Remove tag economic-impact
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Cost of disease-modifying therapies for multiple sclerosis continues to rise in US

Pharmaceutical Technology

While MS is not a terminal diagnosis, the effect of the disease on the CNS can significantly impact patients’ independence and disturb their daily lives. However, they cannot provide a cure and have a very limited impact on halting disease progression. DMTs for MS have a high price tag, particularly in the US.

Marketing 246
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Chocolate Shortage Looms Ahead of Easter 2024

XTalks

This shortage, attributed to a combination of factors including poor cocoa harvests in West Africa, is poised to impact chocolate lovers worldwide. Climate Change and the Economic Impact Climate change only exacerbates these challenges.

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Grand Rounds September 23, 2022: Effect Of An Intensive Nurse Home Visiting Program On Adverse Birth Outcomes In A Medicaid-Eligible Population (Margaret McConnell, PhD)

Rethinking Clinical Trials

The trial was part of a “Pay for Success” contract that enabled the state to promise funds for further expansion conditional on positive evidence of impact from the randomized trial. The primary evaluation question for the trial was what is the impact of NFP on health outcomes when delivered at scale? Discussion Themes.

Nurses 130
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Upcoming sickle cell gene therapies cost effective at $2 million, says ICER

Pharmaceutical Technology

Two gene therapies up for approval this year for sickle cell disease could be cost effective in some cases at a $2 million price point, based on a draft evidence report published by the Institute for Clinical and Economic Review (ICER).

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Grand Rounds November 17, 2023: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results from the Nudge Study (Michael Ho, MD, PhD; Sheana Bull, PhD)

Rethinking Clinical Trials

Lessons learned: The text message intervention improved medication refill adherence, the effectiveness was consistent regardless of the type of message delivered, and the differential impact of the intervention across some patient groups. The opt out approach is feasible and drop out rate was lower than expected.

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Grand Rounds September 15, 2023: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings (Pasquale Rummo, PhD, MPH)

Rethinking Clinical Trials

The goals of this project were to characterize online food shopping behaviors in an online survey and conduct a randomized clinical trial of behavioral economic strategies on fruit and vegetable purchases in an online grocery store. My thoughts differ for each strategy. I’m a little less interested in the sustainability of those effects.

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Lyfgenia and Casgevy Become First FDA-Approved Gene Therapies for Sickle Cell Disease

XTalks

In a press release , bluebird bio CEO Andrew Obenshain said, “Lyfgenia has the potential to have a transformational impact for patients who currently live under the shadow of unpredictable and debilitating vaso-occlusive events. Vertex-CRISPR’s Casgevy has a US list price of $2.2 million and bluebird’s Lyfgenia is 40 percent higher at $3.1