Scienmag

SEPTEMBER 1, 2020

Genetic analysis of sequences from more than 27,000 individuals infected with the coronavirus that causes COVID-19 reveals that the virus has mutated minimally since December 2019, suggesting one vaccine would be sufficient to combat global infections.

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Genetic Analysis Vaccination Vaccine Genetics 70

Scienmag

NOVEMBER 6, 2020

New study demonstrates candidate’s potential to generate antibodies, limit viral shedding Credit: Craig Chandler, University of Nebraska-Lincoln A genetically edited form of a herpes simplex virus — rewired to keep it from taking refuge in the nervous system and eluding an immune response — has outperformed a leading vaccine candidate (..)

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Vaccination Vaccine Immune Response Genetics 49

pharmaphorum

FEBRUARY 28, 2021

The FDA has approved emergency use of a third COVID-19 vaccine from Johnson & Johnson’s Janssen Biotech unit, the day after an advisory committee concluded it was safe and effective. Today, FDA issued an emergency use authorization (EUA) for the third vaccine for the prevention of #COVID19 caused by SARS-CoV-2. Janssen’s Ad26.COV2.S

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Vaccination Vaccine Immune Response Protein 59

pharmaphorum

SEPTEMBER 1, 2020

AstraZeneca has expanded development of COVID-19 vaccine AZD1222 into the US, beginning a phase 3 clinical trial across all adult age groups. Participants are being randomised to receive two doses of either AZD1222 or a saline control, four weeks apart, with twice as many participants receiving the potential vaccine than the saline control.

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Vaccination Vaccine Trials Immune Response 56

The Pharma Data

JANUARY 6, 2021

Rare Vaccination Side Effect in People Who Received Cosmetic Facial Fillers. Food and Drug Administration (FDA) noted that there have been a few reports of people who received cosmetic injections to smooth wrinkles or plump lips having unexpected swelling related to the COVID-19 vaccination. Here’s a look. An update from the U.S.

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Vaccination Vaccine Filler Cosmetics 52

Scienmag

APRIL 10, 2021

[link] New York, NY (April 10, 2021) – A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase (..)

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Vaccination Vaccine Development Clinical Trials 67

Scienmag

SEPTEMBER 11, 2020

Credit: NIAID, 2020 A comprehensive analysis of antibody responses in coronavirus disease 2019 (COVID-19) patients could inform the development of an effective vaccine, according to a study published September 10 in the open-access journal PLOS Pathogens by Chao Wu and Rui Huang of Nanjing University Medical School, and colleagues.

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Antibody Vaccination Vaccine Development 61

The Pharma Data

JUNE 25, 2021

Nasdaq: NVAX), today announced that NVX-CoV2373, its recombinant nanoparticle protein-based COVID-19 vaccine, demonstrated 100% protection against moderate and severe disease, 90.4% “Today, Novavax is one step closer to addressing the critical and persistent global public health need for additional COVID-19 vaccines. Glenn, M.D.,

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Vaccination Vaccine Trials Immune Response 40

Pharmaceutical Technology

AUGUST 5, 2022

But 10% of the cases are caused by genetic factors, meaning patients inherit the condition through familial links. According to Mabbott, a challenge with developing mAbs or vaccines is their potential toxicity. His team is also looking at ways to link the concept of a prion vaccine to a vaccine for Alzheimer’s and Parkinson’s, he adds.

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Drugs Protein Vaccination Vaccine 299

Scienmag

JANUARY 8, 2021

Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells.

Packaging 94

Packaging Packaging Genetics Research 94

Scienmag

DECEMBER 9, 2020

The molecule, known as transmembrane protein 41 B (TMEM41B), is believed to help shape the fatty outer membrane that protects the virus’ genetic material while it replicates […].

