Immuno-Oncology Summit Europe 2023: Programme highlights
Drug Discovery World
JULY 3, 2023
From June 20-22, 2023, Cambridge Healthtech Institute hosted the seventh annual Immuno-Oncology Summit Europe in London.
Engineer Gene Editing In-Vitro In-Vivo 
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Gene editing in organoids: accounting for complexity in drug discovery
Drug Discovery World
JANUARY 12, 2023
The genome is the blueprint for life, consisting of genes made up of thousands of pairs of DNA bases. Altering one base pair can drastically change how the gene’s protein product functions, while mutations can lead to the development of a range of genetic disorders. . What are organoids? .
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What an innovation centre means for 3D biology
Drug Discovery World
NOVEMBER 16, 2022
Think of a cell culture, where scientists can observe the growth of a cell in the body in an in-vitro setting, and gain an understanding of how they react to different drug compounds. Therefore, while researchers can understand just how a drug molecule impacts a cell, they can’t be sure that it will perform the same when used in-vivo. .
Turning science into business: An optimised alternative to antibodies
Drug Discovery World
APRIL 3, 2023
As the industry moves to reduce the use of animals in research and testing, aptamers also support here, as they are discovered, developed, and manufactured entirely in vitro , removing the need for animals in antibody discovery processes. Optimer binders are engineered to overcome these problems. To what do you attribute your success?
ELRIG meeting will focus on genome engineering in drug discovery
Drug Discovery World
DECEMBER 12, 2022
The meeting will focus on the application of genome engineering in identification of novel drug targets through large-scale CRISPR based functional genomics studies, developing advanced cellular and in vivo disease models for target validation, and its applications in therapeutic genome editing. Register here.
The use of base editing in stem-cell based therapies
Drug Discovery World
JANUARY 23, 2023
Kevin Hemphill, R&D Manager at PerkinElmer’s Horizon Discovery explores how base editing has emerged as an attractive gene editing option for researchers wanting to develop stem cell-based therapies. Adult fibroblasts were cultured in a cocktail of transcription factors to reactivate embryonic gene expression patterns 2.
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