Medical Xpress

NOVEMBER 7, 2022

Researchers have discovered the vital role of a hormone, which develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life.

Hormones 98

Hormones Development Research 98

Pharmaceutical Technology

JULY 13, 2022

Merck (MSD outside North America) and Orion have entered an international agreement to develop and market the latter’s investigational candidate ODM-208 to treat metastatic castration-resistant prostate cancer (mCRPC). Orion discovered and developed ODM-208 to treat hormone-dependent cancers, such as prostate cancer.

Development 264

Development Hormones Production Marketing 264

XTalks

JULY 6, 2023

Pfizer has been going strong on the approval front, having secured its fifth US Food and Drug Administration (FDA) approval in the past five weeks, with the most recent being for the company’s once-weekly human growth hormone analog Ngenla (somatrogon-ghla). Pfizer paid OPKO $295 million upfront at the beginning of the partnership.

Hormones 98

Hormones FDA Approval Clinical Trials Clinical Trials 98

Medical Xpress

NOVEMBER 15, 2022

Reproductive health experts consider hormonal contraceptives good choices for adolescents because they're safe and highly effective at preventing pregnancy, but one aspect of their effect on the teenage body remains a mystery—whether and how they modify the developing brain.

Hormones 96

Hormones Development 96

Drug Discovery World

NOVEMBER 16, 2022

The end goal is to expand the range of accessible non-hormonal contraceptive choices for women in developing countries. . To date, research on discovering non-hormonal contraceptive agents has been hindered by a dearth of validated and enabled drug targets. . The post CAD$2.4M

Hormones 52

Hormones Drugs Development Research 52

STAT News

AUGUST 8, 2022

Aldosterone, a hormone produced by the triangular adrenal glands, might be the key target.    In the observational study, researchers analyzed health data from 3,680 people with chronic kidney disease for nearly 10 years. Read the rest…

Hormones 98

Hormones Research Development Drugs 98

Medical Xpress

MARCH 1, 2023

Controversies surrounding hormone therapy (HT) and its benefits and risks have dominated the women's health field for more than 2 decades. A large new study demonstrates that, despite some commonly held misperceptions, HT doesn't increase a woman's risk of developing lung cancer, and it could actually help reduce the risk.

Hormones 71

Hormones Development 71

Medical Xpress

APRIL 3, 2023

Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD. A new study, led by Mass General Brigham researchers, sheds light on the relationship between the risk of Alzheimer's disease and age of menopause and use of hormone therapy (HT).

Hormones 81

Hormones Development Research 81

BioSpace

JANUARY 3, 2021

Pfizer and OPKO Health are one step closer to receiving approval for their jointly developed pediatric growth hormone deficiency drug, somatrogon, after the U.S. FDA recently accepted the companies’ regulatory submission for the therapy.

Hormones 106

Hormones Drugs Development 106

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 17, 2023

New research by our team has identified sensitivity to a hormone made in abundance by the developing pregnancy, GDF15, […] Sickness in pregnancy, or hyperemesis gravidarum, is common and is thought to affect seven out of ten women at some time in their pregnancy.

Hormones 214

Hormones Research Development Clinical Trials 214

XTalks

JANUARY 23, 2024

Among these, rare pediatric diseases present unique challenges and opportunities for rare disease drug development. Pediatric growth hormone deficiency (PGHD) is one such condition, affecting a child’s growth and development.

Development 72

Development Hormones Drugs Trials 72

Scienmag

JUNE 22, 2021

Women who currently use hormonal contraceptives face more than a 2-fold higher risk of developing glaucoma, according to an analysis of electronic medical records for women aged 15-45 years from 2008 to 2018. The British Journal of Clinical Pharmacology analysis included 2,366 women who developed glaucoma and 9,464 controls.

Hormones 52

Hormones Development Medicine 52

Scienmag

APRIL 26, 2021

Credit: VCU Massey Cancer Center The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy.

Hormones 92

Hormones Drugs Production Development 92

Medical Xpress

APRIL 26, 2023

A team of researchers at NYU Abu Dhabi (NYUAD), led by Khalil Ramadi, assistant professor of bioengineering at NYU Tandon and the Director of the Laboratory for Advanced Neuroengineering and Translational Medicine at NYU Abu Dhabi, has developed a first-of-its-kind ingestible electroceutical device for the neuromodulation of the gut-brain axis, the (..)

Hormones 75

Hormones Development Research Medicine 75

Scienmag

APRIL 13, 2021

Skoltech researchers have developed a prototype of a fluorescence-based sensor for continuous detection of cortisol concentrations in real time, which can help monitor various health conditions. The paper was published in the journal Talanta.

Hormones 59

Hormones Regulation Development Research 59

Scienmag

APRIL 22, 2021

These results can be used in the development of new cancer treatments, especially for hormone-dependent breast cancer. Researchers in Turku, Finland, have now demonstrated that the activities of distinct Notch family members are modified differently by phosphorylation. Breast cancer is […].

Hormones 75

Hormones Regulation Research Protein 75

ProRelix Research

SEPTEMBER 26, 2023

Endocrine disorders result from the improper functioning of endocrine glands that secrete and regulate hormones responsible for functioning of various organs.

Hormones 52

Hormones Development Regulation Research 52

Scienmag

JUNE 16, 2021

Steroid (sex) hormones play a central role in sexual development: They help determine how boys become boys and girls become girls. If these hormones are disrupted during fetal life, it can lead to a string of reproductive disorders at birth and later in life, including malformed genitals and decreased fertility.

Hormones 45

Hormones Development Medicine 45

Scienmag

SEPTEMBER 15, 2020

Credit: Michigan State University Differences in biological sex can dictate lifelong disease patterns, says a new study by Michigan State University researchers that links connections between specific hormones present before and after birth with immune response and lifelong immunological disease development.

