Worldwide Clinical Trials

FEBRUARY 6, 2023

The best course of action will depend on many variables, such as the disease or population being studied and the genotype/phenotype relationship, risk, and impact on care. Obtaining appropriate assistance to facilitate planning up front for the complexities involved will save sponsors time and effort in the long run. Read the full article!

Genetics 130

Genetics Clinical Trials Clinical Trials Genotype 130

Scienmag

AUGUST 25, 2020

Credit: Iliana Baums, Penn State Coral conservation efforts could get a boost from a newly developed genotyping “chip”–the first of its kind for corals.

Genotype 66

Genotype Genetics Development Research 66

pharmaphorum

OCTOBER 9, 2020

Most experience some form of cognitive difficulty, and some develop psychosocial problems related to short stature and feelings of social isolation. We are not aware of so many aspects of this disease because they have not been researched adequately,” she says. The physical impact of Aarskog is extremely wide ranging.

Research 111

Research Genetics Genotype Nurses 111

Pharmaceutical Technology

DECEMBER 15, 2022

Since HFC replacement therapy is the mainstay of treatment for CFD, increased development of more innovative fibrinogen-based therapies will benefit both the CFD population and patients experiencing AFD. CFD is an extremely rare disease in which many patients are often asymptomatic and do not require treatment.

Marketing 130

Marketing Production Genotype Development 130

pharmaphorum

JANUARY 21, 2022

A third dose of vaccine has been shown to effectively neutralise the Omicron variant of covid-19, according to researchers. Research led by UCLH, UCL and the Francis Crick Institute found that the booster dose successfully stimulates antibody levels that neutralise Omicron. Details of the study were published in The Lancet this week.

Antibody 115

Antibody Vaccination Vaccine Genotype 115

pharmaphorum

JANUARY 24, 2023

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

Genetics 98

Genetics Drugs Genome Project Biobanking 98

Delveinsight

DECEMBER 13, 2020

Due to hepatitis C, most people develop cirrhosis, or scarring of the liver, before liver cancer; about 5–25% of patients with chronic hepatitis C develop cirrhosis over 10–20 years. Research and development in Hepatitis. In contrast, approximately 850,000–2.2 Hurdles in the Hepatitis treatment. Pegylated INF-?2b

Genotype 52

Genotype FDA Approval DNA Drugs 52

Drug Discovery World

MAY 22, 2023

Not-for-profit medical research organisation LifeArc and techbio company PrecisionLife have agreed a strategic R&D collaboration to accelerate the discovery of targeted treatments for motor neurone disease (MND). LifeArc researchers will lead and coordinate target validation and drug discovery projects.

Medicine 52

Medicine Genotype Genetics Clinical Trials 52

Roots Analysis

APRIL 28, 2024

However, the rising incidence and prevalence of rare kidney disease, with poor outcomes and high cost has led to an increased research activity in this domain. Such obstacles lead to the limited use of such mouse models for development of rare kidney disease drug.

Genetics 40

Genetics Genotype Development FDA Approval 40

Drug Discovery World

FEBRUARY 27, 2024

DDW Editor Reece Armstrong speaks to Ron Alfa , CEO & Co-founder at NOETIK, about the company’s mission to utilise artificial intelligence (AI) and spatial biology to develop better immunotherapies for cancer patients. Reece A: What are some of the human limitations to current drug discovery research for immunotherapies?

Genome 52

Genome Genomics Genotype Medicine 52

XTalks

MARCH 29, 2021

According to a study by researchers at the National Institutes of Health (NIH), moderate caffeine intake could lead to small babies. The research found that even consumption of less than the recommended moderate amount of 200 mg of caffeine per day for adults, which is about two cups of coffee, posed an increased risk to the fetus.

Genotype 98

Genotype Allergies Hormones Research 98

The Pharma Data

NOVEMBER 18, 2020

18, 2020 — Genetic variants in some patients with inflammatory bowel disease (IBD) are associated with a significantly increased risk for developing thromboembolic disease (TED), according to a study published online Oct. The researchers found that 122 of 792 IBD patients (15.4 WEDNESDAY, Nov. 21 in Gastroenterology.

