Drug Discovery World

APRIL 30, 2024

Its job is to carry coding information that is essential to the translation and processing of functional proteins. This is essential to its use as a therapeutic agent and gives the technology a vast versatility making it suitable to treating a wide range of diseases – especially those that have high protein expression.

RNA 52

RNA Protein Vaccination Vaccine 52

XTalks

NOVEMBER 9, 2021

Ever since pesticides became widely used in agriculture, scientists have been searching for ways to improve upon pest protection for both human and planetary health. RNA interference (RNAi) is one such improvement that earned the scientists responsible for its discovery a Nobel Peace Prize in 2006. In 2017, Monsanto Co.

RNA 98

RNA Gene Scientist Protein 98

Drug Discovery World

AUGUST 10, 2022

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells. Identifying the right CAR T cell target.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Drug Discovery World

MAY 2, 2023

The CRISPR-Cas9 system, awarded the Nobel Prize in Chemistry in 2020 for its applications for gene editing, was initially encountered in the bacterial immune system. Today, scientists leverage this defence mechanism to learn more about the genomic alterations in diseased states as well as the impact of drug treatments on the human genome.

Genome 52

Genome Genomics Gene DNA 52

XTalks

FEBRUARY 11, 2021

Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Martha Chase: For the Books. Martha Chase. The marriage ended in divorce after a few short years.

Genetics 119

Genetics DNA Genome Genomics 119

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. To address these issues, scientists and clinicians are starting to look at ‘long-read’ sequencing.

Genome 118

Genome Genomics Medicine Gene 118

Drug Discovery World

OCTOBER 4, 2022

Rebecca McClellan, Scientific Program Manager, Research, Development & Communications, explains how scientists are learning more about the connections between the microbiome and human health to potentially develop first-in-class microbiome therapies. They introduced hCom1 to mice that are carefully designed to have no bacteria present.

Research 52

Research Bacteria Scientist Bacterium 52

Drug Discovery World

JULY 18, 2023

Since its discovery in 2012, CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionised the biomedicine and cell and gene therapy fields, providing a versatile tool for precise and efficient genome editing. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g.,

DNA 98

DNA Genome Genomics RNA 98

The Pharma Data

JANUARY 21, 2021

They found an unusual result—the most frequently mutated ALS genes found in general populations were typically not affected in Malta ALS patients. Specifically, the Malta patients did not have mutations in the C9orf72, SOD1, TARDBP and FUS genes. It also reversed age-related mental decline in older mice.

Research 52

Research DNA Hormones Vaccination 52

XTalks

AUGUST 2, 2023

Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease. Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

XTalks

DECEMBER 24, 2020

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.

Life Science 111

Life Science Vaccination Vaccine Gene 111

The Pharma Data

MAY 14, 2021

Charles River loses a battle over harvesting horseshoe crabs used for testing bacteria in drugs ( STAT ). COVID-19 lab leak theory cannot be ruled out, leading scientists say ( Reuters ). COVID-19 lab leak theory cannot be ruled out, leading scientists say ( Reuters ). Medtech.

Gene Therapy 52

Gene Therapy Gene Vaccination Vaccine 52

Pharmaceutical Technology

MARCH 24, 2023

TB is caused by the bacillus Mycobacterium tuberculosis and is transmitted when infected individuals expel bacteria into the air (e.g., Fox, the principal scientist behind the trial, says this is an important development in TB vaccine research as the current BCG vaccine must be refrigerated. by coughing).

Vaccination 162

Vaccination Vaccine Clinical Trials Clinical Trials 162