Drug Discovery World

JANUARY 23, 2024

” The ability to collect and analyse such a new wealth of ocean data comes from major developments in DNA sequencing technology and computational power. The post World’s largest catalogue of ocean DNA could boost drug discovery appeared first on Drug Discovery World (DDW).

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Medical Xpress

NOVEMBER 18, 2022

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

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Outsourcing Pharma

SEPTEMBER 8, 2023

A benchtop DNA sequencer developed by the U.S. DNA sequencing company Element Biosciences, Inc., has seen sales grow by triple digits and has received more than 100 orders since its launch in March 2022.

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Bio Pharma Dive

DECEMBER 12, 2023

Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.

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Outsourcing Pharma

JULY 18, 2023

company KSQ Therapeutics to co-develop KSQâs lead cancer drug, which is designed to sabotage the DNA repair mechanisms of cancer cells. Roche has entered a licensing and collaboration deal with the U.S.

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Medical Xpress

FEBRUARY 22, 2023

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

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Outsourcing Pharma

MAY 25, 2023

A company developing small molecule therapeutics targeting DNA Damage Response (DDR) in order to treat patients with a broad range of cancers has its first assay development customer.

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Scienmag

APRIL 7, 2022

Chemists integrated computer functions into rolling DNA-based motors, opening a new realm of possibilities for miniature, molecular robots. Nature Nanotechnology published the development, the first DNA-based motors that combine computational power with the ability to burn fuel and move in an intentional direction.

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Pharma Times

OCTOBER 5, 2023

It will be the company’s first platform to be installed in an external scientific setting - News - PharmaTimes

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Medical Xpress

NOVEMBER 17, 2022

BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop.

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Scienmag

JULY 19, 2022

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate.

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Outsourcing Pharma

DECEMBER 23, 2020

The analytical tool, developed via Bionano Genomics, maps structural variations in DNA that are known to cause disease and are tied to symptom severity.

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Scienmag

MAY 2, 2022

WINSTON-SALEM, NC – May 2, 2022 — Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases.

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Scienmag

DECEMBER 28, 2021

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as […].

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Pharmaceutical Technology

JUNE 8, 2023

Biotechnology company Hopewell Therapeutics has raised $25m in seed financing to accelerate the development of next-generation lipid nanoparticles for targeted delivery of genomic medicines. Hopewell Therapeutics is engaged in discovering, synthesising and developing advanced ttLNPs to provide next-generation genomic medicines.

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BioPharma Reporter

OCTOBER 5, 2023

Researchers from Chung-Ang University, Korea have developed a novel DNA biosensor which could result in early diagnosis of cervical cancer.

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Pharmaceutical Technology

APRIL 4, 2023

Evergreen Discovery has partnered with Orbit Discovery to discover specific cell-targeting peptides and advance the development of new radiopharmaceuticals. The Orbit platform will also conduct in vitro transcription conversion from DNA-encoded libraries on beads.

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Pharmaceutical Technology

APRIL 4, 2024

The vaccines will be developed using Touchlight’s doggybone DNA technology, which speeds up the manufacturing process.

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BioPharma Reporter

FEBRUARY 6, 2023

AstraZeneca has cut the cost and time needed to complete DNA synthesis by integrating an assembly framework into Benchling.

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Pharmaceutical Technology

JULY 19, 2023

The Phase I trial evaluates the combination Telix’s targeted radiation therapy with Merck’s peposertib, a DNA-PK Inhibitor.

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Medical Xpress

MAY 4, 2023

In a study of 17 people from five families, Johns Hopkins Medicine researchers say they found that ultra-lengthy DNA endcaps called telomeres fail to provide the longevity presumed for such people.

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Drug Discovery World

APRIL 19, 2023

Scientists at The Institute of Cancer Research, London, are teaming up with small molecule neoantigen immuno-oncology company NeoPhore to develop new potential cancer drugs. Image: Human breast cancer cells stained for DNA (red). New treatments aim to take advantage in cancer cells’ DNA repair mechanisms.

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Drug Discovery World

JULY 19, 2022

Non-coding or ‘junk’ DNA could contribute to the development of certain cancers due to how it disrupts the replication of the genome, scientists have discovered. . A team from The Institute of Cancer Research (ICR), London reconstituted the entire process of DNA replication in a test tube in order to understand it more completely.

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pharmaphorum

AUGUST 23, 2021

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

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Medical Xpress

MARCH 23, 2023

DNA is our body's instruction manual. It contains all the information that our cells need to make proteins and other molecules vital for our development, growth and survival.

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BioPharma Reporter

OCTOBER 5, 2021

VGXI, Inc, a provider of plasmid DNA manufacturing and development services, says multiple construction milestones have been reached for its new headquarters and manufacturing facility in Texas.

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BioPharma Reporter

AUGUST 2, 2021

With Scancell taking its DNA-based COVID-19 vaccine tech into clinical trials this year, it is already focusing its attention on the techâs potential to be used as a needle-free booster shot to address Variants of Concern.

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Medical Xpress

NOVEMBER 15, 2022

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential implications for preventing the development of cancer in patients with these mutations.

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Roots Analysis

JUNE 1, 2022

DNA cloning is the field of synthetic biology which can be helpful to understand the effect of mutation on a particular gene. Many diseases that can be treated using DNA cloning, such as leukemia and sickle cell anemia, involving the replacement of defected gene. DNA Cloning Kit Providers – Current Market Landscape.

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Scienmag

MAY 3, 2021

Detection innovation could enhance drug development and cancer research Credit: Richard Hooley/UCR Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they’ve been extremely difficult to detect — until now.

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Pharmaceutical Technology

MARCH 24, 2023

Moderna has entered a strategic partnership with Generation Bio for the development of non-viral genetic medicines. The collaboration aims to expand each company’s platform application through the development of new nucleic acid therapeutics, and to expedite their respective non-viral genetic medicines pipelines.

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Scienmag

JUNE 23, 2022

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.

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BioTech 365

DECEMBER 6, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: High-resolution mapping method for G4 DNA structures developed.While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for … Continue reading → (..)

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pharmaphorum

DECEMBER 3, 2020

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The principle of DNA damage response is already being exploited by AstraZeneca and other companies with their poly (ADP-ribose) polymerase (PARP) inhibitor drugs.

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pharmaphorum

OCTOBER 19, 2023

Innovative biopharma including BioNTech, Genentech, AskBio, Pfizer, Roche, Sanofi and more will unite in Boston

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Roots Analysis

DECEMBER 12, 2021

DNA data storage involves encoding and decoding binary data to and from synthesized strands of DNA. DNA data storage is an innovative technology that works by encoding large digital data sequences of binary form (0s and 1s) into DNA sequences (Adenine (A), Guanine (G), Cytosine (C) and Thymine (T)). DNA Storage.

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BioSpace

MARCH 2, 2021

GE Research selected DNA Script to join a collaboration working on a rapid response, mobile platform to develop on-demand production of nucleic acid-based vaccines and therapies related to biological threats.

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