Fri.Feb 03, 2023

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Magenta to explore sale, merger after study setback

Bio Pharma Dive

The biotech recently stopped a trial of its experimental conditioning regimen over safety concerns. Now it’s halting further development work as it undertakes a strategic review

Sales 314
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HIV vaccines suffer setbacks but new approaches could turn the tide

Pharmaceutical Technology

Only a few weeks into the new year, the prospect of getting a successful advanced HIV vaccine shrank after the discontinuation of yet another late-stage trial. On January 18, Janssen, a Johnson & Johnson (J&J) subsidiary, stated that its vaccine was not effective in preventing HIV infections.

Antibody 284
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COVID-19 vaccine maker Medicago to close down

Bio Pharma Dive

The company, which worked with GSK to develop a coronavirus shot, is ceasing operations after its corporate parent cut off further investment

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Merck reports 2% increase in worldwide sales in Q4 2022

Pharmaceutical Technology

Merck (MSD outside North America) has reported a 2% increase in worldwide sales to $13.83bn in the fourth quarter (Q4) of 2022 from $13.52bn in the previous year’s quarter. The company’s pharmaceutical sales recorded a 1% rise to $12.18bn compared to $12.03bn in the prior-year quarter.

Sales 246
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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

This webinar will go over the FDA's guidance on pharmacological and toxicological considerations for optimizing doses for prescription drugs.

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Roche writes off $3B on lower sales forecasts for gene therapies, cancer drugs

Bio Pharma Dive

Among the drugs Roche recorded impairment charges on are four gene therapies acquired in the company's 2019 deal for Spark Therapeutics

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Modernizing cell culture processes for the next wave of genomic medicine

Pharmaceutical Technology

The field of genomic medicine has reached a true turning point.

Genome 244

More Trending

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US FDA approves Amgen-AstraZeneca’s Tezspire for asthma treatment

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval to Amgen and AstraZeneca ’s Tezspire (tezepelumab-ekko) for self-administration using a single-use, pre-filled pen for severe asthma patients aged 12 years and above.

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J&J's pharma group quietly works through global overhaul, with layoffs expected to reach multiple countries

Fierce Pharma

J&J's pharma group quietly works through global overhaul, with layoffs expected to reach multiple countries mbayer Fri, 02/03/2023 - 09:29

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Range anxiety: Will using predictive technology solve one of the core challenges of EVs? 

Pharmaceutical Technology

For EV drivers, range anxiety – the fear that an EV will run out of available battery charge before reaching its destination – is one of several pain points for the industry.

Pharmacy 130
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Pressure's on, GSK. Merck's Keytruda drops endometrial cancer win in first-line treatment

Fierce Pharma

Pressure's on, GSK. Merck's Keytruda drops endometrial cancer win in first-line treatment aliu Fri, 02/03/2023 - 09:43

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2022 Research: The Rapid Rise of Ocean Freight Visibility

Download this a benchmark study from FourKites and The Journal of Commerce exploring how international shippers’ usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19.

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Price point is a key factor for wider market adoption of Amgen’s Amjevita in the US

Pharmaceutical Technology

Biologic therapies are a mainstay in the management of various immunology indications, including rheumatoid arthritis (RA), psoriasis (PsO), axial spondyloarthritis (axSpA), atopic dermatitis (AD), Crohn’s disease (CD), and ulcerative colitis (UC), and serve as the key growth drivers in terms of commercial value in these indications.

Sales 130
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Cambridge Cognition and Aardex collaborate to boost decentralised clinical trials

Pharma Times

Partnership involves the study of real-time patient data and identification of adherence issues

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Karuna signs licence deal with Goldfinch Bio for TRPC4/5 candidates

Pharmaceutical Technology

Karuna Therapeutics has entered an exclusive licence agreement with Goldfinch Bio for investigational transient receptor potential canonical 4 and 5 (TRPC4/5) channel candidates. Karuna signed the deal with GFB, the assignee of the Goldfinch Bio assignment estate.

Licensing 130
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Green light for AbbVie’s Crohn’s disease therapy Rinvoq

Pharma Times

MHRA approval for Rinvoq which treats adults with moderate to severely active Crohn's Disease

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An Innovative & Creative Problem Solver Approach to Selling in the Medical Device Space

Speaker: Steve Goldstein, Sales Leader

Currently in sales or involved in a business that depends on strong sales results? Join Steve Goldstein, Sales Success Coach, Motivational Speaker and Medical Device Sales Leader from Gold Selling LLC. You will absorb critical strategies to become a trusted partner in greater sales success.

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Mitigating the risks of cross-contamination during Oral Solid Dose (OSD) manufacturing

Pharmaceutical Technology

In 2021, 72% of newly approved drugs were small molecules, and almost 50% of new drugs approved were OSD. While the industry is seeing advances in alternative drug delivery systems, oral solid doses, such as pills, capsules and soft gels, remain at the forefront of the industry.

