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Innovative Nipocalimab Trial for HDFN Treatment Powered by BillionToOne

XTalks

BillionToOne, a company specializing in molecular diagnostics, has partnered with Janssen Research & Development, LLC, a Johnson & Johnson division, to conduct the AZALEA Phase III clinical trial globally. Nipocalimab is an investigational monoclonal antibody that targets the neonatal Fc receptor.

Trials 97
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What Innovative Treatments For Metastatic Breast Cancer are being developed?

Find Me Cure

If you follow our blog you know that we at FindMeCure take updating our readership on treatments in development very seriously. This Breast Cancer Awareness Month we’d like to talk about emerging areas in metastatic breast cancer treatment since clinical research has come so far in recent years.

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Eight announcements to expect at AACR 2023   

Drug Discovery World

BDC-3042 is an agonistic antibody targeting Dectin-2, an immune-activating receptor expressed by TAMs. Tumour-associated macrophages (TAMs) are an abundant immune cell population in many solid tumours and play a key role in establishing the immunosuppressive tumour microenvironment that enables tumour progression.

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Where is the drug discovery expertise happening in the UK?

Drug Discovery World

Alchemab, on the other hand, has developed a highly differentiated platform which enables the identification of novel drug targets and therapeutics by analysis of patient antibody repertoires, drawing from the expertise in Cambridge to progress the company’s mission to build a broad pipeline of protective therapeutics for hard-to-treat diseases.

Drugs 75
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The Utility of Liquid Biopsy in Oncology Clinical Trials

XTalks

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. Another method to isolate CTCs is by antibody targeting of white blood cells for removal, followed by collection of untagged CTCs.

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News from AACR 2024: Wednesday’s highlights

Drug Discovery World

On the final day of AACR, the plenary session of the Annual Meeting put artificial intelligence at the forefront and featured a stellar lineup of AI and data science experts who discussed AI and topics such as imaging, precision medicine, and drug development.

HR 52
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Avoiding Radiation Toxicity: Understanding Dosimetric Endpoints and Challenges in Radiopharmaceutical Clinical Trials

XTalks

Radiopharmaceutical therapy (RPT) uses isotopes that are conjugated to tumor-targeting agents (such as peptides, antibodies and novel small molecules). Radionuclide-ligand conjugates, including radionuclides that are conjugated to antibodies or peptides, have been studied extensively. How does Radiation Cause Cell Death?