Pharmaceutical Technology

FEBRUARY 24, 2023

According to GlobalData, Phase III drugs for Type 2 Diabetes have a 53% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how (LAI-287 + semaglutide)’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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STAT News

MARCH 27, 2023

The Ohio attorney general filed a lawsuit on Monday accusing three large pharmacy benefit managers of fixing prices for various medicines, the latest effort to scrutinize the controversial companies that occupy a crucial role in pharmaceutical pricing.

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Fierce Pharma

MARCH 26, 2024

Demand for GLP-1 medicines from Eli Lilly and Novo Nordisk has exploded across the globe, resulting in on-and-off shortages in the U.S. Médecins Sans Frontières urged GLP-1 drug makers to "relinquish their stranglehold" on the products and license the meds to generics makers to boost access. and beyond.

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Pharmaceutical Technology

APRIL 10, 2023

India-based pharmaceutical company Cipla has entered into a perpetual licence agreement with Swiss drugmaker Novartis Pharma for the diabetes drug Galvus and its combination brands. Furthermore, Galvus can be used in combination with other medicinal products such as insulin when unable to offer adequate glycaemic control.

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pharmaphorum

MAY 16, 2022

Blood sugar control drug Mounjaro has been granted US regulatory approval, giving type 2 diabetics another way to help keep their glucose levels in check. GLP-1 and GIP are hormones involved in blood sugar control and Mounjaro, a first-in-class medicine that activates both GLP-1 and GIP receptors, demonstrated improved blood sugar control.

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Drug Discovery World

FEBRUARY 23, 2024

The top stories: Insulin independence without immunosuppression Preclinical data has demonstrated insulin independence following transplantation of hypoimmune (HIP) allogeneic primary islet cells without immunosuppression in a diabetic non-human primate (NHP).

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Drug Discovery World

JANUARY 31, 2024

In a world first, Sidra Medicine, a member of Qatar Foundation, has pioneered a new treatment protocol for a young infant with congenital hyperinsulinism. The findings were published in the New England Journal of Medicine. The medication regulates cell growth, proliferation and development and insulin signalling.

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Pharmaceutical Technology

APRIL 17, 2023

The US Food and Drug Administration (FDA) has approved an update to the indications and usage section of Horizon Therapeutics ’ Tepezza (teprotumumab-trbw) label to specify its use to treat thyroid eye disease (TED) patients regardless of disease activity or duration. The FDA’s approval was granted in January 2020.

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Pharmaceutical Technology

JUNE 29, 2022

The pharmaceutical industry often relies on enzymes to perform a process known as biocatalysis, which facilitates the cost-effective and sustainable production of small molecule drugs at scale. The next wave of medicine is well on course to be cell and gene-based. Developing best-in-class speciality enzymes.

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XTalks

FEBRUARY 24, 2021

The injection experience is an often-overlooked aspect in insulin administration. For many daily insulin users, the experience is an important one, as it is directly related to quality of life and medication compliance. Related: Droplet Micron Insulin Needle Offers Innovation in Crowded Diabetes Supply Market.

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The Pharma Data

FEBRUARY 25, 2021

and Eli Lilly and Company (NYSE: LLY) announced today a collaboration and licensing agreement to integrate Welldoc’s software into Lilly’s connected insulin solutions, currently in development. Lilly will commercialize the pen platform, which will include the new app and Lilly’s connected insulin pen solutions.

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Pharmaceutical Technology

MARCH 29, 2023

The partnership pursues an innovative approach to discovering and developing new medicines, using many of the modality-agnostic precision medicine platforms of Evotec. Together with our BMS colleagues, we are confident that we will deliver new medicines that matter to patients with neurodegenerative diseases.”

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Pharmaceutical Technology

JANUARY 31, 2023

The US omnibus bill passed in late December 2022 will give the agency greater powers to regulate accelerated approval drugs, while the Inflation Reduction Act’s lowering of drug prices will create an uncertain environment for drug developers, he said. That leaves three years for pharma companies to prepare.

