pharmaphorum

MAY 27, 2022

This is the second in a two-part series examining how pharma can embrace the DEI agenda to create more effective medicines through more representative clinical trials. The same principles are increasingly being applied to clinical trials to improve diversity, mitigate bias, and reinforce inclusion in clinical trials.

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pharmaphorum

OCTOBER 20, 2021

A software platform developed by Altoida that uses augmented reality and artificial intelligence to diagnose neurological diseases in their earliest stages is being tested in a five-year trial involving thousands of patients.

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Trials Genome Genomics Bioinformatics 78

Drug Discovery World

OCTOBER 20, 2023

The latest acquisitions and strategic partnerships in the drug discovery and development sector reveal the areas where companies predict significant growth in the near future: proteomics, CAR-T, antibody discovery, artificial intelligence (AI) and microbiomics. We aim to continue to ‘open up’ the druggable antibody space.”

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Drugs Antibody DNA Gene Therapy 52

STAT News

MARCH 6, 2023

Unlike most people who receive medications yet to be cleared by the Food and Drug Administration, none of these patients is getting the vaccines as part of a clinical trial. Instead, the 26 patients paid the foundation to create the vaccines and provide them through the FDA’s expanded access program.

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Scienmag

MAY 19, 2021

Proprietary bioinformatics, paired with comprehensive clinical curation results in reporting that defines clinically actionable, FDA-approved, and clinical trial drug options for the management of the patient’s cancer.

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XTalks

NOVEMBER 7, 2022

Gleich, MD, FACS, Senior Vice President, Medical Department, and Dr. Christopher Huth, PhD, Senior Clinical Trial Manager, Clinical Trial Management. Liquid Biopsy Use in Oncology Clinical Trials. Optimal methods for bioinformatic analysis are still needed. percent show less reliability).

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Clinical Trials Clinical Trials Trials FDA Approval 98

Drug Discovery World

MAY 1, 2024

Many of the best-selling drugs in 2023 were monoclonal antibody (mAB) therapies, including Keytruda (pembrolizumab), Humira (adalimumab), and Dupixent (dupilumab) 1. Ben Holland, Co-Founder and CTO of Antiverse, notes that AI and machine learning now touch 10% of drug discovery projects.

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Antibody FDA Approval Drugs Development 59

Drug Discovery World

JULY 27, 2023

In a DDW Sitting Down With podcast with Lu Rahman, Ruth Roberts and Claire Sadler , ApconiX, discuss the benefits of performing a target safety assessment (TSA) during drug discovery and development when a biological target is going to be acted on by a drug. Over 40% of drug safety failures are due to the drug target.

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pharmaphorum

APRIL 1, 2021

AI simulated cell company Turbine is just one of many digital drug discovery firms on the rise in Hungary. We speak to the company’s CEO and co-founder, Szabolcs Nagy, to find out why moving beyond traditional biotech drug development is a good fit for the country’s ecosystem. They go into bioinformatics”. So what do they do?

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Bioinformatics Drugs Development Scientist 123

Scienmag

NOVEMBER 9, 2020

Credit: Insilico Tuesday, November 10, 2020 (9AM Beijing) – Insilico Medicine, a leader in deep generative reinforcement learning for target discovery, small molecule generation, and prediction of clinical trial outcomes, today announced that it entered into a multi-target drug discovery agreement with Janssen Pharmaceutica N.V.

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Drug Discovery World

SEPTEMBER 14, 2023

Enabling the discovery and development of novel mRNA-based cancer vaccines by leveraging Moderna’s knowledge of mRNA science and customised information from Immatics’ wealth of tumour and normal tissue data, which is included in XPRESIDENT, the company’s target discovery platform, and XCUBE, the company’s bioinformatics and AI platform.

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Drug Discovery World

JULY 11, 2023

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. How AI and ML are influencing drug development Biopharma has experienced significant growth in using these technologies for the past 10 years.

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Drug Discovery World

NOVEMBER 7, 2022

They subsequently applied additional bioinformatic approaches, using advanced computer technologies to identify genetic alterations in a patients’ DNA which may be causing disease but had been overlooked during routine testing. . It can also permit targeted screening of known disease complications and access to drug studies.

Genome 52

Genome Genomics Genetics Genetic Disease 52

Drug Discovery World

APRIL 6, 2023

These topics will be represented across a range of session types, including methods workshops, minisymposia, poster and plenary sessions, as well as keynotes, awards and lectures.

Protein 52

Protein Clinical Trials Clinical Trials Antibody 52

The Pharma Data

DECEMBER 8, 2020

9, 2020 /PRNewswire/ — United Therapeutics Corporation (Nasdaq: UTHR) announced today that the United States Food and Drug Administration (FDA) has granted orphan drug designation to treprostinil for the treatment of patients with idiopathic pulmonary fibrosis (IPF). SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C. ,

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Drug Discovery World

APRIL 18, 2023

would not have qualified for genetic screening under current guidelines, according to results from the Tapestry clinical trial presented at AACR 2023 today. The post Tuesday 18 April at AACR Annual Meeting 2023 appeared first on Drug Discovery World (DDW). Read more here. Read more about AACR award winners here.

