Remove Development Remove Drugs Remove In-Vivo Remove Reagent
article thumbnail

Breakthrough ‘nanobody’ technology boosts thrombosis research

Drug Discovery World

The research team, led by Professor Steve Watson and Dr Eleyna Martin, developed antibody fragments called nanobodies and crosslinked these to make ligands to four platelet receptors (GPVI, CLEC-2, FcɣRIIA and PEAR1). Reagents based on nanobodies will increase our understanding of platelet activation in the laboratory.

article thumbnail

Reflecting on ELRIG’s Drug Discovery 2022 

Drug Discovery World

The DDW team spent 4-5 October, 2022 at ELRIG’s annual meeting, Drug Discovery 2022, which remains Europe’s largest meeting for life sciences industry professionals and took place at ExCel, London, UK. Drug Discovery 2022: The numbers . Drug Discovery 2022: The numbers . Of those delegates, 75% work in drug discovery.

Drugs 52
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Fortis Life Sciences leads the way in custom antibody discovery

Drug Discovery World

In the ever-evolving landscape of therapeutic development, the role of antibodies has become increasingly apparent. Antibodies are used as therapeutics, components of therapeutics such as antibody-drug conjugates (ADC) and CAR-T cells, and as companion diagnostic tools. This article is sponsored by Fortis Life Sciences.

article thumbnail

Reflecting on PEGS Europe 2023 

Drug Discovery World

Lightcast is developing a novel, programmable microfluidic platform that allows precise and highly flexible control of individual microdroplets using software-generated light patterns. GSK has developed high-throughput mammalian and E.

article thumbnail

Delivering on the promise of gene editing

Drug Discovery World

Possible solutions: A new generation of gene editing tools is being developed to avoid double stranded breaks altogether and to be potentially less destructive than traditional nuclease systems. In vivo approaches involve delivering the gene editing components directly into the patient. In one example, Choi et al.

article thumbnail

The evolution of assays for immuno-oncology research

Drug Discovery World

Evolution of such defence mechanisms can lead to multi-drug resistance, further disease progression, and cancer metastasis. Further discovery of PD-1 and CTLA4 as negative immune regulators led to the development of a new class of cancer therapeutics, namely the immune checkpoint inhibitors 5,6.

article thumbnail

Global Roundup: EU Approves ViiV’s HIV-1 Drug and More

The Pharma Data

In July, ViiV Healthcare, which is based in London, resubmitted the New Drug Application (NDA) for once-monthly dosing of cabotegravir and rilpivirine to the U.S. In July, ViiV Healthcare, which is based in London, resubmitted the New Drug Application (NDA) for once-monthly dosing of cabotegravir and rilpivirine to the U.S.

Drugs 52