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Grand Rounds August 25, 2023: Pragmatic Trial of an EHR Application to Display Real-time PRO Data: Successes and Challenges (Gabriela Schmajuk, MD, MS)

Rethinking Clinical Trials

There are 4 components to the treat-to-target approach: record disease activity using a composite measure every 3 months; specify disease activity target; adjust medications to target; and document shared decision making. There are new medications now that were not showing up that required regular updates to the dashboard.

Trials 141
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3 ways pharma marketers can draw inspiration from digitally-native brands

pharmaphorum

“Digitally native brands are typically agile businesses from the ground up, and agility and flexibility are part of their core makeup,” says Joe Holmes, vice president, marketing services, US at Tag. Jeremy Richter, Tag. Joe began his life at Tag in the UK, bringing efficiencies to his clients, working across all conceivable channels.

Branding 128
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After a slow start for expensive CAR-T therapies, drug developers revisit oral therapies for blood cancer

pharmaphorum

Here, Richard Staines reports on phase I/II data unveiled at the American Society of Hematology conference that supports further clinical development of inobrodib in multiple myeloma and other blood cancers. This alone causes expense for cash-strapped hospitals and puts pressure on nursing and medical staff while they manage the side effects.

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Beam makes USD 120M bet; GRAIL and Quest announce the collaboration; Brain organoids mimic infant’s brains; Improvement in T cells to kill cancer

Delveinsight

Earlier, the prescription-only blood test will only be available through partner health systems, medical practices, and self-insured employers. DNA hypomethylating agents are epigenetic drugs that eliminate specific chemical tags on DNA, hence turning specific genes on and off and changing the cells’ function.

DNA 52
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Predicting pandemics with unconventional digital tools

pharmaphorum

Giving the Joseph Leiter lecture at this year’s virtual Medical Library Association (MLA) conference Harvard Medical School’s Professor John Brownstein spoke about embracing non-traditional data streams in public health. Data inadequacies.

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Women in Science Who Have Paved the Way Forward in Genetics

XTalks

In 1951, Franklin joined the Biophysical Laboratory at King’s College, London as a research associate in the Medical Research Council’s (MRC) Biophysics Unit headed by John Randall, where she was made to take up work on DNA after her stints in coal research.

Genetics 119
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AAIC 2021: Six Ways the Approval of Aducanumab Will Change Alzheimer’s Clinical Trials

XTalks

AAt this year’s Alzheimer’s Association International Conference ( AAIC ), entire sessions were dedicated to discussions of Biogen’s recently-approved, controversial drug Aduhelm (aducanumab), but their focus wasn’t what you’d expect. New Alzheimer’s Clinical Trials Will Need to Consider a Combination Design.