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Phases of Clinical Research: A Detailed Overview

Advarra

Clinical trials are studies involving human volunteers to research ways to prevent, detect, and treat various medical conditions. The goal is to identify safer, more effective methods of treating illnesses using new drugs or new combinations of existing drugs.

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Scepticism in press over Kintor’s COVID-19 US drug trial

pharmaphorum

China’s Kintor Pharmaceutical has begun late-stage US clinical development of its potential COVID drug proxalutamide – but there is scepticism over the company’s claims about its research. But Reuters reported that the doctor identified as its principal clinical trial investigator has said he is not in charge of the trial.

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Steps to building a more patient-centric industry

pharmaphorum

A recent survey of clinical trial professionals found that more than two-thirds of respondents (61%) believe giving patients choice will have a positive impact on clinical research, and well over half (58%) said that their organisations plan to give patients the option to choose how they participate in clinical trials moving forward.

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Personalising whole genome sequencing doubles diagnosis of rare diseases 

Drug Discovery World

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . It can also permit targeted screening of known disease complications and access to drug studies. Context .

Genome 52
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The medical school trying to become anti-racist

The Pharma Data

A major British medical school is leading the drive to eliminate what it calls “inherent racism” in the way doctors are trained in the UK. Exploring the fact that drug trials predominantly involve white, male participants, and looking at how this may lead to inaccurate and harmful prescribing for other patients.

Doctors 52
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Fatty liver disease: With little early detection, more challenging drug development

pharmaphorum

That was until my doctors stunned me with the news that I had cirrhosis caused by non-alcoholic steatohepatitis, or NASH, a severe form of fatty liver disease that often has few or no symptoms until very late stages. Cirrhosis is not just an “old drunk guys” disease, a stigma which has long hampered interest and investment in research.

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Why Black People Remain Underrepresented in Clinical Trials

XTalks

And Black people continue to face generational disenfranchisement in healthcare systems and medical research. The overwhelming majority of trial participants nationwide are white. There are multiple barriers that prevent active trial participation. They are also at a high risk of developing heart disease and stroke.