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New 3D maps reveal inner workings of immune cell gene expression

Scienmag

LJI scientists track down control elements that govern gene expression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. “The difference is within us,” says Vivek Chandra, Ph.D.,

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Molecular changes in white blood cells can help diagnose ‘the bends’ earlier in divers

Scienmag

First study to show gene expression changes in divers with ‘the bends’ reveals key role of genes for inflammation and immunity For over a century, researchers have known about “the bends”, a serious condition affecting scuba divers. However, we still know relatively little about its physiological basis.

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Study: Enzyme could prove effective in treating tumors and inflammatory diseases in lung

Scienmag

Histone deacetylases (HDACs) are enzymes that help modulate gene expression by removing […].

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Symvivo’s Oral COVID-19 Vaccine Enters Clinical Trials

XTalks

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We

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New insights into HIV latent cells yield potential cure targets

Drug Discovery World

This technology defines gene expression patterns from rare cells harbouring latent HIV by generating millions of single-cell reaction containers in the form of water-in-oil emulsions, in which messenger RNA capture and virus DNA detection can be performed sequentially while maintaining segregation among cells.

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Nutrigenomics: The Future of Personalized Nutrition

Roots Analysis

At present, extensive studies are being conducted to understand the interaction between nutrients and gene expression at the molecular level, to determine the effect of a specific nutrient and dietary regime on human health. Nutritional DNA testing helps in identifying foods that might lead to allergies or intolerance in an individual.

Genome 40
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Tezepelumab granted Priority Review by U.S. FDA

The Pharma Data

Ann Allergy Asthma Immunol. World Allergy Organization (WAO). EMJ Allergy Immunol. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. Explor Res Hypothesis Med. 2019;4:35-38. Tran TN, et al. 2016;116:37-42. Chung KF, et al. Eur Respir J.