Drug Discovery World

OCTOBER 26, 2022

A study by the Qatar Genome Research Consortium, led by Dr Lotfi Chouchane from Weill Cornell Medicine-Qatar, has reported the first landscape of cancer germline mutations – hereditary mutations – in the Qatari population. . These variants increase the risk of developing breast cancer in women and prostate cancer in men. .

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Drug Discovery World

DECEMBER 15, 2022

This is the latest episode of the free narrated DDW podcast , “Is genomic data the new frontier in drug discovery?” They are called “ Genomics boosts understanding of Covid-19 severity and susceptibility ” and “ Rare variant contribution to human disease ”. Listen here: The post Is genomic data the new frontier in drug discovery?

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pharmaphorum

JANUARY 18, 2023

However, the Resilience Project’s scientists had used genomic data originally collected for other studies and, due to limitations in the original studies’ informed consent policies and a lack of infrastructure to recontact participants, none of the 13 individuals could be contacted with follow-up questions or requests.

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Medical Xpress

MARCH 9, 2023

Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are also the leading cause of blindness certification in working-age adults.

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Pharmaceutical Technology

JUNE 20, 2023

The new AIID building will include a human infection challenge unit, high-containment facilities, a robotic biobanking facility, interview rooms, dry laboratories and spaces for community engagement and co-design work. It will be connected across multiple levels to the University of Melbourne’s Doherty Institute.

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Drug Discovery World

MARCH 7, 2023

Within this, Qatar is emerging as a country which is actively seeking to bolster its drug discovery and development sectors, through high levels of spending and investment into local research programmes. Qatar is a small country but faces many of the same healthcare problems that Western countries currently face.

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Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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The Pharma Data

MARCH 1, 2022

to build a scalable data, analytics, and infrastructure platform This collaboration aims at capturing translational disease insights from large external healthcare biobanks and maximizing value of data for drug discovery and precision medicine. Boehringer Ingelheim partners with Lifebit Biotech, Ltd.

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XTalks

SEPTEMBER 16, 2022

Researchers at the Francis Crick Institute and University College London in the UK have found how air pollution can trigger the activation of cells with existing genetic mutations to form cancer. The researchers propose that particulate matter 2.5 The new research shows that air pollutants can be that ‘second hit.’

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Drug Discovery World

APRIL 4, 2024

The university will also support the European Union’s 1+ Million Genomes initiative, which seeks to boost innovation in healthcare across Europe. Driving new understanding 10,000 whole human genomes will be sequenced and analysed by the Institute of Genomics at the University of Tartu.

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Drug Discovery World

SEPTEMBER 20, 2022

To develop safe and effective gene therapies, researchers need confidence that genomic data is both complete and accurate. This considerable magnitude of difference in read length affords researchers a more complete and accurate view of genomic variation.

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pharmaphorum

MARCH 19, 2021

on Big data: astronomical or genomical? , by 2025 more than 500 million human genomes will be sequenced, creating more data than YouTube and Twitter combined. According to an article by Stephens, Zachary D.,

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pharmaphorum

JANUARY 24, 2023

One of the reasons is because researchers now have far more genetic data to work with than was ever previously possible. The cost of testing per human genome in 2006 was approximately $14 million , and in less than two decades, an average consumer-purchased genetic test costs $100.

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pharmaphorum

DECEMBER 2, 2021

GlaxoSmithKline has formed a five-year partnership with Oxford University to set up a new institute that will apply machine learning and functional genomics to the discovery of new medicines. ” The post GSK pumps £30m into a new Oxford University partnership appeared first on.

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XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Generation of strong research dataset cohorts must begin with high-quality clinical samples. Biobanks are used for the coordination of high-yield patient sample collection.

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The Pharma Data

APRIL 11, 2023

Bayer is progressing novel research around its prostate cancer treatment darolutamide. Both small molecule inhibitors in Immuno-Oncology are being jointly developed in a strategic research alliance with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

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Drug Discovery World

FEBRUARY 27, 2024

Reece A: What are some of the human limitations to current drug discovery research for immunotherapies? While we have made a lot of progress in targeted therapeutics by identifying molecular tumour drivers that define patient subsets, genomics has not quite produced the same level of understanding for tumour-immune biology.

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pharmaphorum

JULY 5, 2022

George Freeman, minister for science, research and innovation at the Department for Business, Energy and Industrial Strategy, opened proceedings by reminding us of some of the UK’s recent achievements and aspirations for the future. Faster access for patients for interventions. Data on all aspects, including stratification of patient types.

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The Pharma Data

JULY 15, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. (Nasdaq: BIIB) and Pfizer (NYSE: PFE). These genetic data have been paired with detailed health information to create this browsable resource.

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The Pharma Data

JULY 8, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. (Nasdaq: BIIB) and Pfizer (NYSE: PFE). These genetic data have been paired with detailed health information to create this browsable resource.

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XTalks

APRIL 15, 2021

New advances in heart failure genomics are helping to address this challenge. Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. Watch this on-demand webinar to hear from these experts.

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Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. Genomic medicine has therefore had limited impact on improving diagnosis or treatment in endometriosis and other chronic diseases.

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The Pharma Data

JANUARY 20, 2021

The UK biobank released a further dataset on COVID-19 positive patients consisting of ~4,000 confirmed COVID-19 infected patients in November 2020. The laboratory reagents are being independently cross validated at the Australian Genome Research facility (AGRF).

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