Clinical Research Informer

Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA)

Rethinking Clinical Trials

JANUARY 31, 2024

The main deliverables for the first phase of the project were developing standard key decision points for the AI product lifecycle and developing the Health Equity Across the AI Lifecycle (HEAAL) Framework. The Health AI Partnership started with 7 organization partners and has expanded to about 20 organizations.

Production

Production Development Clinical Trials Clinical Trials

Grand Rounds August 12, 2022: Equitably Including Diverse Participants in Pragmatic Clinical Trials (Consuelo H. Wilkins, MD, MSCI)

Rethinking Clinical Trials

AUGUST 18, 2022

for Health Equity and Inclusive Excellence. Equity, Diversity, Recruitment. If we are focusing on equity, we need to give participants what they need, such as transit vouchers, childcare considerations, utilizing telehealth, flexible hours, accessible community locations, and compensation. ? ? ? ? ? ? ? ?. Speaker. Consuelo H.

Clinical Trials

Clinical Trials Clinical Trials Trials Insulin

Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. McCreary, PharmD, BCIDP)

Rethinking Clinical Trials

JANUARY 17, 2024

Tags #pctGR, @Collaboratory1 The post Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. We know there is a digital gap in disadvantaged patients and elderly patients. Many patients did not answer the phone.

Clinical Trials

Clinical Trials Clinical Trials Antibody Trials

Grand Rounds July 22, 2022: ACTIV-6: 1-Year Later and Trial Results for Ivermectin-400 and Inhaled Fluticasone (Susanna Naggie, MD, MHS)

Rethinking Clinical Trials

JULY 27, 2022

One thing that has been a struggle is the diversity in the population and the equity in access to trials. We did not see as much diversity in this decentralized trial. Were there concerns about having patients not associated with a site? Learn more about ACTIV-6. pctGR, @Collaboratory1.

Trials

Trials Pharmacy Medicine Clinical Trials

Grand Rounds June 16, 2023: BeatPain Utah: Partnering With Community Health Centers Within a Socio-Technical Framework (Julie Fritz, PT, PhD, FAPTA; Guilherme Del Fiol, MD, PhD)

Rethinking Clinical Trials

JULY 9, 2023

Another crucial element of the health equity–focused model is ensuring that the question at the heart of the research is of value to the clinics and their leadership. For every trial, one of the first important tasks is to reach out to the community health center leadership and see if they are interested.

Clinical Trials

Clinical Trials Clinical Trials Trials Research

IBM sells off large parts of Watson Health business

pharmaphorum

JANUARY 24, 2022

A private equity group has agreed to take over most of IBM Watson Health, seven years after the business was launched with a pledge to revolutionise healthcare data analysis.

Radiology

Radiology Marketing Genome Genomics

Grand Rounds Ethics and Regulatory Series December 9, 2022: The Stepped Wedge Cluster Randomized Trial: Friend or Foe? (Monica Taljaard, PhD; David Magnus, PhD)

Rethinking Clinical Trials

DECEMBER 14, 2022

In a study of more than 100 stepped wedge cluster randomized trials, the most common reason for the design was to be able to make the intervention available to all clusters by the end of the trial based on ethical or equity grounds rather than anything methodological. pctGR, @Collaboratory1.

Trials

Trials Clinical Trials Clinical Trials Medicine

Grand Rounds December 8, 2023: A Pragmatic Randomized Trial of the Jumpstart Intervention to Promote Communication about Goals of Care for Hospitalized Patients with Serious Illness (Ruth Engelberg, PhD; Erin Kross, MD; Robert Lee, MD, MS)

Rethinking Clinical Trials

DECEMBER 12, 2023

Jumpstart may be useful in enhancing equity in serious illness communication among racially or ethnically minoritized patients. Jumpstart provides evidence that a low-touch intervention can nudge clinicians to change behavior. Overall prevalence of goals of care discussions is low suggestions opportunity for improvement.

Trials

Trials Medicine Clinical Trials Clinical Trials

What challenges does the advanced therapies sector face?

Drug Discovery World

JANUARY 30, 2024

Other Challenges: Limited insurance coverage: Many insurance companies are hesitant to cover CGTs due to their high price tags and limited long-term data. Patient access and equity: High costs disproportionately impact access for low-income patients, creating ethical and equity concerns.

Gene Therapy

Gene Therapy Manufacturing Gene Clinical Trials

Grand Rounds September 15, 2023: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings (Pasquale Rummo, PhD, MPH)

Rethinking Clinical Trials

SEPTEMBER 21, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds September 15, 2023: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings (Pasquale Rummo, PhD, MPH) appeared first on Rethinking Clinical Trials.

