Wed.Oct 14, 2020

Roche, aiming to make better gene therapies, turns to an emerging startup

Bio Pharma Dive

The Swiss pharma is the third large drugmaker to partner with Harvard spinout Dyno Therapeutics, a small biotech aiming to improve gene therapy technology

In the News: September Regulatory and Development Updates

Camargo

Each month, Camargo’s “In the News” series highlights important changes and advancements in the regulatory and development space and explores how those changes could impact your program. FDA Establishes Digital Health Center of Excellence.

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Vertex faces first notable setback as it pushes beyond cystic fibrosis

Bio Pharma Dive

Safety signals in a mid-stage study led Vertex to stop work on one of its experimental drugs for the inherited disorder alpha-1 antitrypsin deficiency

Drugs 198

Eli Lilly Acquires Disarm Therapeutics in an Effort to Solve Axonal Degeneration

BioSpace

Eli Lilly is betting on a new approach to axonal degeneration, announcing a definitive agreement to acquire Disarm Therapeutics, a privately-held biotech company committed to solving this mystery

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FDA approves Regeneron antibody drug as first Ebola virus treatment

Bio Pharma Dive

Research for the drug, now cleared as Inmazeb, helped Regeneron jumpstart its fast development of an antibody therapy for COVID-19

BlueCloud and VirTrial Collaborate to Launch the First Global Training and Certification Program for Telemedicine Best Practices

VirTrial

AUSTIN, TEXAS (PRWEB) OCTOBER 14, 2020.

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Australian research shows NASA’s James Webb telescopes will reveal hidden galaxies

Scienmag

Blinding glare of quasars can be overcome Credit: NASA Two new studies from the University of Melbourne will help the largest, most powerful and complex space telescope ever built to uncover galaxies never before seen by humanity.

J&J’s COVID-19 vaccine trial paused on safety concerns

Pharma Times

Participant in phase III study developed unexplained illness

Are corals genetically equipped to survive climate change?

Scienmag

Credit: This figure appears in the publication in Molecular Biology and Evolution. In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event. From the Great Barrier Reef to Indonesia to Central America, corals turned white and ghostly.

Phase III? What Phase III? Russia Approves Second COVID-19 Vaccine After 100 Person Trial

BioSpace

Putin touts efficacy and safety of new vaccine without the data to back him up

Protein that keeps immune system from freaking out could form basis for new therapeutics

Scienmag

Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction, supports a mechanism critical for survival in mouse models of sepsis and colitis Credit: UC San Diego Health Sciences The immune response to infections is a delicate balance.

Merck Plans New Facility to Triple Production of Life-Saving Bladder Cancer Drug

BioSpace

The pharma giant is currently the only manufacturer of the bladder cancer treatment for the U.S. and Europe

Improving health care autonomy for young adults with autism

Scienmag

MU researcher helps adolescents with autism transition to adult health care Credit: MU School of Health Professions COLUMBIA, Mo. — Independence has always been a driving force in Nancy Cheak-Zamora’s life.

Coronavirus re-infection case confirmed in the US

Pharma Phorum

There is growing evidence that the coronavirus may be able to re-infect patients, and a new instance of a second infection has been confirmed in the US. . It is the fifth confirmed reinfection worldwide after at least four other cases were confirmed in Belgium, the Netherlands, Hong Kong and Ecuador.

Over 150 million websites among a billion tested include sensitive (and tracked) content

Scienmag

Vertex Abandons VX-814 Program for Treating Rare Liver Disease

BioSpace

Vertex Pharmaceuticals announced that after early data on its Phase II trial of VX-814 in Alpha-1 antitrypsin deficiency (AATD), it is halting the trial and ending development of the drug

Oncotarget: Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance

Scienmag

Oncotarget Volume 11, Issue 29 reported that Immunosuppressive chemoresistance is a major burden in lung cancer. Credit: Correspondence to – Savvas Petanidis – spetanid@auth.gr Oncotarget Volume 11, Issue 29 reported that Immunosuppressive chemoresistance is a major burden in lung cancer.

Legal Team for Elizabeth Holmes Fails in Bid to Dismiss Criminal Charges

BioSpace

This week, the judge overseeing her trial denied all efforts from her legal team to dismiss more than a dozen criminal charges against the Theranos founder

Cows prefer “live” co-moo-nication, study reveals

Scienmag

If you’ve ever wondered how to relax a cow, this one’s for you Credit: © Institute of Animal Welfare Science, Vetmeduni Vienna After months of technology-based communication enforced by COVID-19, many of us are missing a “live” human voice.

