The Pharma Data

JULY 11, 2021

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. In doing so, they induce epigenetic changes.

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pharmaphorum

NOVEMBER 10, 2021

Success, then, will rely on an integrated response that focuses on surveillance, stewardship, and intervention accessibility across the spectrum of human, animal, and environmental health, said the report, which was commissioned to assess the progress of the 2014 National Strategy for Combating Antibiotic-Resistant Bacteria. Surveillance.

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Drug Discovery World

MAY 6, 2024

Although a smaller country in terms of population size, Switzerland’s pharmaceutical production value is larger than Germany’s and Ireland’s combined 1. Start-ups will also take candidates from the pharma companies that are not getting attention for one reason or another and develop those into viable commercial products.”

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Drugs Life Science Gene Editing Gene 59

Drug Discovery World

JULY 26, 2023

With 100-fold the number of genes in the human genome 1 , this microbial collection is a rich genetic signature of clinical significance that we have only recently gained the tools to explore. Genome editing tools such as CRISPR may be employed to create “live biotherapeutics” (drugs composed of living bacteria).

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Medicine Genome Genomics Bioinformatics 52

The Pharma Data

JANUARY 19, 2021

A naturally occurring system for tuning CRISPR-Cas9 expressing in bacteria, identified in a study published in Cell , could have implications for gene editing therapies as well. In bacteria with unaltered tracr-L, levels of CRISPR-related genes were low. The authors found that tracr-L redirects Cas9 in S.

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Bacteria Gene Editing Research RNA 52

Drug Discovery World

AUGUST 10, 2022

By Mark White, Associate Director of Biopharma Product Marketing at Bio-Rad and Marwan Alsarraj, Biopharma Segment Manager, Digital Biology Group. The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force.

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Manufacturing Gene Genome Genomics 98

Drug Discovery World

APRIL 25, 2024

CHO cells are typically used for the large-scale production of monoclonal antibodies (mAbs) and recombinant proteins since their ability to grow and divide rapidly under controlled bioreactor conditions makes them suitable for higher yields when producing therapeutics proteins.

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Development Protein In-Vivo Life Science 59

XTalks

DECEMBER 17, 2021

billion because of delays in regulatory authorizations/approvals, production and supply chain deliveries as well as global export bans. As Moderna’s first ever commercial product, the company wasn’t positioned for large-scale manufacturing of its COVID-19 Spikevax vaccine. However, it had to pare down that goal by 25 percent to 1.4

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The Pharma Data

DECEMBER 2, 2020

aeruginosa bacteria, instead of killing the bacteria as an antibiotic would aim to do. Vivlion holds an exclusive license to Goethe University of Frankfurt’s proprietary 3Cs technology for the production of next generation 3Cs CRISPR/Cas gRNA libraries. Financial details of the agreement were not disclosed. in Mainland China.

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Drugs Gene Editing Genome Genomics 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g., CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg.

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DNA Genome Genomics RNA 98

Drug Discovery World

NOVEMBER 18, 2022

A review of the antibacterial products in preclinical development by the WHO 3 shows that only 30% of research is coming from medium or large companies. The researchers discovered Dynobactin, an antibiotic that can kill Gram-negative bacteria, which can be responsible for causing infections such as pneumonia and bloodstream infections.

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Bacteria Drugs Development Research 52

Drug Discovery World

APRIL 30, 2024

Their functions such as carrying oxygen, providing structural support to cells, transmitting biological processes to cells, and fighting viruses and bacteria, are essential to human health. If the body fails to make the right protein, diseases such as cancer, type II diabetes, neurological conditions, and metabolic diseases can occur.

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RNA Protein Vaccination Vaccine 52

Drug Discovery World

MAY 4, 2023

The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target. The drug target for Penicillin is a protein that helps bacteria to synthesise its cell wall. Salvarsan was soon overtaken by the Penicillin antibiotics.

Medicine 52

Medicine Protein Drugs Bioassay 52

XTalks

DECEMBER 24, 2020

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. Infectious disease expert, epidemiologist and director of the Yale Institute for Global Health at Yale University, Saad B.

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Life Science Vaccination Vaccine Gene 111

The Pharma Data

OCTOBER 14, 2020

ERS Genomics – Ireland’s ERS Genomics signed an agreement with FASMAC Co., has expanded its product portfolio to include Blueprint, a self-service, scientific visualization and analytics application for small molecule discovery. The patent is valid through 2038. Ltd of Japan. million if certain project milestones are met.

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