Genetics 52

Genetics Genotype Genome Genomics 52

The Pharma Data

SEPTEMBER 8, 2021

TIB Molbiol excels in ultra-rapid assay development for emerging infectious disease, strongly demonstrated during the COVID-19 pandemic. The acquisition enables Roche to further expand the portfolio of currently over 45 CE-IVD assays and more than 100 research use assays on Roche`s LightCycler PCR instruments. About TIB Molbiol.

Genotype 52

Genotype Reagent Genetics Research 52

Advarra

FEBRUARY 28, 2023

In an effort to accelerate the sharing of biomedical research results, the National Institutes of Health (NIH) issued its finalized Data Management and Sharing (DMS) policy , effective January 25, 2023. The policy statement supported reusing existing scientific data and accessibility of high value datasets for use in future research studies.

Research 52

Research Genome Genomics Genotype 52

Drug Discovery World

SEPTEMBER 20, 2022

The results were presented at the ME Genetics Research Summit organised by ME charity, Action for ME and the MRC Human Genetics Unit, University of Edinburgh. . The study also identified similarities with genes that are believed to be associated with multiple sclerosis (MS) and long Covid.

Genetics 52

Genetics Biobanking Genotype Gene 52

The Pharma Data

NOVEMBER 2, 2020

(NASDAQ:ADIL; ADILW) , a clinical-stage biopharmaceutical company focused on the development of treatments for addictions, today provided an update on its landmark ONWARD Phase 3 pivotal trial. Adial Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the development of treatments for addictions.

Trials 52

Trials Genotype Marketing Production 52

XTalks

FEBRUARY 4, 2021

Data generated through high-throughput omics approaches paired with clinical patient records can give rise to remarkably robust datasets to inform and guide disease insights and development of targeted therapeutics. Generation of strong research dataset cohorts must begin with high-quality clinical samples.

Research 98

Research Biobanking Drugs Genome 98

The Pharma Data

MARCH 16, 2022

Roche and its subsidiary, Tib Molbiol, confirm that it has tests for research use that identify the SARS-CoV-2 subvariants of concern, Omicron: BA.1, It’s critical to quickly and accurately identify variants to inform ongoing research – including the ongoing development of therapeutics and vaccines.

In-Vitro 52

In-Vitro Genotype Reagent Protein 52

Drug Discovery World

NOVEMBER 23, 2023

Artificial Intelligence (AI) has become a popular buzzword in the drug discovery and development lexicon but not all approaches to AI-driven drug discovery produce meaningful insights that translate into real compounds which ultimately demonstrate clinical efficacy in human trials.

Biobanking 59

Biobanking Drugs Medicine Genome 59

pharmaphorum

NOVEMBER 10, 2021

“Better estimates of the burden of antimicrobial resistance in humans and animals depend on better microbiological data and more clarity on the appropriate design of epidemiological research. This database should support automatic importation from hospitals, laboratories and surveillance networks and link to genotypic data when available.”.

Medicine 106

Medicine Genome Genomics Genotype 106

XTalks

APRIL 29, 2021

While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. Proviral DNA Genotyping.

DNA 98

DNA Drugs RNA Genotype 98

XTalks

JANUARY 22, 2021

Taiwan-based health and biotech company MedFluid has developed a rapid automated bacterial identification screening tool that can also tailor antibiotic treatments to an infection. It identifies bacteria using both genotypic and phenotypic assessments within 1.5

Bacteria 52

Bacteria In-Vitro Genotype Marketing 52

The Pharma Data

NOVEMBER 10, 2020

Biomarkers will be critical to developing precision medicine for Alzheimer’s disease. Although a few are out there, phosphorylated tau (P-tau) may enable even earlier and more accurate detection, according to Eli Lilly-associated researchers speaking at the Clinical Trials on Alzheimer’s Disease (CTAD) virtual conference in early November.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Antibody 52

XTalks

SEPTEMBER 28, 2020

The test was developed by Resolution Bioscience and the company will run test analyses in its labs. The Resolution ctDx Lung assay was developed to offer patients and clinicians with pertinent information that can inform treatment decisions. Related: Liquid Biopsies Help Match Cancer Patients to Phase I Trials.

Gene 105

Gene DNA Life Science Genotype 105

XTalks

MARCH 3, 2021

BridgeBio is dedicated to developing therapies for genetic diseases with unmet needs. BridgeBio said in an announcement that the novel therapy was developed based on “BridgeBio’s commitment to developing a treatment for MoCD Type A in collaboration with the experts and families in the MoCD Type A community.”

