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Personalising whole genome sequencing doubles diagnosis of rare diseases 

Drug Discovery World

In 2018, the UK’s department of health announced an NHS Genomic Medicine Service, which allows patients with rare diseases to have their entire genetic code read in the hope of providing a much-needed diagnosis. It can also permit targeted screening of known disease complications and access to drug studies. Context .

Genome 52
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The medical school trying to become anti-racist

The Pharma Data

A major British medical school is leading the drive to eliminate what it calls “inherent racism” in the way doctors are trained in the UK. Exploring the fact that drug trials predominantly involve white, male participants, and looking at how this may lead to inaccurate and harmful prescribing for other patients.

Doctors 52
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Phases of Clinical Research: A Detailed Overview

Advarra

The Importance of Clinical Research in Medical Advancements Researchers use clinical trials to test a drug’s or other medical treatment’s safety and efficacy. Most modern medicines were developed from clinical trials , and clinical trials remain essential for drug development.

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Steps to building a more patient-centric industry

pharmaphorum

According to the FDA’s 2020 Drug Trials Snapshot Report , only 8% of clinical trial participants are Black or African American, as compared to nearly 14% of the US population. The fact is, many minorities never learn about vital clinical trials in play, or that they’re eligible to participate.

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Fatty liver disease: With little early detection, more challenging drug development

pharmaphorum

That was until my doctors stunned me with the news that I had cirrhosis caused by non-alcoholic steatohepatitis, or NASH, a severe form of fatty liver disease that often has few or no symptoms until very late stages. That is a moral failure on the part of medicine. That makes recruitment of patients more challenging.

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Waiver of Informed Consent - proposed changes in the 21st Century Cures Act

Placebo Control

pic.twitter.com/dqmWPpxPdE — Adam Feuerstein (@adamfeuerstein) July 14, 2015 In another tweet, he suggests that the act will "decimate" informed consent in drug trials. Even though the patients aren’t personally identifiable, the collection of medical data qualifies this as a clinical trial.

Trials 40
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Why Black People Remain Underrepresented in Clinical Trials

XTalks

Despite these statistics, in the US, Black people only constitute five percent of all clinical trial participants. The overwhelming majority of trial participants nationwide are white. Race-Based Medicine. Personalized Medicine. However, the links between race-based genetics and disease are not quite clear.