Sun.Oct 15, 2023

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World-First Study Finds Immune Cells Crucial to Stopping Bowel Cancer

AuroBlog - Aurous Healthcare Clinical Trials blog

In a medical first, scientists have hindered the growth of bowel cancers in mice by harnessing immune cells in the large intestine. One of the most exciting new cancer treatments is immunotherapy, which works by training the body’s immune system to identify and destroy cancer cells.

Scientist 181
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Lilly’s Tirzepatide Shows Strong Weight Loss Efficacy in Phase III Study

BioSpace

Patients in a late-stage trial treated with Eli Lilly’s GIP and GLP-1 receptor agonist saw a 21.1% mean body weight reduction over 72 weeks following an intensive lifestyle intervention program.

Trials 117
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Indian Pharmacopoeia Commission becomes member of Pharmacopoeial Discussion Group

AuroBlog - Aurous Healthcare Clinical Trials blog

The Pharmacopoeial Discussion Group (PDG), with the Pharmacopoeia Commissions from US, Europe and Japan as members to harmonise pharmacopeial standards globally, has announced the Indian Pharmacopoeia Commission (IPC) as a PDG member.

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Pfizer Kicks Off $3.5B Cost-Cutting Program as COVID Revenues Decline

BioSpace

A revised Paxlovid supply agreement with the U.S. government has pushed Pfizer to launch a “cost realignment” program including layoffs, though it is still unclear how many employees will be affected.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Pfizer launches cost-cutting drive as COVID sales fall

pharmaphorum

Pfizer launches cost-cutting drive as COVID sales fall Phil.

Sales 111
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Novo in $1.3B Deal Buys Late-Stage Hypertension Drug from Singapore Biotech

BioSpace

The Danish pharma announced Monday that it is buying a Phase III hypertension candidate from Singapore-based KBP Biosciences. It is Novo Nordisk’s third high-value purchase in as many months.

Drugs 111

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Experts Implore FDA to Accept Biomarker Evidence in Ultra-Rare Diseases

BioSpace

Last year, the FDA declined to approve a drug that appears to reverse a rare and debilitating enzyme deficiency. Some experts say it’s emblematic of a need for more flexibility around therapeutics targeting rare diseases.

Drugs 98
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Introducing the Guide to Statistics and Methods

JAMA Internal Medicine

The advancement of science and medicine depends on the publication of credible, peer-reviewed evidence. As an integral part of our effort to provide trustworthy evidence, JAMA Internal Medicine is committed to improving the methodological rigor of its publications. As a key part of this effort, every manuscript reporting original research will undergo statistical review before acceptance.

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Opinion: Interest in RNA Editing Accelerates as Therapies Approach the Clinic

BioSpace

The next frontier in RNA therapies, RNA editing has the potential to treat both genetic and common disorders, and the technology is rapidly expanding beyond the liver.

RNA 94
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Attention Millennial Caregivers: Researchers Need Your Help to Develop Mindfulness and Journaling Mobile App!

Trialfacts

Contents About the Study Why Participate? Your Rights Who Can Participate? More Study Details About the Research Center: Research Center: University of Texas at Austin (School of Nursing) Location: This is a nationwide virtual study. Lead Researcher: Megan C. Thomas Hebdon IRB: This study has been reviewed and approved by the University of Texas at Austin Institutional Review Board About the Study Did you know that millennial caregivers are often overlooked when it comes to research and interven

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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FDA Action Alert: Merck, Ardelyx, BioMarin and More

BioSpace

The FDA is gearing up for six decisions in the next two weeks, two of which involve highly anticipated medicines for rare diseases.

Medicine 100
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Optimizing User Experience: Design Principles for Pharma Websites

Pharma Marketing Network

User experience (UX) is an important factor when it comes to website design, and the pharmaceutical industry is no exception. By understanding the principles of UX design, pharma companies can create websites that are optimized for user experience and provide a better overall experience for customers. In this article, we will discuss the principles of optimizing user experience and how to apply them to pharma websites.

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Omeros Shares Plummet on Phase III Kidney Disease Trial Failure

BioSpace

The biopharma discontinued its late-stage study after an interim review found that its investigational treatment for immunoglobin A nephropathy did not achieve statistically significant improvement over placebo.

Trials 55
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SEO Mastery: Optimizing Pharmaceutical Websites for Organic Reach

Pharma Marketing Network

Search Engine Optimization (SEO) is an important tool for any business, but it is especially important for pharmaceutical websites. SEO is the process of optimizing a website for higher organic reach, making it easier for potential customers to find the website. In this article, we will discuss the benefits of SEO for pharmaceutical websites, how to optimize a website for organic reach, and strategies for SEO mastery.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Changes in Care Use and Financial Status Associated With Dementia in Older Adults

JAMA Internal Medicine

This cohort study aims to determine the incremental changes associated with dementia in regard to older adults’ care use as well as assess financial consequences for individuals, families, and society.

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Informa Connect’s PBM Contracting Summit

Drug Channels

Informa Connect’s PBM Contracting Summit December 5-6, 2023 in Chicago, IL Drug Channels readers save 10% with code 23DRCH10 * Join your peers for a unique opportunity to navigate the complex PBM landscape and gain unparalleled strategies to improve patient care and manage costs. The PBM Contracting Summit December 5-6, 2023 in Chicago, focuses on innovative and practical contracting strategies, improving patient care management and rising costs, the current legislative issues impacting contract

Insulin 55
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Ominous Electrocardiogram Changes in a Man With Distal Extremity Weakness

JAMA Internal Medicine

This case report describes a man in his 30s who presented to the emergency department with a sudden onset of distal extremity weakness after waking up 10 hours prior.

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Which pharmaceutical companies have the most lotion dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most lotion dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most lotion dosed drugs… The post Which pharmaceutical companies have the most lotion dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 59
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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Waiting for a Heart Valve

JAMA Internal Medicine

This essay describes a family of physicians waiting for a heart valve for their vivacious 95-year-old aunt.

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