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Drug Discovery World

JANUARY 15, 2024

Amgen and NVIDIA Amgen has announced plans to advance drug discovery using NVIDIA’s DGX SuperPOD-powered insights from human datasets. Chiesi and Oak Hill Bio Chiesi Group and Oak Hill Bio have entered a collaboration to develop OHB-607, a clinical-stage investigational drug candidate to treat complications of extremely premature birth.

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The Pharma Data

JUNE 28, 2021

In honor of the 100th anniversary of the discovery of insulin, Eli Lilly and Company (NYSE: LLY) today launched the Leonard Award to recognize diverse champions dedicated to advancing diabetes management through innovative thinking and novel approaches. Nominations are being accepted now until August 31, 2021 at Lilly.com/LeonardAward.

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STAT News

NOVEMBER 17, 2022

… UnitedHealth Group’s pharmacy benefits manager, OptumRx, will keep AbbVie’s Humira alongside up to three biosimilar medicines next year, Bloomberg News writes. in 2023, giving prescription drug plans a chance to pit different suppliers against one another for discounts. Optum Rx, which is the third-largest U.S.

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The Pharma Data

JULY 28, 2021

Novel small molecule drug candidates will target GPR75 to potentially address obesity and related co-morbidities. 1 Obesity and insulin resistance are key drivers in the development of type-2 diabetes and often lead to cardiorenal complications, as well as liver disease. Yancopoulos, M.D., Yancopoulos, M.D.,

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XTalks

JANUARY 5, 2024

Eli Lilly launched LillyDirect this week, an online service that provides access to the company’s medicines, including its newly approved weight loss drug Zepbound (tirzepatide). Interestingly, the company’s blockbuster diabetes drug, Mounjaro (tirzepatide), is not available through the new digital service.

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Delveinsight

AUGUST 18, 2021

In Type 2 diabetes, the body cells become resistant to insulin. The pancreas produces insulin that helps glucose get into cells to be used for energy. Due to Type 2 diabetes, either the body doesn’t make enough insulin or it doesn’t use insulin properly as a result the blood glucose or blood sugar gets too high.

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pharmaphorum

FEBRUARY 21, 2022

Bayer has claimed EU approval for Kerendia, its new drug for chronic kidney disease (CKD) in people with type 2 diabetes, as the company tries to build a role of the drug alongside rival therapies from AstraZeneca and Johnson & Johnson. The post EU clears Bayer’s chronic kidney disease drug Kerendia appeared first on.

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Pharmaceutical Technology

MAY 17, 2023

The Inflation Reduction Act, which became US law in August 2022, has invited its fair share of critics and supporters over its drug pricing provisions. At the core of the debate was a new provision allowing the US Centers for Medicare & Medicaid Services (CMS) to negotiate prices with pharmaceutical companies for a select number of drugs.

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Scienmag

SEPTEMBER 29, 2020

Sitagliptin blocks coronavirus from entering cells, reduces inflammation; observational findings have sparked a placebo-controlled trial BOSTON – Sitagliptin, a drug to lower blood sugar in type 2 diabetes, also improves survival in diabetic patients hospitalized with COVID-19, suggests a multicenter observational study in Italy.

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pharmaphorum

FEBRUARY 3, 2022

As Part of Europe’s leading Injectable conference series, we will assess innovations in drug product formulation and biologics, new technologies in device design and the use of long-release injectable compounds. There is a rising demand for vaccines, insulin, and many modern medicines used to treat cancer and other chronic diseases.

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Drug Discovery World

OCTOBER 11, 2022

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new class of treatment for adults with insufficiently controlled type 2 diabetes. . Tirzepatide is approved as monotherapy when metformin is inappropriate due to intolerance or contraindications or in addition to other medicinal products.

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Pharmaceutical Technology

DECEMBER 22, 2022

The main focus is the antibody-drug conjugate (ADC ), Enhertu (trastuzumab deruxtecan), which had already achieved regulatory approval as a second-line therapy for metastatic or recurrent HER2-positive breast cancer, as well as HER2-positive gastric or gastroesophageal junction adenocarcinoma. Innovation.