Eloxx Pharmaceuticals to Report Third Quarter 2020 Financial Results and Provide Business Update on November 5, 2020

The Pharma Data

Company management to host a webcast and conference call to provide a business update and review financial results at 4:30 p.m. WALTHAM, Mass., 15, 2020 (GLOBE NEWSWIRE) — Eloxx Pharmaceuticals, Inc.

Strategic interventions in dairy production in developing countries can help meet growing global demand for milk

Scienmag

Dairy production in developing countries highlighted in November issue of the Journal of Dairy Science® Credit: Adesogan, A.T. and G.E. MILK Symposium Introduction: Dairy production in developing countries. Dairy Sci. 103:9677-9680.

Thermo Fisher Scientific Launches Modular Closed Cell Processing System for Cell Therapy Manufacturing

The Pharma Data

CARLSBAD, Calif. , 15, 2020 /PRNewswire/ — Thermo Fisher Scientific announced the launch of its Gibco CTS Rotea Counterflow Centrifugation System, a modular, closed cell therapy processing system that enables scalable, cost-effective cell therapy development and manufacturing.

Could an existing vaccine make COVID-19 less deadly? Mexico City study provides support

Scienmag

A prospective observational study testing the concept of trained immunity for protection from severe COVID-19 reported milder symptoms in COVID patients receiving MMR vaccination, as published in Allergy.

Seattle Gummy Company Secures The First (IND) Gummy Drug Approval From FDA

The Pharma Data

SEATTLE , Oct.

Mapping out rest stops for migrating birds

Scienmag

New metric can help determine when birds fly over a site or stop to refuel or rest Credit: Colorado State University/ Kyle Horton Each spring, billions of land birds — thrushes, warblers, orioles, tanagers, and more — migrate through the night, navigating the coast of the Gulf of Mexico.

56

VBL Therapeutics Announces Additional New European Patent in the MOSPD2 Platform Technology, This Time for Treatment of Cancer

The Pharma Data

TEL AVIV, Israel, Oct. 15, 2020 (GLOBE NEWSWIRE) — VBL Therapeutics (Nasdaq: VBLT), today announced that the European Patent Office (EPO) has granted Patent # 3328401 , which covers VBL’s proprietary investigational anti-MOSPD2 monoclonal antibodies to treat oncology conditions.

Reviving cells after a heart attack

Scienmag

Armata Pharmaceuticals Announces Clearance of Investigational New Drug (IND) Application to Initiate Phase 1b/2a Clinical Trial of Lead Candidate AP-PA02 in Pseudomonas aeruginosa Infections

The Pharma Data

. MARINA DEL REY, Calif. , 15, 2020 /PRNewswire/ — Armata Pharmaceuticals , Inc.

Tissue grafts of both bone and cartilage could regenerate damage to a crucial jaw joint

Scienmag

Credit: D. Chen et al., Science Translational Medicine (2020) Scientists have engineered tissue grafts that, in pigs, regenerated both bone and cartilage in the temporomandibular joint (TMJ), a part of the jaw that can cause debilitating pain and disability when damaged.

FDA Authorizes Phase 1 Trial of ImmunityBio’s Novel COVID-19 Vaccine Candidate hAd5; Dual Construct is Designed to Drive Both T Cell and Antibody Immunity

The Pharma Data

15, 2020 10:00 UTC. CULVER CITY, Calif.–( –( BUSINESS WIRE )– ImmunityBio, Inc. , a privately-held immunotherapy company, today announced it has received authorization from the U.S.

Researchers mine data and connect the dots about processes driving neuroblastoma

Scienmag

Jude Children’s Research Hospital scientists lead genome analysis to better understand one of the most common childhood solid tumors Credit: St.

VectivBio Closes $110 Million Crossover Financing to Advance Transformational Medicines for Rare Diseases

The Pharma Data

VectivBio’s investor syndicate expands to include Surveyor Capital (a Citadel company), Cormorant Capital and Eventide Asset Management.

Is English the lingua franca of science? Not for everyone

Scienmag

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Harmony Biosciences Receives FDA Approval For Expanded Use Of WAKIX® (pitolisant) For The Treatment Of Cataplexy In Adult Patients With Narcolepsy

The Pharma Data

PLYMOUTH MEETING, Pa. and CHICAGO , Oct.