Clinical Trials and Trials - Clinical Research Informer

How to connect patients with rare diseases to clinical trials

Pharmaceutical Technology

SEPTEMBER 18, 2023

Experts say a wider diverse pool of patients needs to be given a chance to participate in clinical trials to get rare disease drugs faster to market.

Clinical Trials

September 5, 2023: NIH Pragmatic Trials Collaboratory Announces Grand Rounds Series on Design and Analysis of Pragmatic Clinical Trials

Rethinking Clinical Trials

SEPTEMBER 5, 2023

The NIH Pragmatic Trials Collaboratory is launching a special Grand Rounds series to share advances in the design and analysis of pragmatic clinical trials. Recordings will be archived on the Rethinking Clinical Trials website. The series will include 3 additional moderated webinar discussions.

Clinical Trials

Decentralized clinical trials (DCTs): protect your data to reduce risk

Bio Pharma Dive

JUNE 12, 2023

Decentralized clinical trials (DCTs) bring many benefits to the clinical research process, and more importantly, the patients. However, it is important to remember the risks if there is no data security process in place.

Clinical Trials

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management.

Clinical Trials

How the right technology and tools can accelerate progress in rare disease clinical trials

Bio Pharma Dive

AUGUST 7, 2023

Fortunately, technology has created opportunities to innovate in clinical trials for rare diseases. The need for more research into rare diseases is clear, but researchers face significant challenges.

Clinical Trials

New Weight Loss Drug May Launch in US After Promising Clinical Trial

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 3, 2023

Pharmaceutical giant Eli Lilly said Thursday it will seek approval to add its diabetes drug to the buzzy US weight loss market after achieving promising results in a new clinical trial. Tirzepatide, currently approved to treat type 2 diabetes under the name Mounjaro, is taken once a week as an injection. Eli Lilly said its […]

Clinical Trials

Data Sharing and Pragmatic Clinical Trials: Law & Ethics Amidst a Changing Policy Landscape

Rethinking Clinical Trials

AUGUST 9, 2023

Data Sharing and Pragmatic Clinical Trials: Law & Ethics Amidst a Changing Policy Landscape Description Kayte Spector-Bagdady and Stephanie Morain discuss the impact of a changing policy landscape on data sharing and pragmatic clinical trials.

Clinical Trials

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Responding (or Not) to Signals of Potential Clinical Significance in Pragmatic Clinical Trials

Rethinking Clinical Trials

AUGUST 9, 2023

Responding (or Not) to Signals of Potential Clinical Significance in Pragmatic Clinical Trials Description Joseph Ali, Tanya Matthews, and Leslie J. Crofford discuss responding (or not) to signals of potential clinical significance in pragmatic clinical trials.

Clinical Trials

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies.

Clinical Trials

August 17, 2023: American Journal of Bioethics Publishes Special Issue on Pragmatic Clinical Trials

Rethinking Clinical Trials

AUGUST 17, 2023

When research and clinical care are deliberately integrated in an embedded pragmatic clinical trial, the nature and extent of investigators’ obligations to patient-subjects are blurred, as is the clinician’s duty to participate is such research. Wilfond, Sinem Toraman Turk, Stephanie A. Kraft, Elliott M.

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Virtual clinical trials: How digital tech has improved clinical trial accrual rates

Pharmaceutical Technology

MAY 18, 2023

For clinical trial participants, dropping out of trials is often due to the distances from their homes to the trial sites, combined with unexpected costs and number of visits needed. Add in complex trial protocols, and many participants have reported feeling a lack of patient engagement and support [i].

Clinical Trials

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Including Diverse Participants in Pragmatic Clinical Trials

Rethinking Clinical Trials

AUGUST 8, 2023

Karen Kehl of the National Institute of Nursing Research discuss the important of including diverse participants in pragmatic trials, including highlights from a panel discussion at the NIH Pragmatic Trials Collaboratory 2022 Steering Committee Meeting.

Clinical Trials

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Untangling the Complexities of Cell and Gene Therapy Clinical Trials: A Supply Chain Perspective

Pharmaceutical Technology

MAY 24, 2023

By Luisa Sterkel & Joana Loureiro , Tenthpin Consultants The promise and potential of cell and gene therapies (CGT) has emerged in the recent past and currently over 1.500 CGT are registered for clinical trials holding great hope for the treatment of challenging and uncurable diseases.

Clinical Trials

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management.

