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NSF backs bioinformatics approach to understanding plant RNA modifications

Scienmag

Led by Boyce Thompson Institute’s Andrew Nelson, four partners will identify RNA modifications and develop resources that may lead to hardier crops Credit: Photo credit: Anna Nelson Dittrich ITHACA, NY, August 4, 2020 — RNA perform a variety of functions in cells, helping with everything from regulating genes to building proteins.

RNA 74
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Country focus: Hungary carves out a niche in digital pharma

pharmaphorum

“For example, you can simulate what would happen if you inhibited thousands of different proteins in thousands of different cell models.”. They go into bioinformatics”. They go into bioinformatics.”. I expect that grant funders and regulators will also ultimately insist that these tools be deployed to increase success rates. “In

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Big data – charting a new path to drug discovery and development

Drug Discovery World

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

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STAT+: Foundation charges cancer patients $83,000 for unproven but promising experimental drug

STAT News

“There isn’t a member of the board of JLF who wouldn’t rather be able to do this without charging people,” said Andrew Jacobs, who sits on the boards of the foundation and NorRD Bio, a small Cambridge bioinformatics firm that helps make the vaccines. “It really was a choice of this or nothing.”

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

He is being recognised for illuminating research contributions to defining the links between chromosomal abnormalities and cancer, including his discovery of TMPRSS2-ETS gene fusions in prostate cancer, and for pioneering the use of pathological and bioinformatic methodologies to diagnose and track prostate cancer onset and progression.

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Could elephant genes hold the key to avoiding cancers?

Drug Discovery World

Scientists from seven research institutions including the University of Oxford and the University of Edinburgh have used pioneering bioinformatic modelling to investigate the molecular interactions of the p53 protein known to give protection against cancers.

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