The Pharma Data

JULY 21, 2021

This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi , the bacteria that cause Lyme disease. OspA is one of the most dominant surface proteins expressed by the bacteria when present in a tick.

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Pfizer

FEBRUARY 16, 2023

This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi, the bacteria that cause Lyme disease. OspA is a surface protein expressed by the bacteria when present in a tick. FDA in July 2017.

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Drug Discovery World

DECEMBER 14, 2023

In November 2023, University of Glasgow and University of Oxford spin-out Glox Therapeutics raised £4.3M ($5.2M) in seed funding to develop targeted therapeutics against antibiotic-resistant Gram-negative bacteria. Another BioCity tenant, BioAscent provides science-led integrated drug discovery services.

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Drugs Life Science Research Scientist 75

The Pharma Data

OCTOBER 26, 2020

AR-711 is a fully human immunoglobulin 1, or IgG1, monoclonal antibody discovered from screening the antibody secreting B-cells of convalescent COVID-19 patients. He will address the preclinical performance of AR-711, the advantages of direct lung delivery using nebulized aerosols, and the COVID-19 clinical program. About AR-711.

Antibody 52

Antibody Genetic Engineering Development Licensing 52

XTalks

DECEMBER 17, 2021

As Moderna’s first ever commercial product, the company wasn’t positioned for large-scale manufacturing of its COVID-19 Spikevax vaccine. Initial lab studies, including one from South Africa, show that vaccine-induced antibodies may be less effective at neutralizing Omicron.

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Life Science Vaccination Vaccine Trials 98

Drug Discovery World

AUGUST 10, 2022

Next, the advent of antibody treatments in 1997 created the first targeted cancer therapy 2. And as researchers study all of these factors, they are also discovering that CAR T cell development and manufacturing require a new approach to quality control to ensure their safety and efficacy. The challenge of manufacturing CAR T cells.

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Manufacturing Gene Genome Genomics 98

XTalks

AUGUST 2, 2023

Most of the company’s revenue comes from the manufacture and sale of biopharmaceutical products. every eight weeks for the 90 mg dose, according to the manufacturer. First FDA-approved in July 2017 for plaque psoriasis, the list price for a 30-day supply of Tremfya was stated to be $6,292, according to the manufacturer.

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Sales Manufacturing FDA Approval Life Science 98

Drug Discovery World

APRIL 25, 2024

Cell line development is an essential underpinning of the drug development process, enabling teams to test, optimise and manufacture therapeutics at a commercial scale. For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in.

Development 59

Development Protein In-Vivo Life Science 59

The Pharma Data

OCTOBER 19, 2020

Results from both studies are based on opsonophagocytic activity (OPA) responses – a measure of vaccine-induced functional antibodies. There are more than 90 different types of pneumococcal bacteria which can affect adults differently than children. Food and Drug Administration before the end of the year, remain on track.

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Vaccination Vaccine Immune Response Containment 52

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. Membrane Filters: Membrane filters are typically used for sterilization and removal of smaller impurities such as bacteria and viruses. are used to remove any residual bacteria, viruses, or endotoxins.

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Bacteria Production Contamination Protein 40

The Pharma Data

DECEMBER 2, 2020

aeruginosa bacteria, instead of killing the bacteria as an antibiotic would aim to do. Tubulis – Germany’s Tubulis formed a strategic collaboration with WuXi STA and WuXi Biologics to manufacture and advance Tubulis’ next generation antibody-drug conjugates (ADCs) towards IND-enabling studies. in Mainland China.

Drugs 52

Drugs Gene Editing Genome Genomics 52

XTalks

AUGUST 18, 2021

Also important are the environmental changes that take place in the lung tissue during infection with SARS-CoV-2; the buildup of fluid and pus in pulmonary alveoli can provide a hospitable breeding ground for pathogenic bacteria. This is consistent with autopsy reports from previous pandemics, including the influenza pandemic of 1918.

Development 105

Development Bacteria Drugs Vaccination 105

XTalks

APRIL 12, 2021

Though the company expected to begin enrollment into a sham-controlled EXPLORE-PD Phase II trial this year, manufacturing delays experienced by its CDMO partner Oxford Biomedica have made it unlikely that this AXO-Lenti-PD study will begin by the end of 2021. Research suggests that some gut bacteria can increase levels of ?-synuclein

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Gene Therapy Gene Trials Development 96

The Pharma Data

OCTOBER 14, 2020

The AOP Orphan Group manufactures 80% of its drugs in Europe and has more than 20 subsidiaries and representative offices across the whole of Europe as well as in the United Arab Emirates and Israel. The funds will be used to bring Ori’s innovative manufacturing platform to the market. million if certain project milestones are met.

Clinical Trials 52

Clinical Trials Clinical Trials Manufacturing Trials 52

XTalks

DECEMBER 24, 2020

Distilleries and breweries used their production facilities to make hand sanitizers while car manufacturers such as GM, Ford and Tesla, and vacuum maker Dyson , pledged to convert their assembly lines to make ventilators. Most antibody drugs and vaccines have been developed to target parts of the spike protein. Drug Approvals.

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The Pharma Data

MAY 14, 2021

Charles River loses a battle over harvesting horseshoe crabs used for testing bacteria in drugs ( STAT ). Delayed second Pfizer COVID-19 shot produces more antibodies -study ( Reuters ). Delayed second Pfizer COVID-19 shot produces more antibodies -study ( Reuters ). Medtech.

Gene Therapy 52

Gene Therapy Gene Vaccination Vaccine 52

Pharmaceutical Technology

MAY 17, 2023

In addition to revolutionising diabetes care, insulin has become an essential component of biopharmaceutical manufacturing, where its growth-supplementing ­­­properties are relied on to enhance commercially available cell culture media and achieve higher yields of target therapeutic proteins. Can it support the newer therapeutic modalities?

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Insulin Production Manufacturing Contamination 130

Pharmaceutical Technology

MARCH 24, 2023

TB is caused by the bacillus Mycobacterium tuberculosis and is transmitted when infected individuals expel bacteria into the air (e.g., However, the vaccine is less effective in those who already have viral antibodies present in their blood, leaving out a large proportion of people. by coughing). million new cases reported worldwide.

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Vaccination Vaccine Clinical Trials Clinical Trials 162

Pharmaceutical Technology

DECEMBER 15, 2022

It is important that preservatives do not compromise the quality or performance of a formulation or product but simply protect it against microbial proliferation throughout the entirety of the product’s manufacture, shelf life, and usage. There are many other aspects to take into consideration. It has proved to be most effective at high pH.

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