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Protein Genetics Allergies Vaccination 75

XTalks

NOVEMBER 30, 2023

This candidate, derived from a person’s own genetically modified cells, aims to restore the Gag-specific CD4+ T cell response in those receiving antiretroviral therapy. Promising HIV Vaccines in Clinical Trials Advancements in preventable therapeutic options for HIV are currently in progress. In November 2023, Hookipa Pharma Inc.,

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FDA Approval Gene Therapy Gene Clinical Trials 109

Scienmag

NOVEMBER 25, 2020

First and corresponding author Dr Lucy van Dorp (UCL Genetics […]. The analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries is published today in Nature Communications.

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Genome Genomics Genetics Research 58

The Pharma Data

MARCH 24, 2021

76% vaccine efficacy against symptomatic COVID-19. Positive high-level results from the primary analysis of the Phase III trial of AZD1222 in the US have confirmed vaccine efficacy consistent with the pre-specified interim analysis announced on Monday 22 March 2021. 100% efficacy against severe or critical disease and hospitalisation.

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Vaccination Vaccine Radiology Trials 52

The Pharma Data

MARCH 13, 2022

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. Singapore biotechnology company. population.

Immune Response 52

Immune Response Protein Medicine Genetics 52

The Pharma Data

MARCH 22, 2021

79% vaccine efficacy at preventing symptomatic COVID-19. The AstraZeneca US Phase III trial of AZD1222 demonstrated statistically significant vaccine efficacy of 79% at preventing symptomatic COVID-19 and 100% efficacy at preventing severe disease and hospitalisation. The trial had a 2:1 randomisation of vaccine to placebo.

Trials 52

Trials Vaccination Vaccine Radiology 52

The Pharma Data

NOVEMBER 17, 2020

Moderna’s COVID Vaccine Shows 94.5% announced on Monday that early results show that its coronavirus vaccine is 94.5 The researchers behind the vaccine said the results were better than they had dared to imagine, though it will probably not be available until spring, the Times reported. effectiveness. percent effective.

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Vaccination Vaccine RNA Allergies 52

The Pharma Data

DECEMBER 31, 2020

Moderna and Pfizer’s COVID-19 Vaccines Roll Out in Early Phase. Food and Drug Administration (FDA) issued Emergency Use Authorization for two COVID-19 vaccines: Pfizer-BioNTech’s BNT162b2 and Moderna’s mRNA-1273. In studies, the vaccines were found to be 94% to 95% effective in preventing COVID-19 disease.

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Vaccination Vaccine FDA Approval Hormones 52

Scienmag

JUNE 25, 2021

The latest in […].

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Immune Response Vaccination Vaccine Protein 75

Scienmag

OCTOBER 9, 2020

Findings could lay the foundation for the development of effective therapeutic and malaria vaccine strategies, which has largely been hindered by a lack of understanding of the host immune response Credit: Aissatou Diawara Abu Dhabi, UAE, October 9, 2020: The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers (..)

Immune Response 52

Immune Response Gene Research Vaccination 52

Scienmag

JUNE 8, 2021

Katalin Karikó receives the 2022 Vilcek Prize for Excellence in Biotechnology for her scientific contributions that led to the development of mRNA vaccines for COVID-19 NEW YORK, June 8, 2021–Dr.

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Vaccination Vaccine Development Research 50

XTalks

DECEMBER 20, 2023

The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy. Bayer’s Astepro (azelastine), an over-the-counter medication for cold, flu and allergies, led the pack in the first half of 2023 with 7.4 billion ad impressions.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

The Pharma Data

FEBRUARY 19, 2022

We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions. For additional information about the company, please visit www.regeneron.com or follow @Regeneron on Twitter. Source link: [link].

Genetics 40

Genetics Antibody Trials Medicine 40

The Pharma Data

FEBRUARY 13, 2022

We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions. For additional information about the company, please visit www.regeneron.com or follow @Regeneron on Twitter. Source link: [link].