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Drug Discovery World

NOVEMBER 14, 2022

Alternative to insulin. Early-stage biopharma company Atrogi initiated a Phase I study for its drug candidate ATR-258 targeting type 2 diabetes in Germany, which is expected to announce results at the end of the year. . Find out more: New human beta cell model enables discoveries in diabetes research .

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XTalks

JANUARY 25, 2023

Massachusetts-based TheracosBio has received US Food and Drug Administration (FDA) approval for diabetes med Brenzavvy (bexagliflozin) to help improve glycemic control in adults with type 2 diabetes. The drug is taken once a day in conjunction with diet and exercise. What is the Animal Drug Regulatory Process?

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The Pharma Data

DECEMBER 17, 2020

7, 2020 — After starting a drug that’s officially approved to treat a type of blood cancer, a young man with type 1 diabetes was able to stop using insulin. He’s been off insulin since August 2018 — more than two years. Whether this drug can help others with type 1 diabetes isn’t yet known.

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Pharmacy Checkers

JULY 2, 2019

One of the Sustainable Development Goals, 3.8 , created under UN auspices is: “Achieve universal health coverage, including financial risk protection, access to quality essential health-care services and access to safe, effective, quality and affordable essential medicines and vaccines for all.” as it applies to access to affordable medicine.

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Scienmag

FEBRUARY 10, 2021

Animal venoms as natural resource for new drugs “Insulin is a prime example for a successful peptide drug that has been essential for the health of millions of diabetic patients in the past 100 years,” says Markus Muttenthaler, who leads research groups at the Institute of Biological Chemistry of the Faculty of Chemistry at University […]. (..)

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Roots Analysis

JANUARY 23, 2024

The peptide therapeutics market has undergone substantial evolution since the inception of insulin. Presently, over 80 peptide-based drugs are available in the market for myriad of disorders and diseases. Presently, over 80 peptide-based drugs are available in the market for myriad of disorders and diseases.

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pharmaphorum

JUNE 2, 2022

R&D into orphan drugs is growing alongside the number of approved treatments, providing treatments for rare diseases that previously did not have any. Evaluate Pharma’s recent Orphan Drug Report subtitled its overview of the market ‘Niche no longer.’ It is estimated that between 3.5

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STAT News

DECEMBER 5, 2022

… Johnson & Johnson said it does not intend to make an offer for Horizon Therapeutics, days after the developer of medicines for rare autoimmune and inflammatory diseases revealed it was in talks with the company , Bloomberg News writes. We hope you have a smashing day and, of course, encourage you to keep in touch.

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World of DTC Marketing

JUNE 6, 2022

When the body is swamped with sugar, it can become resistant to insulin. Combining different checkpoint inhibitor drugs or administering them alongside CAR-T and other therapies has yielded incremental advances. Of the 332 approvals over those 12 years, only 16% were based on new drug approaches. ASCO focuses on CAR-T.

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Drug Discovery World

JULY 29, 2022

Type 1 diabetes is a potentially life-threatening chronic condition in which the pancreas produces little or no insulin. We found boosting the regulatory T-cells using sRAGE in the pancreas, pancreatic lymph nodes and spleen prevented diabetes, and also resulted in better insulin expression and function,” Dr Leung said.

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The Pharma Data

FEBRUARY 1, 2021

1, 2021 — Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds. Exactly how this drug may protect women with diabetes from breast cancer is less clear. MONDAY, Feb.

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Rethinking Clinical Trials

AUGUST 22, 2022

Assistant Professor, General Internal Medicine and Pediatrics. Core Faculty, Center for Pediatric Obesity Medicine. The dosing for the drugs during the trial was Ivermectin 390 (470mcg/kg/day x 3 days), Metformin titration to 1,500mg/day over 7 days, and Fluvoxamine 50mg. Carolyn Bramante, MD, MPH. Thomas Murray, PhD.

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