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Genetics DNA Research Bioinformatics 52

Drug Discovery World

OCTOBER 7, 2022

This would need to be investigated in future clinical trials. In order to find the right targets for drug developments, it’s important to have a deep understanding of the complex mechanisms that allow some cancer cells to resist treatment, then hide from our immune system to only re-emerge later when they’re harder to eradicate.

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Research Immune Response Gene Bioinformatics 52

XTalks

MAY 20, 2022

They also assist in the testing of medical devices and development of drug products. Here is a summary of the kind of work you can expect to do: Design and implement clinical trials for human diseases and treatment. Their work might involve matching blood samples for transfusions. Liaise with stakeholders and scientists.

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The Pharma Data

SEPTEMBER 1, 2020

.–( BUSINESS WIRE )– Bristol Myers Squibb (NYSE:BMY) today announced interim results from the Phase 3 open-label extension trial DAYBREAK, demonstrating the long-term efficacy and safety profile of Zeposia (ozanimod) in patients with relapsing forms of multiple sclerosis (MS). of participants in the trial, respectively.

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Trials Clinical Trials Clinical Trials Vaccination 52

Drug Discovery World

OCTOBER 25, 2023

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development. I’m not so sure. DG : For sure!

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Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

JULY 26, 2023

This leap in understanding, which has been facilitated by the emergence of next generation sequencing (NGS) technologies and bioinformatics tools such as artificial intelligence (AI), has brought forward a new wave of precision medicine resources, diagnostics, and therapeutics specifically aiming to leverage the microbiome.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

pharmaphorum

APRIL 15, 2021

“When the pandemic struck, we pivoted basically overnight to integrate many remote and digital processes – things like preparing submission dossiers remotely, but also decentralised clinical trials which are more patient-centric as the trial revolves around the patient and not the test center. In principle, this goes beyond medicines.

Development 76

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Drug Discovery World

APRIL 14, 2023

He is being recognised for illuminating research contributions to defining the links between chromosomal abnormalities and cancer, including his discovery of TMPRSS2-ETS gene fusions in prostate cancer, and for pioneering the use of pathological and bioinformatic methodologies to diagnose and track prostate cancer onset and progression.

Genetics 52

Genetics Research Medicine Clinical Research 52

The Pharma Data

JULY 27, 2021

Teneobio’s discovery platform, TeneoSeek, comprises genetically engineered animals (UniRat® and OmniFlic®), next-generation sequencing, bioinformatics and high-throughput vector assembly technologies. Food and Drug Administration, and no conclusions can or should be drawn regarding the safety or effectiveness of the product candidates.

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Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care. It also helps to quickly address unplanned changes.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

XTalks

APRIL 21, 2023

Biotech company Ultima Genomics has joined forces with Genome Insight, a bioinformatics-based biomedicine company, to overcome the caveat of cost and quality in WGS. Ultima Genomics will provide their high-throughput NGS instrument platform, the UG 100, and Genome Insight will provide the bioinformatics platform for data analysis.

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XTalks

DECEMBER 13, 2023

The company’s sustained investment in R&D has led to a rapid expansion of its pipeline in 2023, with notable milestones such as four infectious disease vaccines in Phase III trials, including the recently submitted respiratory syncytial virus (RSV) vaccine for regulatory approval. million and $38.8 million and $33.9

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Drug Discovery World

JULY 19, 2023

The tide has been turning in the worlds of diagnostics and drug development. Bioinformatics and genetic sequencing are starting to be placed front and centre of public research programmes as scientists from around the world recognise the substantial benefits of knowledge sharing and resource pooling when it comes to genetic science.

Genome 52

Genome Genomics Bioinformatics Genetics 52

pharmaphorum

SEPTEMBER 14, 2020

If you are developing a drug, for example, for infantile epilepsy, then you need to know if your drug target is expressed in the brain and also during early development. Likewise, some patients may have a different version of a gene with respect to people on whom a drug has been tested, which means that drug might not work.”.

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Genome Genomics Medicine Gene 119

XTalks

SEPTEMBER 5, 2023

Investigation of the possibility of VAED is crucial during clinical trials for decision-making on vaccine licensing by regulatory agencies. In the majority of cases, the risk of VAED is brought to light during preclinical stages or early clinical trial phases.

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Vaccination Vaccine Development Clinical Trials 96

Drug Discovery World

NOVEMBER 30, 2023

This conditional activation is intended to focus immune attack more specifically against tumour cells and minimise damage to healthy cells, a major challenge for current oncology drugs and development efforts. The post Reflecting on PEGS Europe 2023 appeared first on Drug Discovery World (DDW).

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The Pharma Data

OCTOBER 27, 2020

The growth in Orenitram revenues resulted primarily from an increase in quantities sold, as the number of patients being treated with Orenitram grew following the update to Orenitram’s labeling to reflect the FREEDOM-EV clinical trial results, partially offset by the impact of the Excess Order. Expenses.

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The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. They tell you, ‘that’s a drug that saves us from the coronavirus.’

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pharmaphorum

MARCH 28, 2022

AION Labs’ third call for applications seeks computational biologists, bioinformatics and cheminformatics scientists, AI researchers, and antibody or protein engineers at academic and industry research labs worldwide to assemble a fully funded start-up company.

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