Medicine 40

Medicine Genetics Antibody Development 40

Scienmag

OCTOBER 12, 2020

Mouse immune study gives pointers for development of vaccines and immune therapies Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

Gene 40

Gene Vaccination Vaccine Development 40

The Pharma Data

APRIL 13, 2022

“I’m pleased that TAKHZYRO has met these key objectives and I look forward to Takeda sharing further insights with the HAE community in the near future,” said Dr. Marcus Maurer, Professor of Dermatology and Allergy Charité – Universitätsmedizin Berlin, Germany and principal investigator of SHP643-301.

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Dermatology Allergies Genetics Antibody 52

The Pharma Data

MAY 13, 2021

The REAL problem lies in the fact that most of the foods we eat today have been Genetically Modified. Other side effects include food allergy symptoms, increased toxicity, negative reproductive effects, negative effects to digestive systems, unknown genetic effects on humans and EVEN DEATH (rats and mice).

Production 52

Production Containment Genetics Doctors 52

XTalks

DECEMBER 24, 2020

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. For example, investment in mRNA vaccines and viral vectors came well before January, many years before it.

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Scienmag

FEBRUARY 23, 2021

Viruses make copies of themselves during an infection, and new research sheds light on one of the coronavirus molecules that is important for this process, providing a potential drug target that could work for Covid-19 and other coronavirus outbreaks too. Credit: Image courtesy of Keith Mickolajczyk.

Drugs 61

Drugs Research Allergies Genetics 61

Scienmag

NOVEMBER 24, 2020

Credit: Salk Institute LA JOLLA–(November 24, 2020) Salk Professors Susan Kaech and Alan Saghatelian have been named 2020 Fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the journal Science.

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Allergies Gene Genetics Vaccination 62

Scienmag

SEPTEMBER 15, 2020

Molecular clock analysis showed no widespread ‘community’ distribution of the highly contagious coronavirus disease in Arizona until mid-February FLAGSTAFF, Ariz. — Sept.

Genome 40

Genome Genomics Allergies Genetics 40

The Pharma Data

JANUARY 27, 2021

27, 2021 — New and more infectious coronavirus variants are beginning to appear in the United States, but all have remained vulnerable to the two vaccines now being distributed to Americans, the White House COVID-19 Response Team said Wednesday. WEDNESDAY, Jan. The South African variant, which has yet to reach U.S.

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Vaccination Vaccine Antibody Allergies 52

Scienmag

DECEMBER 22, 2020

Around a third of the world’s population carries Toxoplasma gondii, a parasite that puts people with a weakened immune system at risk and can trigger malformations in the womb. The single-celled pathogen also leads to economic losses in agriculture, with toxoplasmosis increasing the risk of abortion among sheep, for example.

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Genetic Engineering Engineer Genetics Allergies 40

The Pharma Data

DECEMBER 18, 2020

Food and Drug Administration said Thursday night that it will move quickly to authorize the emergency use of Moderna’s coronavirus vaccine after one of its advisory panels voted to give its blessing to the shot. “Following today’s positive advisory committee meeting outcome regarding the Moderna COVID-19 vaccine, the U.S.

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Vaccination Vaccine Trials Scientist 52

The Pharma Data

MAY 13, 2021

May 13, 2021 – Johnson & Johnson (NYSE: JNJ) (the Company) today announced the World Health Organization (WHO) and the government of Sierra Leone have begun administering the Company’s Ebola vaccine regimen as part of a WHO early access clinical program aimed at preventing further spread of Ebola in West Africa. NEW BRUNSWICK, N.J.,

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Vaccination Vaccine Medicine Clinical Trials 52

The Pharma Data

DECEMBER 31, 2020

million doses of the approved Pfizer and Moderna COVID-19 vaccines had been distributed across the United States by Monday morning, just 2.1 That’s far too slow a pace, said one official charged with spearheading the vaccination of Americans. million vaccination tally — compiled by the U.S. . THURSDAY, Dec.

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Vaccination Vaccine Genetics Protein 52

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. Tension is mounting as nations big and small jockey around industry to ensure they are first in line to access a vaccine, should one prove to be successful against COVID-19. Moderna’s COVID-19 Vaccine. The price of that prize is incalculable.

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Vaccination Vaccine Antibody Life Science 68