Drug Discovery World

MARCH 21, 2023

The work promises to reduce the threats of viral contamination when harnessing bacteria to produce medicines such as insulin as well as other useful substances, such as biofuels. coli to make all their life-sustaining proteins from 61 sets of genetic building blocks, or codons, instead of the naturally occurring 64.

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Engineer Genetic Engineering Scientist Bacteria 52

XTalks

JULY 25, 2023

Kelly Warfield, Emergent’s senior vice president, science and development, in the company’s press release. While there is no evidence of person-to-person transmission, anthrax skin lesions may be contagious through direct contact or contaminated objects. What Is Anthrax? Anthrax is a rare, yet severe disease caused by the bacterium B.

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Drug Discovery World

FEBRUARY 28, 2023

With only 10% of these conditions indicated for an approved therapy, there is a sizable opportunity for scientists and companies to develop treatments for patients with no other options to turn to. At this stage, qPCR can be used to check for IVT efficiency, residual DNA contamination and adventitious agents such as microbes.

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Genetics Genetic Analysis Vaccination Vaccine 52

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. It involves the separation of unwanted particles from biological materials to obtain contaminant free products. For example, ultrafiltration retains proteins, allowing other molecules to pass through.

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Drug Discovery World

NOVEMBER 1, 2023

Ruizhi Wang, Chief Executive Officer of Abselion will explain how the company’s Amperia benchtop instrument can be used for protein quantifaction and binding assay. Wang will also discuss the automation and compatibility features of the instrument.

Life Science 52

Life Science Contamination Gene Therapy Manufacturing 52

Drug Discovery World

MAY 11, 2023

Kerstin Pohl , Senior Global Marketing Manager, Gene Therapy & Nucleic Acid at SCIEX, looks at the application of liquid chromatography-mass spectrometry for analysing host cell proteins. Host cell proteins (HCPs) – proteins derived from the host cells used for viral production—are one class of process-related impurities.

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Production Gene Protein Vaccination 52

XTalks

NOVEMBER 18, 2021

The brand’s products are packed with 14 grams of protein, prebiotics and 21 different organic ingredients, including kale and mushrooms. Related: Better Bagel: The Low-Carb, High-Protein Bagel That’s “Changing the Grain”. In fact, the company developed more than 1,000 versions of noodles to get the taste and consistency just right.

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Branding Protein Contamination Marketing 98

Pharmaceutical Technology

APRIL 16, 2023

This is an exciting prospect: oncology, and immuno-therapy in particular, is a driving force behind biotech R&D, with new cancer therapies and molecules accounting for nearly 40% 1 of the industry’s development pipeline. mL devices – all of which are developed by SHL Medical. To learn more, download the document below.

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Protein Containment Drug Delivery Drugs 130

Roots Analysis

OCTOBER 24, 2023

Different Types of HPAPIs The new generation of APIs being developed are highly complex in nature, including peptides, HPAPIs, oligonucleotides and sterile APIs. The ADCs bind to specific proteins or peptides in cancer cells with very high specificity and efficacy influencing the biological functions.

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Manufacturing Hormones Contamination Containment 40

Roots Analysis

MAY 24, 2024

In addition, various combination products have been approved / are currently under development for the treatment of various therapeutic indications, such as rheumatoid arthritis, diabetes, psoriasis, psoriatic arthritis and multiple sclerosis. This is extremely important for injectable medications.

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Drug Delivery Containment Contamination Production 40

XTalks

AUGUST 7, 2023

Ycanth (cantharidin) topical solution, developed by Verrica Pharmaceuticals Inc., This condition is marked by the appearance of small, raised lesions known as mollusca, which usually develop on the body. Immunocompromised individuals are particularly vulnerable to complications and may develop larger lesions.

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FDA Approval Dermatology Trials Clinical Trials 98

Drug Discovery World

AUGUST 10, 2022

And as researchers study all of these factors, they are also discovering that CAR T cell development and manufacturing require a new approach to quality control to ensure their safety and efficacy. Developing the first CAR T cell therapy. These treatments have shown success in treating a variety ofcancers 4.

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Manufacturing Gene Genome Genomics 98

Pharmaceutical Technology

MAY 17, 2023

In addition to revolutionising diabetes care, insulin has become an essential component of biopharmaceutical manufacturing, where its growth-supplementing ­­­properties are relied on to enhance commercially available cell culture media and achieve higher yields of target therapeutic proteins. One big challenge is contamination.

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Insulin Production Manufacturing Contamination 130

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. The threat of empty capsids Capsids are the protein shell that would usually enclose the genetic material of a virus. What makes an ideal AAV analytics tool for process development?

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

Roots Analysis

OCTOBER 24, 2023

The limitations of stainless-steel bioreactors such as high risk of contamination, process related challenges and high operational cost have prompted innovators to develop more advanced single use bioreactor in order to meet the rising demand for safe and efficacious biotherapeutics.

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Pharmaceutical Technology

JULY 22, 2022

However, the development added to the concerns of increased monkeypox outbreaks in both the US and Canada, while confirmed cases have been reported from both Spain and Portugal, the article highlighted. Long-term infections can cause damage to the liver and kidneys, and can cause infertility and bladder cancer.

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Vaccination Vaccine Life Science Immune Response 130

Drug Discovery World

FEBRUARY 2, 2023

Bryan Oronsky , Chief Development Officer at EpicentRx, discucsses how one drug sourced from the defense and aerospace industry, could have many potential disese targets. A late-stage clinical trial in head and neck cancer for the treatment of severe oral blistering or oral mucositis caused by radiation therapy is planned.

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Manufacturing Clinical Trials Clinical Trials Drugs 52

XTalks

FEBRUARY 8, 2024

Ozempic (Semaglutide) Ozempic sales in 2022: $8.713 billion Company/Developer: Novo Nordisk Date of first FDA approval: December 5, 2017 Indications Ozempic is FDA-approved for: Type 2 diabetes Price of Ozempic: $1,029 for 1.5 Trulicity (Dulaglutide) Trulicity sales in 2022: $7.439 billion Company/Developer: Eli Lilly & Co.

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Sales Insulin FDA Approval Drugs 52

XTalks

NOVEMBER 7, 2022

However, Dr. Bahassi reported that the selection of CTCs using this method is often not very efficient and the CTC population is usually highly contaminated with leukocytes. During the webinar, Dr. Bahassi gave a brief schematic of how personalized, targeted assays can be developed to detect somatic mutations from cfDNA ( Figure 1 ).

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Clinical Trials Clinical Trials Trials FDA Approval 98

XTalks

MAY 13, 2022

This involves careful selection and development of packaging systems with considerations of stability, storage, accelerated aging, freeze-thaw, altitude, drop, vibration distribution simulation, as well as identification and characterization of compounds released from packaging materials (i.e. shaking, changes in pressure, etc.).

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Packaging Packaging Containment Production 98

The Pharma Data

MAY 4, 2021

to $3.65, Primarily Reflecting Updates to Anticipated Contributions from BNT162b2 Partially Offset by Additional R&D Expenses for Vaccines to Protect Against COVID-19 as Well as Other mRNA-Based Development Programs and COVID-19 Antivirals. Raises Full-Year 2021 Guidance (3) for Revenues to a Range of $70.5 previously $59.4

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Vaccination Vaccine Production Sales 40

XTalks

SEPTEMBER 14, 2020

And in truth, the companies the White House picked were pretty savvy as several are current front-runners in the race to develop a vaccine. The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. helped protect COVID-19 patients against developing severe disease.

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Vaccination Vaccine Antibody Life Science 92