaning that researchers can identify them. . The method uses bioorthogonal or ‘click’ chemistry, which was awarded this year’s Nobel Prize in Chemistry.

Protein 52
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Women in Science Who Have Paved the Way Forward in Genetics

XTalks

Geneticist Martha Chase was a key partner of the foundational Hershey-Chase experiment that helped confirm DNA to be the carrier of genetic information; however, it was only Hershey of the pair that went on to win the Nobel Prize in Physiology or Medicine in 1969 for the discovery. Chase’s exclusion from the prize remains a mystery.

Genetics 119
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Lyfgenia and Casgevy Become First FDA-Approved Gene Therapies for Sickle Cell Disease

XTalks

The revolutionary CRISPR/Cas9 technology was discovered by Jennifer Doudna and CRISPR Therapeutics co-founder Emmanuelle Charpentier who both shared the 2020 Nobel Prize for it. Casgevy is also the first ever CRISPR/Cas9-based therapy approved in the US. Vertex-CRISPR’s Casgevy has a US list price of $2.2

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This week in drug discovery (24-28 October)

Drug Discovery World

Over the last seven days we’ve seen discoveries that could lead to new treatments for Covid-19, pancreatic cancer and Epstein-Barr virus, as well as the launch of the UK’s largest health research programme and the innovative application of a Nobel prize-winning chemistry technique. . This week’s top stories: .

Drugs 52
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Unveiling Potential: Exploring Alpha Emitter Radiopharmaceuticals

XTalks

Since Henri Becquerel’s discovery of natural radiation in 1896, Marie Curie’s Nobel Prize-winning work in discovering radium and polonium and William H. The aim of these compounds is to deliver radiation directly to the tumor cells, minimizing damage to surrounding healthy tissues.

DNA 66