Clinical Trials

Hope for the UK clinical trial landscape but it requires a lot of work

Pharmaceutical Technology

SEPTEMBER 8, 2023

The Arena International Outsourcing in Clinical Trials UK and Ireland discussed how the UK’s clinical trial landscape has taken a hit and what improvements are needed to make it a more viable country for research.

Clinical Trials

Implementation and Intervention Complexity in Pragmatic Clinical Trials

Rethinking Clinical Trials

AUGUST 8, 2023

Implementation and Intervention Complexity in Pragmatic Clinical Trials Description Dr. Steven George of Duke University discusses implementation and intervention complexity in pragmatic trials, including highlights from a panel discussion at the NIH Pragmatic Trials Collaboratory's 2022 Steering Committee Meeting.

Clinical Trials

Unveiling the Future: Key Trends in Clinical Trial Technology

Pharma Mirror

JUNE 15, 2023

In recent years, the field of clinical trials has witnessed a significant transformation due to advancements in technology. The integration of technology into clinical trials has revolutionized the way researchers conduct studies, collect data, and analyze results.

Clinical Trials

June 28, 2023: In This Week’s PCT Grand Rounds, What’s Left for Decentralized Clinical Trials?

Rethinking Clinical Trials

JUNE 28, 2023

In this Friday’s PCT Grand Rounds, Adrian Hernandez, Pamela Tenaerts, and Craig Lipset will present “Decentralized Trials – From Guidance to Reality & What’s Left.” Tenaerts is the chief scientific officer of Medable, a cloud computing platform for decentralized clinical trials. Join the online meeting.

Clinical Trials

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Running Decentralized Trials at Scale: Planning for Success

There’s been a rapid shift towards decentralization in clinical trials & it’s clear why. The potential for reaching a larger pool of recruits is possible when sponsors can bring more trial activities to the patient. Most trials won’t be fully virtual, but all trials will be more virtual.

Trials

ICON partners with US Government for clinical trials of Covid-19 vaccines

Pharmaceutical Technology

SEPTEMBER 14, 2023

ICON will conduct Phase IIb clinical trials for the US BARDA-selected Covid-19 vaccine candidates as part of ‘Project NextGen’.

Clinical Trials

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Building a Study Team for a Pragmatic Clinical Trial

Rethinking Clinical Trials

JULY 31, 2023

Building a Study Team for a Pragmatic Clinical Trial Description NIH Collaboratory investigator Dr. Lesley Curtis shares tips for building effective study teams for pragmatic clinical trials.

Clinical Trials

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Clinical trials face increasing challenges

Bio Pharma Dive

NOVEMBER 8, 2021

The COVID-19 pandemic emerged at a time when the clinical trial landscape had reached a peak in complexity. Global trials are now commonplace as drug makers seek to establish efficacy in diverse populations.

Clinical Trials

More diverse staff may yield diverse patient groups in clinical trials

Pharmaceutical Technology

SEPTEMBER 5, 2023

Lack of diversity in clinical trials is a result of lack of trust from those in the community but there are methods to overcome this.

Clinical Trials

How using AI in clinical trials accelerates drug development

Pharmaceutical Technology

JUNE 15, 2023

But before pharmaceutical companies can go to market with a breakthrough drug, they need to ensure safety and efficacy through clinical trials. Pharma R&D teams are solving this problem by leveraging the power of artificial intelligence (AI) in clinical trials to save time and money.

Clinical Trials

Clinical Trials For All Campaign: Converging Trials and Healthcare

XTalks

AUGUST 22, 2023

Recruiting participants is perhaps the most challenging aspect of any clinical trial, regardless of the therapeutic area. Yet this one piece is also the most vital, with a trial’s ability to enroll and retain participants being a key predictor of a study’s future success. What is Clinical Trials For All?

Clinical Trials

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FDA drug dosage optimisation guidelines signal clinical trial reform

Pharmaceutical Technology

FEBRUARY 17, 2023

The agency proposes that pharma move away from the common maximum tolerated dose (MTD) to trial designs that prioritise drug dosage optimisation at different stages. In clinical trials, dose-ranging is testing different drug doses against each other to establish which works best.

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We must improve diversity in clinical trials. These 5 steps will help.

Bio Pharma Dive

DECEMBER 5, 2022

The pandemic shined a light on the importance of diversity in clinical trials. Syneos Health can help your team devise a diversity strategy.

Clinical Trials

Kroger Health works to expand access to clinical trials

Bio Pharma Dive

MARCH 6, 2023

Kroger Health seeks to increase awareness among more eligible clinical trial participants.

