Roots Analysis
NOVEMBER 30, 2021
Bioassay – A Prerequisite for the Cell and Gene Therapy Development. Over the past few years, investigational new drug (IND) filings for cell and gene therapy product have significantly increased. Bioassays are biochemical procedures that are used to evaluate the potency, purity and efficacy of a drug substance.
pharmaphorum
AUGUST 5, 2021
Understanding the mechanism of PPIs and developing methods to target aberrant ones has been a key strategy in drug development. In comparison with the classic, small molecule drug discovery approach, the modulation of PPIs is more challenging. Current challenges and conventional approaches in targeting PPIs. Charlotte Di Salvo.
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Drug Discovery World
MAY 4, 2023
Professor Sonika Bhatnagar explores how artificial intelligence is enabling drug discovery at rates never seen before. Here started the story of drug discovery. The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target.
Drug Discovery World
NOVEMBER 30, 2023
Next-generation immunotherapies In the session focused on cell-based immunotherapies, Steven Quistad, Senior Applications Scientist, DNA Script, presented on how to rapidly assemble genes in a laboratory using automated enzymatic oligo synthesis. To demonstrate the utility of the company’s SYNTAX system in gene assembly, the 1.7
Drug Discovery World
NOVEMBER 9, 2023
The first three include: Sungjin Park, PhD, CEO, Onegene Biotechnology, on: ‘UniStac: Enzyme-mediated conjugation technology for accelerated development of tetraspecific NASH drug’. Ioanna Stamati, PhD, Team Leader, Bioconjugation, Antikor Biopharma, on: ‘Antibody fragment drug-conjugates (FDCs): Analysing novel formats with high DAR’.
Drug Discovery World
MAY 10, 2023
Dr Megan MacBride and Dr Caroline Horizny Mitchell , Taconic, examine recent changes to animal testing in drug design. Drug discovery and development is an arduous process that can cost upwards of $2.6 In August 2022, the ICH issued an addendum to its S1B guidelines that allows certain drugs to forego two-year rat studies 1.
The Pharma Data
MAY 13, 2021
Nat Rev Drug Discov. The obesity epidemic and food addiction: clinical similarities to drug dependence. J Psychoactive Drugs. Curr Drug Abuse Rev. Addicted to Palatable Foods: Comparing the Neurobiology of Bulimia Nervosa to that of Drug Addiction. Aspartame bioassay findings portend human cancer hazards.
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