FDA Approval 64

FDA Approval Genotype Clinical Trials Clinical Trials 64

XTalks

APRIL 15, 2021

Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. The reverse could also be true whereby the development of coronary artery disease may impact heart rate. HFrEF vs. HFpEF.

Development 98

Development Drugs Genome Genomics 98

The Pharma Data

DECEMBER 9, 2020

Uniquely positioned in the rapidly evolving local biotech ecosystem in China in addition to an expansive global presence, Overland will strategically partner to jointly develop innovative, novel therapeutics. We look forward to developing and advancing our differentiated pipeline of novel therapeutics in carefully selected disease areas.”.

In-Vivo 52

In-Vivo In-Vitro Antibody Development 52

The Pharma Data

DECEMBER 9, 2020

Liebisch , Vigil Neuroscience is developing a pipeline of precision-based therapies to combat both rare and common neurodegenerative diseases by restoring the vigilance of microglia. It will if the following five companies, which all launched this year with Series A financing, have anything to say about it. . Vigil Neuroscience.

Marketing 52

Marketing In-Vivo Protein In-Vitro 52

The Pharma Data

NOVEMBER 18, 2020

To coordinate the global effort to protect the long-term efficacy of HIV medicines, WHO, in collaboration with HIVResNet, a global HIV resistance network, developed an HIV drug resistance prevention and assessment strategy. WHO has developed survey methods to monitor pretreatment HIV drug resistance. governance and enabling mechanisms.

Drugs 52

Drugs Genotype Medicine Development 52

Drug Discovery World

FEBRUARY 9, 2024

DDW recently hosted a webinar ‘Discover how iPSC derived cells can be used to support the development of drug and gene therapies’, supported by DefiniGEN. Chris explained that DefiniGEN is a liver cell company focussed on hepatocytes, particularly supporting the drug development industry in producing liver therapies. Watch on demand.

Gene Therapy 52

Gene Therapy Gene Development Drugs 52

Drug Discovery World

SEPTEMBER 5, 2023

This system allows researchers to investigate the effect of the treatment on the target protein, but the cellular environment bears little resemblance to that of the human liver, an impediment to reliable compound triaging. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

Development 59

Development Drugs Protein Genotype 59

Drug Discovery World

SEPTEMBER 26, 2023

This system allows researchers to investigate the effect of the treatment on the target protein, but the cellular environment bears little resemblance to that of the human liver, an impediment to reliable compound triaging. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

Development 52

Development Drugs Protein Genotype 52

XTalks

APRIL 24, 2023

“Rare disease clinical trials are complex due to the additional scientific, medical, operational and regulatory requirements of newly emerging advanced therapies, such as gene therapy,” says Dr. Terence Eagleton, MB BS, Senior Medical Director at the global clinical research organization (CRO) Medpace.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

Drug Discovery World

SEPTEMBER 19, 2023

This system allows researchers to investigate the effect of the treatment on the target protein, but the cellular environment bears little resemblance to that of the human liver, an impediment to reliable compound triaging. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

Gene Therapy 52

Gene Therapy Gene Development Protein 52

Drug Discovery World

SEPTEMBER 12, 2023

This system allows researchers to investigate the effect of the treatment on the target protein, but the cellular environment bears little resemblance to that of the human liver, an impediment to reliable compound triaging. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

Gene Therapy 52

Gene Therapy Gene Development Drugs 52

Delveinsight

AUGUST 25, 2021

The pharmaceutical industry finds, develops, manufactures, and promotes medicines or pharmaceutical drugs for usage as medications that are administered (or self-administered) to patients in order to cure, vaccinate, or relieve symptoms. billion in research and development. The global healthcare spending in 2020 was USD 8.3

Vaccination 98

Vaccination Vaccine Sales Drugs 98

Pharmaceutical Technology

AUGUST 18, 2022

0 genotypes. After more than a decade of research and clinical development, and through the perseverance of clinicians, patients and their families, the approval of Zynteglo marks a watershed moment for the field of gene therapy.”. Findings showed that 89% of evaluable subjects attained transfusion independence (TI).

Gene Therapy 246

Gene Therapy Gene Genotype Genetics 246