pharmaphorum

OCTOBER 3, 2022

Amylyx Pharmaceuticals’ Relyvrio – a new treatment for amyotrophic lateral sclerosis (ALS) approved by the FDA on Thursday, after review of the data from its phase 2 trial – was the next day set at a list price of $158,000 per year in the US, sparking outcry. ALS affects over 30,000 people in the US.

Drugs 52

Drugs Generic Drugs FDA Approval Trials 52

pharmaphorum

OCTOBER 18, 2022

Medtech giant Beckton Dickinson (BD) has signed a deal with France’s Biocorp to use the latter’s near-field communication (NFC) tags in injectable devices. The Injay tag can confirm a complete injection and transfer that information via an NFC reader to a smartphone or tablet for review by a healthcare professional.

Drug Delivery 52

Drug Delivery Drugs Manufacturing Marketing 52

Delveinsight

FEBRUARY 23, 2021

The company plans to use the capital to expand its pipeline of protein-based vaccines and biologic cancer therapies utilizing its innovative and proprietary Trimer-Tag technology platform. BrainStorm Receives Feedback on BLA Submission for ALS. The post Clover biopharmaceuticals raises $230 M; BrainStorm after ALS; BARDA grants $5.65

In-Vitro 52

In-Vitro Vaccination Vaccine Licensing 52

pharmaphorum

OCTOBER 21, 2021

Vounatsos also insisted that Aduhelm’s price tag has not been a factor discouraging treatment with the drug. Biogen stumped up $1.525 billion upfront for rights to the drug and another Sage candidate for neurological diseases last year, when the expectation was that Aduhelm was unlikely to get FDA approval.

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Sales Doctors Doctor Gene Therapy 122

Pharmaceutical Technology

JUNE 29, 2022

The US Food and Drug Administration (FDA) put a high-profile bluebird bio trial for sickle cell disease on partial clinical hold, and advisory panels deliberated over decisions involving gene therapies for amyotrophic lateral sclerosis (ALS), cerebral adrenoleukodystrophy (CALD), and beta-thalassemia.

Drugs 246

Drugs FDA Approval Marketing Development 246

XTalks

OCTOBER 12, 2022

An example of an anti-angiogenic compound working to decrease tumor perfusion is shown by representative images collected by DCE-MRI for a Phase I study ( Figure 1 ); here, the red and yellow areas of the baseline image are areas with very high blood flow, and Liu et al., Figure from Liu et al., Figure from Ricart et al.,

Clinical Trials 93

Clinical Trials Clinical Trials Trials Drugs 93

Drug Discovery World

JANUARY 10, 2023

The principles that have guided our rigorous validation practices for decades preceded a publication (Uhlen et al., Pillar 5: Protein OE/Epitope Tags. Bethyl antibodies are highly regarded for passing strict validation testing before arriving in customer hands. A proposal for validation of antibodies.

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Antibody Protein Reagent Scientist 52