Bacteria Protein RNA Scientist 
The Pharma Data
JUNE 14, 2023
Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. aeruginosa infections.
Drug Discovery World
MARCH 21, 2023
In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into the wild.
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XTalks
NOVEMBER 9, 2021
Perhaps popularized by the COVID-19 vaccines, RNA-based technologies now have the potential to become the next best pesticide to combat crop pests, like insects and fungal pathogens. Over the last year, researchers have been studying the effectiveness of RNA-based pesticides, and there are already a handful of sprays in the works.
Drug Discovery World
APRIL 30, 2024
Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. Its job is to carry coding information that is essential to the translation and processing of functional proteins.
Drug Discovery World
MAY 2, 2023
In the event of an attack from similar bacteriophages, the bacteria can recognise these segments and use this to discern and cleave the viral DNA, which disrupts the viral gene function. Bacterial RNA is replaced by a synthetic guide RNA (gRNA) that can recognise a specific target DNA sequence.
Drug Discovery World
AUGUST 10, 2022
The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells. Identifying the right CAR T cell target.
Drug Discovery World
JULY 18, 2023
Current research is focused on designing CRISPR-enhanced CAR T cells that are resistant to immunosuppressive cytokines such as transforming growth factor-β (TGF-β) 2 , programmed cell death protein (PD-1) 3 , or other negative T cell regulators 4 (CTLA-4, LAG-3, and TIM-3), thus improving anti-tumour functions.
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