Scienmag

MARCH 5, 2021

Scientists at Walter Reed Army Institute of Research, in a collaboration the Duke University, have confirmed that monoclonal antibodies can be an effective tool in the global fight against malaria.

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Medical Xpress

APRIL 25, 2023

In a new investigation, scientists from La Jolla Institute for Immunology (LJI) have shown how antibodies, collected from this clinical study volunteer, bind to the SARS-CoV-2 "Spike" protein to neutralize the virus. An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

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Medical Xpress

JANUARY 17, 2023

A new study led by scientists at La Jolla Institute for Immunology (LJI) shows how ideal antibodies against SARS-CoV-2 hit their marks.

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Scienmag

MAY 4, 2022

LA JOLLA, CA—Getting sick with a common cold doesn’t make you immune to COVID-19, but a COVID-19 infection might, at least temporarily, boost the number of antibodies you have against common cold-causing coronaviruses and the SARS-CoV-1 and MERS-CoV viruses, all of which are closely related.

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Bio Pharma Dive

JUNE 6, 2023

Agency scientists raised no major red flags in their review of the antibody medicine in documents posted ahead of a Thursday meeting of FDA advisers.

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Drug Discovery World

JANUARY 10, 2023

For over 50 years, Bethyl Laboratories (now a Fortis Life Sciences brand) has been dedicated to improving lives by supporting scientific discovery through qualified antibody products and custom services. All of our antibodies are highly validated using six pillars of validation, meaning that our antibodies do what we say they’ll do.

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Scienmag

MAY 31, 2022

LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have published the first analysis of how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2.

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Drug Discovery World

NOVEMBER 14, 2023

DDW’s Megan Thomas looks at how different diseases will benefit from the success of therapeutic antibodies. Cancer Monoclonal antibodies (mAbs) are a type of targeted drug therapy, and as such are often used to treat cancer. The global arthritis monoclonal antibodies market grew from $49.44 billion in 2022 to $53.81

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STAT News

AUGUST 23, 2022

As the world continues to learn how to live with Covid-19 in the long run, scientists are testing ways to quickly tell people how well-protected they are against the virus, and whether they need another booster.

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NY Times

OCTOBER 12, 2020

A network of scientists is chasing the pandemic’s holy grail: an antibody that protects against not just the virus, but also related pathogens that may threaten humans.

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Scienmag

APRIL 22, 2021

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

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pharmaphorum

JULY 27, 2021

Boehringer Ingelheim’s latecomer antibody therapy for COVID-19 has been side-lined, as the company focuses its attention on its thrombolytic drug alteplase, heading into a phase 3 programme later this year. The hope was that an inhaled antibody would reach higher levels in the lung, where it is most needed, than systemic antibodies.

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Scienmag

OCTOBER 26, 2021

A study conducted by a consortium of Brazilian researchers has demonstrated that a hyperimmune serum consisting of purified antibody fragments produced in horses may be an efficient approach to combat covid-19. The neutralizing activity of the sera developed by the scientists has been proved to be […].

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pharmaphorum

MARCH 16, 2021

million ($2 million) to develop its artificial intelligence-based platform for discovering therapeutic antibodies. The Cardiff, Wales startup is combining machine learning and phage display techniques to model antibody-antigen binding and says it can cut the time it takes to develop a drug candidate.

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Scienmag

OCTOBER 21, 2021

WHAT: A booster dose of the mRNA-1273 COVID-19 vaccine given to rhesus macaques about six months after their primary vaccine series significantly increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern, according to a new study from National Institutes of Health scientists and colleagues.

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Scienmag

SEPTEMBER 24, 2020

Findings point the way to developing a broad-spectrum flu drug Credit: Yanan Dai Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Together with an antibody that targets the other […].

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Scienmag

FEBRUARY 17, 2022

Scientists pinpoint mechanisms associated with severe COVID-19 blood clotting WHAT: After studying blood samples from 244 patients hospitalized for COVID-19, a group of researchers, including those who work at the National Institutes of Health, identified “rogue antibodies” that correlate with severe illness and may help explain mechanisms associated (..)

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Scienmag

FEBRUARY 25, 2021

Research from the California Institute of Technology shows exactly how antibodies stick to and block the Zika virus, which will inform vaccine development Credit: Image courtesy of Shannon Esswein.

