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Cartherics grants licence for CTH-004 to Shunxi

Pharmaceutical Technology

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression. The company stated that the agreement structure includes a licence fee, milestone payments, as well as royalties.

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Bristol Myers Squibb pays $475 million for exclusive rights to Dragonfly Therapeutics' IL-12 immunotherapy programme

The Pharma Data

The $475 million price tag on the deal will be made by BMS in near-term upfront payments, and Dragonfly will have access to further milestone payments contingent on regulatory and commercial successes of drugs under the partnership, as well as up to 24% royalties on net sales worldwide. .

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Grand Rounds October 13, 2023: Incorporating Social Determinants of Health Into PCORnet (Keith Marsolo, PhD)

Rethinking Clinical Trials

It is often that you have to take the raw values and harmonize to a particular insurance type (source of payment typology). Tags #pctGR, @Collaboratory1 The post Grand Rounds October 13, 2023: Incorporating Social Determinants of Health Into PCORnet (Keith Marsolo, PhD) appeared first on Rethinking Clinical Trials.

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Grand Rounds December 2, 2022: A Randomized Controlled Trial of Mobile Health Intervention in Heart Failure and Diabetes: Lessons Learned (G. Michael Felker, MD, MHS)

Rethinking Clinical Trials

It was a labor of love; the site payment was low; we asked friends to be sites in the trial. It’s almost always harder in my experience. Sites have a lot of trials that are competing. One pays more than another. We did what we could to make the entry criteria as easy as possible. pctGR, @Collaboratory1.

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Sarepta’s Elevidys Reaches Finish Line as First Gene Therapy Approved for Duchenne Muscular Dystrophy

XTalks

million price tag of Elevidys, a one-time gene therapy. Instead of a treatment outcome-based payment approach that has been adopted by other gene therapies to help with costs, Sarepta is working on “some innovative concepts” with payers, he said. In a media call, Sarepta CEO Douglas Ingram revealed the $3.2

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ICER says bluebird bio’s $2.1m gene therapy is cost-effective

pharmaphorum

million price tag. ” bluebird is proposing that bet-cel will be paid for in five equal payments for patients who achieve and maintain free of transfusions, a goal achieved by 89% of patients in its clinical trials after a median of 42 months’ follow-up.

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What challenges does the advanced therapies sector face? 

Drug Discovery World

 She said: “Payment options will be devised to absorb the costs. One Developing value-based payment models that consider long-term benefits could improve access. Other Challenges: Limited insurance coverage: Many insurance companies are hesitant to cover CGTs due to their high price tags and limited long-term data.