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LNP formulations produce strong immune responses, data shows 

Drug Discovery World

The RNA technology company conducted the work in collaboration with the lab of Professor De Geest at Ghent University, and describes how delivery of mRNA encoded antigens in LNPs comprising a novel class of ionisable lipids enhances the induction of antigen-specific immune responses while reducing undesired off-target expression in the liver, thereby (..)

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Scientists blueprint bacterial enzyme believed to “stealthily” suppress immune response

Scienmag

Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a “stealthy” role in the progression of infection by reducing the immune response.

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mRNA Drugs: Pros, Cons, and Prospects

Pharma Mirror

The first mRNA drug (BNT162b2 vaccine) was granted emergency use authorization by the FDA in December 2020 and approved for marketing in August 2021. The first mRNA drug (BNT162b2 vaccine) was granted emergency use authorization by the FDA in December 2020 and approved for marketing in August 2021.

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Nanoparticles provoke immune response against tumors but avoid side effects

Medical Xpress

Cancer drugs that stimulate the body's immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delivered intravenously, making them harmful to use in patients.

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Potential cancer therapy may boost immune response

Scienmag

The addition of an anti-inflammatory medication to a common chemotherapy drug may improve immune response in patients by activating cells to fight cancer Credit: Cedars-Sinai LOS ANGELES (EMBARGOED UNTIL DEC. 7, 2002 AT 5 A.M.

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Study finds that children’s immune response protects against COVID-19

Scienmag

September 21, 2020–(BRONX, NY)–The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults. The study was published today in Science […].

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Zydus gets FDA approval for antibiotic drug azithromycin

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted final approval to India-based Zydus Lifesciences ‘ 500mg azithromycin tablets for the treatment of bacterial infections. Zydus will manufacture the drug at its formulation facility in Moraiya, Ahmedabad, in the Indian state of Gujarat.