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STAT News

NOVEMBER 21, 2022

Centuries later, scientists now know this to be a circadian rhythm, a 24-hour cycle that readjusts in response to environmental cues such as sunlight. Studies show that wounds heal faster during the day, and patients over 65 produce more antibodies if they get a flu shot in the morning. Read the rest…

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Scienmag

JUNE 29, 2021

Six antibody features help protect pregnant women against placental malaria infections, and could be used to identify women at risk of the disease and related complications Six antibody characteristics could help scientists identify which pregnant women are at risk of placental malaria infections, finds a study published today in eLife.

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Scienmag

SEPTEMBER 23, 2021

LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates.

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Scienmag

OCTOBER 22, 2020

The testing criteria had yet to be expanded to include individuals with Smith’s symptoms and so he did what many scientists with […]. Stephen Smith of Seattle Children’s Research Institute came down with muscle aches, gastrointestinal distress and a sudden loss of smell in late February, he suspected he had COVID-19.

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Scienmag

APRIL 22, 2021

SARS-CoV-2 can recruit a haem metabolite to evade antibody immunity Researchers have identified another potential target for neutralizing antibodies on the SARS-CoV-2 Spike protein that is masked by metabolites in the blood.

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pharmaphorum

MAY 3, 2022

A scientist working in Switzerland has become the fifth person to be convicted of attempting to steal trade secrets from pharmaceutical group GlaxoSmithKline in a case that stretched back several years. ” The post Fifth scientist convicted in GSK trade secrets case appeared first on.

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The Pharma Data

FEBRUARY 12, 2022

The discovery, published in Science Translational Medicine, could inform the design of broad-acting vaccines and antibody therapies capable of stopping future coronavirus pandemics. In the new work, they mapped at atomic scale the site, or “epitope,” to which the antibody binds on the SARS-Cov-2 spike protein.

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Scienmag

JUNE 1, 2021

Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected. Their results are published online today in the journal Cell.

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The Pharma Data

JUNE 30, 2021

For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.

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Scienmag

NOVEMBER 4, 2020

Credit: Rayne Zaayman-Gallant/EMBL The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the cell surface, the spike protein binds ACE2 using three finger-like protrusions, called the receptor binding domains (RBDs).

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Scienmag

AUGUST 17, 2020

— University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies. These antibodies may contribute to some of the negative side effects of long-term opioid use. MADISON, Wis.

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Drug Discovery World

APRIL 3, 2023

I quickly recognised the commercial value of aptamers as being able to address the gap in the market where antibodies fail to perform, and together we established the business to begin aptamer development. What advantages do they offer over antibodies?   To what do you attribute your success?

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Medical Xpress

APRIL 4, 2023

Critically ill COVID-19 patients often have antibodies in their blood that bind to the body's own structures, so-called autoantibodies. Scientists from the BIH at Charité and the Max Delbrück Center have now discovered that these autoantibodies frequently bind to not just one but multiple targets.

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Medical Xpress

JANUARY 27, 2023

COVID vaccines call our immune systems to action, generating antibodies which fight against any contact we have with the virus. Antibodies help to reduce the effects of an infection or even prevent it altogether. Scientists have estimated that vaccination has averted millions of COVID deaths worldwide.

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The Pharma Data

JANUARY 27, 2021

A new study has found that Eli Lilly and Regeneron may need to adjust their monoclonal antibody treatments to effectively fight fast-spreading COVID-19 variants, especially the South African mutation, which along with a UK variant has raised concerns among scientists that SARS-CoV-2 may mutate to resist vaccines and treatments.

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Scienmag

DECEMBER 16, 2020

Scientists at the Ragon Institute of MGH, MIT and Harvard find that neutralizing antibody potency predicts severe or fatal COVID-19. Of particular interest are neutralizing antibodies, which can block the virus from […]. Of particular interest are neutralizing antibodies, which can block the virus from […].

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Medical Xpress

FEBRUARY 17, 2023

The scientists developed a score that identifies patients at high risk of developing mutations owing to mAb treatment. A recent study conducted as part of the ORCHESTRA project has shed new light on the treatment of COVID-19 infections with mAbs.

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Medical Xpress

FEBRUARY 14, 2023

The immune system fights the coronavirus with antibodies and T cells. Scientists have a fairly good idea of how the virus avoids antibodies, including those promoted by vaccination, which is how variants of concern such as the omicron are known to appear. T cell evasion, on the other hand, has remained poorly understood.

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The Pharma Data

OCTOBER 27, 2021

A study conducted by a consortium of Brazilian researchers has demonstrated that a hyperimmune serum consisting of purified antibody fragments produced in horses may be an efficient approach to combat COVID-19. The neutralizing activity of the sera developed by the scientists has been proved to be high against the P.1 1 (Gamma) and P.2

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