Roots Analysis
NOVEMBER 30, 2021
Bioassay – A Prerequisite for the Cell and Gene Therapy Development. Therefore, increase in development of cell and gene therapy domain has led to the rise in demand of bioassay services for cell and gene therapy. Bioassays are biochemical procedures that are used to evaluate the potency, purity and efficacy of a drug substance.
Drug Discovery World
FEBRUARY 23, 2023
Proteins are the basic building blocks and engines of biology. For decades, drug discovery and development have been constrained by limits in our knowledge of the relationship between protein sequence, structure and function, and the methods available to explore novel drug targets.
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Drug Discovery World
JANUARY 19, 2023
This paid-for advertorial by Sphere Fluidics appeared in the SLAS 2023 Supplement, Volume 24 – Issue 1, Winter 2022/2023 Cell engineering is being held back by lengthy and complicated multi-step workflows. Sphere Fluidics’ Cyto-Mine ® system offers a streamlined, automated solution to this challenge using picodroplet microfluidic technology.
Drug Discovery World
NOVEMBER 9, 2023
Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Croasdale-Wood will then participate in a keynote chat, interviewed by Miho.
Drug Discovery World
MAY 4, 2023
The drug target for Penicillin is a protein that helps bacteria to synthesise its cell wall. One of the first and most basic requirements for a protein to be characterised as a drug target is to show that inhibiting its function prevents the disease. Salvarsan was soon overtaken by the Penicillin antibiotics.
Drug Discovery World
NOVEMBER 30, 2023
This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents. GSK has developed high-throughput mammalian and E.
The Pharma Data
MAY 13, 2021
Aspartame bioassay findings portend human cancer hazards. Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level. Journal of Food Engineering. Huang D, Dhawan T, Young S, et al. Fructose impairs glucose-induced hepatic triglyceride synthesis.
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