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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

It is a popular method in systems biology, requiring fewer compounds to be screened in bioassays, reducing time and cost. A PPI network was constructed from nine colon stem cell markers in order to identify potential genetic targets in patients.

Protein 123
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Accelerating NDA filing through faster carcinogenicity assessment

Drug Discovery World

Carcinogenicity testing For decades, the two-year rodent bioassay has been the regulatory standard used to determine the carcinogenic potential of new drugs. This process historically involved lifetime carcinogenicity bioassays in two species. Figure 1: Comparing Carcinogenicity Testing Timelines in Transgenic vs. Standard Mice.

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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Advances in analytical techniques and approaches This session is made up of four presentations which include: Christian Graf, PhD, Fellow, Scientific Office, Novartis TRD Biologics, on: ‘MS-based cell bioassays: A novel tool for biotherapeutics characterisation’.

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Let's Quit Sugar With Audiobook – Let's Quit Sugar

The Pharma Data

Aspartame bioassay findings portend human cancer hazards. Neural and Genetic Correlates of the Social Sharing of Happiness. Huang D, Dhawan T, Young S, et al. Fructose impairs glucose-induced hepatic triglyceride synthesis. Lipids Health Dis. 2011;10:20 DOI: 10.1186/1476-511X-10-20 . Huff J, LaDou J. Int J Occup Environ Health.

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