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RNA holds the reins in bacteria: U-M researchers observe RNA controlling protein synthesis

Scienmag

Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria.

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. aeruginosa infections.

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#news #biotech Study describes new mechanism for terminating transcription of DNA into RNA in bacteria

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study describes new mechanism for terminating transcription of DNA into RNA in bacteria.A bacterial protein helps to stop transcription—the process of making RNA copies of DNA to … Continue reading →

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Australian sepsis study to power new antibiotic discoveries

Drug Discovery World

University of Queensland (UQ) researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics. The research team set out to find responses common to all four types of bacteria that cause sepsis and discover more about how bacteria survive in the body.

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Stop the genetic presses!

Scienmag

Study describes new mechanism for terminating transcription of DNA into RNA in bacteria Credit: Babitzke Laboratory and Dani Zemba, Penn State The protein, known as NusG, pauses the transcription machinery at specific DNA sequences to facilitate what is called “intrinsic termination” and prevent unwanted transcription that could disrupt (..)

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Scientists engineer safe, virus-resistant E coli for research

Drug Discovery World

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into the wild.

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Gene Therapy and Pharmacokinetics

Camargo

Viruses and bacteria can be first modified to prevent them from causing infectious diseases and then implemented into human tissues as therapeutic gene vectors. For example, it is beneficial to administer RNA treatments for some lung diseases directly to the disease site through inhalation. Route of Administration Considerations.