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Genetic sleuthing reveals endangered river dolphins in Asia as different species

Scienmag

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction Credit: Mansur/WCR Bangladesh New genetic analysis and years of painstaking research has revealed that one of the world’s most endangered marine mammals is actually two species rather than one, as scientists had long assumed.

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Immunotherapies could target aggressive pancreatic cancer, research indicates

The Pharma Data

Scientists have discovered that hard-to-treat pancreatic cancer hijacks a key immune system response. This damage response is related to a form of programmed cell death that occurs when there’s not enough oxygen – which can happen inside metastatic-like tumours, which tend to be larger in size.

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Beam makes USD 120M bet; GRAIL and Quest announce the collaboration; Brain organoids mimic infant’s brains; Improvement in T cells to kill cancer

Delveinsight

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site.

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Unlocking the potential of mRNA for the future treatment of rare diseases 

Drug Discovery World

As we turn our focus to new potential applications and disease areas for the platform, scientists and companies must consider the potential life-saving impact on rare, inherited diseases, says Archana Gupta , PhD, staff scientist in genetic sciences at Thermo Fisher Scientific.

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AI test could predict best cancer therapies for patients

pharmaphorum

The AI can product response of a tumour to treatment with drugs delivered as single agents or in combination, according to the scientists, who have published their findings in the journal Molecular Cancer Therapeutics.

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Blood Donor Day 2023: Experts weigh in 

Drug Discovery World

BCA members also operate the BCA Advanced Therapies Network which is a diverse, fully integrated portfolio of blood, cell, gene and tissue materials that support the development and delivery of advanced therapies. One example we are following with anticipation are the two FDA approvals for the first gene therapies for sickle cell disease.