Clinical Trials

Oregon Project Extends Benefits of Clinical Trials to More Hispanics/Latinos

ACRP blog

SEPTEMBER 13, 2023

With observations of National Hispanic Heritage Month kicking off on September 15, this year’s events will have special resonance for a team of Oregon Health & Science University (OHSU) researchers who are working to bring the benefits of clinical trials to more persons in underserved communities.

Clinical Trials

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Patient-centered clinical trials improve recruitment and retention

Bio Pharma Dive

APRIL 17, 2023

Patient enrollment in clinical trials is time-intensive & costly. Let’s face facts. We must do better.

Clinical Trials

5 reasons why it's so hard to find clinical trial volunteers

Antidote

SEPTEMBER 13, 2023

Globally, there are thousands of research studies and clinical trials conducted each year, all with the shared goal of bringing new treatment options and medical devices to the market. However, approximately 80% of clinical trials are delayed or closed because of problems with recruitment.

Clinical Trials

Ophthalmology disorders and current developments of novel treatments under clinical trials

ProRelix Research

SEPTEMBER 17, 2023

Since […] The post Ophthalmology disorders and current developments of novel treatments under clinical trials appeared first on ProRelix Research.

Clinical Trials

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UK scientists prepare for Nipah virus clinical trial

Drug Discovery World

SEPTEMBER 19, 2023

The University of Oxford has revealed that researchers are currently in the advanced stages of preparing for a clinical trial of a Nipah vaccine using the ChAdOx1 vector. The post UK scientists prepare for Nipah virus clinical trial appeared first on Drug Discovery World (DDW).

Clinical Trials

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Do clinical trials pay for travel?

Antidote

JULY 14, 2023

For medical research to advance, the participation of individuals in a clinical trial is essential. However, accessing trial sites can present an undue burden.

Clinical Trials

Older UK people back auto-enrolment in clinical trials

pharmaphorum

SEPTEMBER 19, 2023

Older UK people back auto-enrolment in clinical trials Phil.Taylor Tue, 19/09/2023 - 08:55 Bookmark this

Clinical Trials

Decentralized Clinical Trial Management: The Future of Clinical Trials

Cloudbyz

MARCH 19, 2023

Decentralized Clinical Trial Management is a new approach to conducting clinical trials that leverages decentralized technologies such as blockchain, smart contracts, and distributed computing to streamline the clinical trial process. Additionally, all data is encrypted, making it secure from cyber threats.

Clinical Trials

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Successful Clinical Trial With ProRelix Research: Phase 1, 2, 3 & 4 Clinical Trial Services at …

ProRelix Research

MAY 31, 2023

Introduction: Clinical trials are a crucial component of the pharmaceutical and medical research industry, aimed at evaluating the safety and effectiveness of new drugs, treatments, or medical devices before they […] The post Successful Clinical Trial With ProRelix Research: Phase 1, 2, 3 & 4 Clinical Trial Services at … appeared (..)

Clinical Trials

Why Is CVS Health Clinical Trial Services Closing?

XTalks

MAY 24, 2023

Leading health solutions company CVS Health recently disclosed that its clinical trial business will shut down just two years after its initiation in May 2021. The company will gradually wind down its CVS Health Clinical Trial Services unit with full exit by December 31, 2024.

Clinical Trials

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Importer of Record for Clinical Trials

Imperical Blog

SEPTEMBER 7, 2023

Avoiding “Customs Chaos” in Clinical Trials Means Working Closely with Your Importer of Record Many global clinical trial shipments get muddled regarding the critical role and responsibilities of the importer of record (IOR) for clinical trials.

Clinical Trials

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Importer of Record for Clinical Trials

Imperical Blog

SEPTEMBER 7, 2023

Avoiding “Customs Chaos” in Clinical Trials Means Working Closely with Your Importer of Record Many global clinical trial shipments get muddled regarding the critical role and responsibilities of the importer of record (IOR) for clinical trials.

Clinical Trials

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Clinical Trial Manager Jobs: What You Should Know

XTalks

MAY 9, 2023

Clinical trial manager jobs are vital for the development and execution of clinical trials, which are essential for developing new treatments for diseases. In this article, we discuss the job duties, education and experience requirements, outlook and salary expectations for clinical trial managers.

Clinical Trials

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Decentralized Clinical Trials in a Post-Pandemic Era

ACRP blog

SEPTEMBER 11, 2023

Overview Decentralized clinical trials (DCTs) represent the shift towards implementing virtual research studies using digital health tools to gather data and monitor patient activity. During the COVID-19 pandemic, the clinical industry experienced significant disruption to traditional practices. This is a sponsored message.

Clinical Trials