Drug Discovery World

SEPTEMBER 20, 2022

The study also identified similarities with genes that are believed to be associated with multiple sclerosis (MS) and long Covid. Each circle represents a disease-associated SNP genotype, edges represent their co-association in patients in disease signature(s), and colours represent distinct patient sub-populations.

Genetics 52

Genetics Biobanking Genotype Gene 52

pharmaphorum

JANUARY 24, 2023

Pharma has used this to begin creating targeted treatments, such as gene therapies , which are able to hone in on gene mutations that cause health issues and eradicate or replace the faulty gene. Scientists are able to study the aggregated, de-identified genetics of these individuals.

Genetics 95

Genetics Drugs Genome Project Biobanking 95

Drug Discovery World

OCTOBER 30, 2023

RA: You’ve recently announced a collaboration with the University of Oxford to access genotype data on women with endometriosis. We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients.

Genome 72

Genome Genomics Genotype Clinical Trials 72

XTalks

APRIL 15, 2021

From a total of 30 single-nucleotide polymorphisms (SNPs) in genes previously identified as being associated with blood pressure, many had a relatively neutral effect on the risk of coronary artery disease. Figure 2: Using drug-target MR to validate sympathetic nervous system genes involved in heart failure.

Development 98

Development Drugs Genome Genomics 98