Clinical Trials

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Oslo Medicines Initiative asks how to balance innovation incentivisation with security of access

pharmaphorum

JANUARY 21, 2022

This evolution is leading to additional health benefits and health gains, but they are accompanied by major concerns, as very high price tags raise questions about their affordability.”. In recent years, revolutionary medicines have come with price tags to match, but this is simply a symptom of our current model. Finding solutions.

Medicine

Medicine Marketing Manufacturing Production

Advanced therapies and the high-profile pricing dilemma

pharmaphorum

NOVEMBER 16, 2022

However, with a price tag of €1.58 However, a recently released report from the organisation could blow the price tag of Zolgensma out of the water. Equity of access. million, the company could not find government and payers ready to meet the cost and chose to withdraw from the European market , rather than lower the price.

Gene Therapy

Gene Therapy Gene Marketing Development

New Rare Disease Drugs and Research Advancements

XTalks

FEBRUARY 27, 2024

Despite high price tags of a couple of million dollars, gene therapy makers say they are working to ensure patients are able to access the treatments through patient assistance programs developed in conjunction with the support of governments. Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial.

Research

Research Drugs Gene Therapy Clinical Trials

Omicron Designated as a Variant of Concern by WHO: What We Know About It So Far

XTalks

NOVEMBER 27, 2021

The technical advisory group on SARS-CoV-2 virus evolution (TAG-VE) met on Friday to discuss B.1.1.529, The appearance of another coronavirus variant further underscores the importance of global vaccination efforts and ties into vaccine equity. 1.1.529, two days after it was first reported to the global health agency by South Africa.

Vaccination

Vaccination Vaccine Protein Scientist

Grand Rounds November 4, 2022: The CardioNerds Clinical Trials Network: Pairing Equitable Enrollment with Trainee Development (Amit Goyal, MD, MAS)

Rethinking Clinical Trials

NOVEMBER 9, 2022

The mission is to democratize cardiovascular education by creating and disseminating education, fostering wellness and humanism, promoting diversity, equity and inclusion, providing mentorship and sponsorship, and invigorating a love of cardiovascular science. We asked site PIs to prioritize nominating fellows who were women and URMs.

Clinical Trials

Clinical Trials Clinical Trials Trials Development

Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. Krumholz, MD, SM)

Rethinking Clinical Trials

OCTOBER 31, 2023

Be welcoming and be authentically committed to health equity and be worthy of the trust. Tags #pctGR, @Collaboratory1 The post Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M.

Trials

Trials Medicine Research Clinical Trials

PFIZER REPORTS STRONG FIRST-QUARTER 2021 RESULTS

The Pharma Data

MAY 4, 2021

Pfizer also made an equity investment of $113 million in BioNTech common stock. Pfizer made an additional investment of $50 million in common stock of BioNTech as part of an underwritten equity offering by BioNTech, which closed in July 2020. Pfizer recorded $1.0 GAAP net income and its components and diluted EPS (1). (3)

Vaccination

Vaccination Vaccine Production Sales

Clinical Research Informer

Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA)

Grand Rounds August 12, 2022: Equitably Including Diverse Participants in Pragmatic Clinical Trials (Consuelo H. Wilkins, MD, MSCI)

Trending Sources

Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. McCreary, PharmD, BCIDP)

Grand Rounds July 22, 2022: ACTIV-6: 1-Year Later and Trial Results for Ivermectin-400 and Inhaled Fluticasone (Susanna Naggie, MD, MHS)

Grand Rounds June 16, 2023: BeatPain Utah: Partnering With Community Health Centers Within a Socio-Technical Framework (Julie Fritz, PT, PhD, FAPTA; Guilherme Del Fiol, MD, PhD)

IBM sells off large parts of Watson Health business

Grand Rounds Ethics and Regulatory Series December 9, 2022: The Stepped Wedge Cluster Randomized Trial: Friend or Foe? (Monica Taljaard, PhD; David Magnus, PhD)

Grand Rounds December 8, 2023: A Pragmatic Randomized Trial of the Jumpstart Intervention to Promote Communication about Goals of Care for Hospitalized Patients with Serious Illness (Ruth Engelberg, PhD; Erin Kross, MD; Robert Lee, MD, MS)

What challenges does the advanced therapies sector face?

Grand Rounds September 15, 2023: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings (Pasquale Rummo, PhD, MPH)

Oslo Medicines Initiative asks how to balance innovation incentivisation with security of access

Advanced therapies and the high-profile pricing dilemma

New Rare Disease Drugs and Research Advancements

Omicron Designated as a Variant of Concern by WHO: What We Know About It So Far

Grand Rounds November 4, 2022: The CardioNerds Clinical Trials Network: Pairing Equitable Enrollment with Trainee Development (Amit Goyal, MD, MAS)

Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. Krumholz, MD, SM)

PFIZER REPORTS STRONG FIRST-QUARTER 2021 RESULTS

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