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COVID prompts another milestone, as India clears first DNA vaccine

pharmaphorum

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

DNA 98
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Opinion: Where are the guidelines for the production of animals with intentional genomic alterations?

STAT News

Genetic engineering has the potential to transform how we raise animals for meat and other products, making food safer, improving animal health and welfare, and shrinking animal agriculture’s environmental footprint.  Salmon that reach market size in 18 months instead of 30.

Genome 98
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Leading innovators in IgG gene expressing animal models for the pharmaceutical industry

Pharmaceutical Technology

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Regeneron has a market cap of $78.64

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CRISPR Therapeutics begins natural killer cell cancer tie-up with Nkarta

pharmaphorum

Founded by Nobel prize winner Emmanuelle Charpentier, CRISPR Therapeutics has been at the forefront of the gene editing technology and has refined it to the point where it can be used to accurately edit DNA to correct genetic conditions or modify cells to fight disease.

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How single-use technologies can improve antibodies production  

Drug Discovery World

RA: In recent years, what improvements have we seen to cell-line engineering for antibodies? DC: Antibodies have and remain a large product class within the biopharmaceutical market. AEX chromatography has primarily been used in the polishing AEX step for the removal of impurities, such as DNA, HCP, etc.,

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Accelerating recombinant protein vaccine discovery

Drug Discovery World

While a typical chemisty, manufacturing and controls (CMC) timeline from DNA to Investigational New Drug (IND) application in 2015 would have been approximately 24 months, by 2023 the same pathway was expected to take only 10 months. Consistent and reliable supply chains have also become a key consideration.

Protein 59
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Q&A with Mark Garner: The golden age of cancer research  

Drug Discovery World

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. As part of his graduate work he invented the gel-shift or EMSA assay for the study of protein-DNA interactions. Mark Garner, PhD.,