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With all eyes on new Alzheimer's med, Eisai lays off 91 staffers on its Fycompa team

Fierce Pharma

With all eyes on new Alzheimer's med, Eisai lays off 91 staffers on its Fycompa team fkansteiner Fri, 02/03/2023 - 07:11

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Orserdu (elacestrant) Approved for Patients with ESR1 mutations in ER+/HER2- Advanced or Metastatic Breast Cancers

XTalks

The US Food and Drug Administration (FDA) has approved the first and only oral drug for the treatment of advanced or metastatic breast cancer in postmenopausal women or adult men with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) ESR1 mutations.

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After AbbVie, Teva walks away from influential trade group PhRMA

Fierce Pharma

After AbbVie, Teva walks away from influential trade group PhRMA fkansteiner Fri, 02/03/2023 - 15:53

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Mandatory COVID Vaccination Policy Template

The federal government is developing a rule requiring employers with more than 100 employees ensure their workers are vaccinated or produce a negative COVID test weekly before entering the workplace. So, what can your organization do to prepare? Get Paycor’s COVID Vaccination Policy Template to help communicate important details to your employees.

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Jaypirca (pirtobrutinib) Is Now FDA Approved to Treat Relapsed or Refractory Mantle Cell Lymphoma

XTalks

Loxo Oncology (Eli Lilly and Company) recently announced that their Bruton tyrosine kinase inhibitor (BTKi), Jaypirca (pirtobrutinib), was approved by the US Food and Drug Administration (FDA) to treat adults with relapsed or refractory mantle cell lymphoma (R/R MCL) under the Accelerated Approval pathway.

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Lilly-backed fund commits $24M to Recurv's push for clinical proof of concept of nano-emulsion taxane

Fierce Pharma

Lilly-backed fund commits $24M to Recurv's push for clinical proof of concept of nano-emulsion taxane ntaylor Fri, 02/03/2023 - 07:16

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Navigating One’s Bio-Pharma Career through 2023’s Turbulent Job Markets

Pharmaceutical Commerce

Jasmin Patel of a-Connect provides insight on how to navigate the ebbs and flows of employment.

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Mitsubishi Chemical bids adieu to Medicago—and the company's plant-based COVID shot Covifenz

Fierce Pharma

Mitsubishi Chemical bids adieu to Medicago—and the company's plant-based COVID shot Covifenz fkansteiner Fri, 02/03/2023 - 10:07

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Cell Therapy – The Revolutionary Therapeutic Modality: All Set To Obliterate Oncological Disorders

Roots Analysis

The American Society of Gene and Cell Therapy (ASGCT) defines cell therapy as a therapeutic modality that involves the administration of either normal or modified cells to patients for the treatment of various diseases. In this form of therapy, patients are injected with living and intact human cells that are deemed to be capable of providing therapeutic benefit.

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Gilead spotlights growth for HIV, cancer meds as COVID drug Veklury slides

Fierce Pharma

Gilead spotlights growth for HIV, cancer meds as COVID drug Veklury slides zbecker Fri, 02/03/2023 - 08:44

Drugs 59
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New patent for Salix Pharms drug XIFAXAN

Drug Patent Watch

Annual Drug Patent Expirations for XIFAXAN Xifaxan is a drug marketed by Salix Pharms and is included in one NDA. It is available from two suppliers. There are twenty-seven patents… The post New patent for Salix Pharms drug XIFAXAN appeared first on DrugPatentWatch - Make Better Decisions.

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Vaccines slip, Dupixent climbs for Sanofi as it readies multiple launches in 2023

Fierce Pharma

Vaccines slip, Dupixent climbs for Sanofi as it readies multiple launches in 2023 zbecker Fri, 02/03/2023 - 22:02

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New patent expiration for Endo Pharms drug OPANA ER

Drug Patent Watch

Annual Drug Patent Expirations for OPANA+ER Opana Er is a drug marketed by Endo Pharms and is included in two NDAs. There are eleven patents protecting this drug and six… The post New patent expiration for Endo Pharms drug OPANA ER appeared first on DrugPatentWatch - Make Better Decisions.

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Regeneron plans summer launch for longer-lasting version of Eylea as it tries to fend off rival Roche

Fierce Pharma

Regeneron plans summer launch for longer-lasting version of Eylea as it tries to fend off rival Roche kdunleavy Fri, 02/03/2023 - 11:14

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New patent for Seagen drug TUKYSA

Drug Patent Watch

Annual Drug Patent Expirations for TUKYSA Tukysa is a drug marketed by Seagen and is included in one NDA. It is available from one supplier. There are five patents protecting… The post New patent for Seagen drug TUKYSA appeared first on DrugPatentWatch - Make Better Decisions. Patent Added

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Which pharmaceutical drugs have the most drug patents in Russian Federation?

Drug Patent Watch

This chart shows the drugs with the most patents in Russian Federation. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical drugs have the most drug patents in Russian Federation? appeared first on DrugPatentWatch - Make Better Decisions. Infographic

Drugs 40