Hormones 78

Hormones Immune Response Development Research 78

Scienmag

DECEMBER 15, 2021

Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world’s largest database of twins.

Hormones 55

Hormones Genetics Development Research 55

The Pharma Data

JUNE 28, 2023

FDA Approves Pfizer’s NGENLA™, a Long-Acting Once-Weekly Treatment for Pediatric Growth Hormone Deficiency NEW YORK & MIAMI–(BUSINESS WIRE)– Pfizer Inc. The approval of NGENLA will be significant for children with growth hormone deficiency in the U.S. NYSE: PFE) and OPKO Health Inc. prescribing in August 2023.

Hormones 40

Hormones FDA Approval Clinical Development Medicine 40

Camargo

NOVEMBER 29, 2021

The development of biological products (or biologics) represents a major advancement in modern medicine, enabling the treatment of patients with many illnesses where no other therapeutics were previously available. Biologics include a wide range of products , including: Vaccines. Blood and blood components. Allergenics. Somatic cells.

Development 180

Development Protein Production Hormones 180

BioSpace

OCTOBER 28, 2020

On October 14th, Amolyt Pharma announced the first dosing in its Phase I trial of AZP-3601 in healthy subjects, a momentous occasion capping off years of hard work in pre-clinical development. The drug aims to walk the biological tightrope in the management of hypoparathyroidism, a rare disease c.

Hormones 59

Hormones Development Clinical Development Trials 59

Scienmag

OCTOBER 21, 2020

Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby’s brain development, a large American study shows. These chemicals, or hormones, are produced in the thyroid gland in the neck and are known to influence fetal growth.

Hormones 66

Hormones Regulation Production Development 66

BioTech 365

SEPTEMBER 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Yeast and bacteria together biosynthesize plant hormones for weed control.Plants regulate their growth and development using hormones, including a group called strigolactones that prevent excessive budding and … Continue (..)

Hormones 40

Hormones Bacteria Regulation Development 40

Scienmag

APRIL 6, 2021

Research provides insight into mechanistic factors that alter hepatic drug disposition during pregnancy Credit: BioIVT BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced that it will be hosting a webinar on April 8 at 11 a.m.

Hormones 53

Hormones Research Drugs Development 53

The Pharma Data

APRIL 28, 2023

FDA approves once-weekly Sogroya® for the treatment of children living with growth hormone deficiency Novo Nordisk announced today that the U.S. years and older who have growth failure due to inadequate secretion of endogenous growth hormone. cm/year vs. 11.7 cm/year, respectively). cm/year vs. 11.7 cm/year, respectively).

Hormones 40

Hormones FDA Approval In-Vivo Production 40

The Pharma Data

JUNE 12, 2022

Investigational phase 3 data for Sogroya ® ( somapacitan ) injection in children with growth hormone deficiency presented today at the ENDO 2022 Congress 1. Based on the results of the REAL 4 study, there is potential for a once-weekly option for children with growth hormone deficiency.”. cm/year, compared to 11.7

Hormones 52

Hormones Medicine Trials Production 52

BioTech 365

APRIL 7, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New biosensor makes control hormone auxin visible in cells.The hormone auxin is of central importance for the development of plants.

Hormones 40

Hormones Scientist Development Research 40

BioTech 365

SEPTEMBER 15, 2021

BIOCORP and MERCK Sign a Partnership in the Field of Human Growth Hormone (HGH) BIOCORP and MERCK Sign a Partnership in the Field of Human Growth Hormone (HGH) Biocorp and Merck will collaborate on the development and global distribution of … Continue reading →

Hormones 52

Hormones Development 52

Pharmaceutical Technology

FEBRUARY 9, 2023

Ibutamoren mesylate is under clinical development by Lumos Pharma and currently in Phase I for Turner Syndrome. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. It is administered orally.

Hormones 100

Hormones Clinical Trials Clinical Trials Genetics 100

Scienmag

NOVEMBER 3, 2020

Cesarean section delivery and vaginal delivery lead to different hormonal exposures that may affect a newborn’s development, according to an article published in the Journal of Neuroendocrinology.

Hormones 40

Hormones Development Medicine 40

Scienmag

SEPTEMBER 27, 2020

Yale physician to discuss the most promising developments in estrogen therapy, including new fetal estrogens, during the 2020 NAMS Virtual Annual Meeting Pre-Meeting Symposium CLEVELAND, Ohio (September 28, 2020)–Hormone therapy remains the best proven method for managing menopause symptoms such as hot flashes.

Hormones 49

Hormones Development Research Cardiology 49

BioTech 365

OCTOBER 6, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: The plant hormone auxin may promote disease by regulating virulence gene expression.Scientists have long known that the plant hormone auxin controls many aspects of plant growth, development, … Continue reading →

Hormones 40

Hormones Gene Expression Regulation Gene 40

Pharma Times

MAY 26, 2023

Therapy has been developed for use among children and adolescents with growth hormone deficiency

Hormones 123

Hormones Development 123

Scienmag

JULY 13, 2022

Researchers have developed a noninvasive method to identify a potential cause of hypertension with a drastic reduction in radiation exposure, a study shows. Around 10-15% cases of hypertension, or high blood pressure, are believed to be caused by excessive production of the hormone aldosterone, which affects the body’s salt-water balance.

Development 58

Development Research Hormones Production 58

Pharmaceutical Technology

FEBRUARY 24, 2023

(LAI-287 + semaglutide) is under clinical development by Novo Nordisk and currently in Phase III for Type 2 Diabetes. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data.

Insulin 182

Insulin Hormones Drugs Clinical Trials 182