Thu.Apr 04, 2024

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Trial finds benefit for GLP-1 agonist in Parkinson’s

pharmaphorum

A small study of Sanofi’s lixisenatide has suggested that the GLP-1 agonist could slow down the progression of Parkinson’s disease, pointing to another potential use for the fast-growing drug class.

Trials 100
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Merck puts KRAS cancer drug competitor to the test

Bio Pharma Dive

A Phase 3 study will compare Merck’s experimental KRAS inhibitor together with its immunotherapy Keytruda against Keytruda alone in lung cancer.

Drugs 265
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Hand Sanitizers Could Damage Critical Supporting Cells In The Brain

AuroBlog - Aurous Healthcare Clinical Trials blog

Chemicals found in common household disinfectants, glues, and furniture textiles could damage supporting cells in the brain during critical stages of their development, a new study based on human cell cultures and mice has found.

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April 4, 2024: ICD-Pieces Trial Sees No Reduction in Hospitalization for Patients With Chronic Kidney Disease

Rethinking Clinical Trials

Dr. Miguel Vazquez, principal investigator for ICD-Pieces A primary care intervention for patients with coexisting chronic kidney disease, type 2 diabetes, and hypertension did not reduce the hospitalization rate for these patients when compared to usual care, according to the ICD-Pieces study. The results of the study were published this week in the New England Journal of Medicine.

Trials 161
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Amylyx to pull ALS drug from market in rare move

Bio Pharma Dive

In the wake of a major trial failure, the company is withdrawing Relyvrio and cutting costs with a restructuring that involves laying off 70% of its employees.

Marketing 171
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F. Hoffmann-La Roche gets grant for system for identifying nucleic acid bases using nanopore technology

Pharmaceutical Technology

Discover how F. Hoffmann-La Roche's patented system uses nanopores to identify nucleic acid bases, increasing confidence in base identification. Explore the innovative approach in genomics and personalized medicine.

Genome 147

More Trending

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Contineum prices biotech’s latest IPO, raising $110M for neuroinflammatory drugs

Bio Pharma Dive

The offering keeps new biotech stock offerings on their strongest pace in three years, accompanying an uptick in private company funding.

Drugs 164
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Chiesi Farmaceutici gets grant for pharmaceutical formulation for intraduodenal administration with melevodopa and carbidopa

Pharmaceutical Technology

Discover Chiesi Farmaceutici's innovative patent for a specialized pharmaceutical formulation aimed at enhancing drug delivery efficiency for Parkinson's disease treatment. Learn about the unique composition and processes involved in this groundbreaking intraduodenal administration solution.

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FDA approves new antibiotic for several hard-to-treat infections

Bio Pharma Dive

Swiss pharma Basilea has won clearance for Zevtera after a long development journey, but is still searching for a commercial partner in the U.S.

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Xencor gets grant for bispecific antibody for treating GPC3-associated cancers

Pharmaceutical Technology

Discover Xencor Inc's groundbreaking patent for novel GPC3 binding domains and bispecific antibodies targeting GPC3-associated cancers. Explore the innovative method for manufacturing these antibodies and their potential in cancer treatment.

Antibody 130
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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A Guide to Gastric Sleeve Surgery or Sleeve Gastrectomy

Pharma Mirror

Gastric sleeve surgery, also known as sleeve gastrectomy, is a surgical procedure designed to aid in weight loss for individuals struggling with obesity. During the procedure, a significant portion of the stomach is removed, leaving a smaller, sleeve-shaped stomach roughly the size of a banana. This reduction in stomach size restricts the amount of food a person can consume, leading to decreased calorie intake and, consequently, weight loss.

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Lipocine gets grant for pharmaceutical composition for treating testosterone deficiency

Pharmaceutical Technology

Discover Lipocine Inc's innovative patent for bioavailable solid state esters to treat testosterone deficiency in mammals. Learn about the unique pharmaceutical composition and release characteristics for optimal delivery and efficacy.

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How long do clinical trials take?

Antidote

Before it is released onto the market, the development of any new drug or medical device must undergo rigorous testing , part of which involves clinical trials. Clinical trials are integral to making sure that any new therapy is both safe and effective for individuals, and volunteers are a vital part of the process.

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United Therapeutics gets grant for treatment of pulmonary hypertension using prostacyclin-treated stem cells

Pharmaceutical Technology

Discover a groundbreaking method for treating pulmonary hypertension with stem cells and prostacyclin. Learn more about this innovative patent from United Therapeutics Corp.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Amylyx to pull failed ALS drug Relyvrio from market, cut 70% of staffers

Fierce Pharma

Amylyx Pharmaceuticals is keeping a promise by pulling the amyotrophic lateral sclerosis (ALS) therapy Relyvrio off the market after the drug failed in a confirmatory trial. | Amylyx is keeping a promise by pulling the amyotrophic lateral sclerosis (ALS) therapy Relyvrio off the market after the drug failed in a confirmatory trial. And 70% of the company's staff will soon lose their jobs.

Marketing 107
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HCA Healthcare gets grant for wrist brace with advantageous lacing configuration for compression

Pharmaceutical Technology

Discover the innovative wrist brace by HCA Healthcare Inc, featuring a unique lacing system for consistent compression and effective support. Patent details included!

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Keurig’s New K-Rounds + How To Good To Go Saves Millions of Meals – Xtalks Food Podcast Ep. 153

XTalks

Keurig has taken a bold step forward with the unveiling of its first-ever 100 percent compostable coffee pods, dubbed “K-Rounds.” This innovation not only marks a significant milestone in the company’s journey toward sustainability but also addresses the longstanding issue of plastic waste from traditional coffee pods. In this episode of the Xtalks Food Podcast, Sydney talks about the new sustainable offering, which was designed exclusively for Keurig’s new Alta machine.

Branding 105
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Incyte gets grant for treatment of various cancers using specific compound

Pharmaceutical Technology

Discover how Incyte Corp's patent targets adenosine receptors to treat cancer, inflammation, and more. Learn about the specific compound for cancer treatment.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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How MALK Organics Is Leading the Plant-Based Milk Revolution

XTalks

MALK Organics is reshaping the plant-based milk industry with its commitment to purity and simplicity. Founded in 2015, MALK Organics has become synonymous with quality and innovation in alternative milk products. Let’s explore MALK Organics’ history, its competitors and what sets it apart in a fiercely competitive market. The Evolution of MALK Organics MALK Organics was spearheaded by a vision to offer cleaner, more wholesome plant-based milk alternatives.

Branding 104
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Clinical trials and development services

Pharmaceutical Technology

Download our comprehensive list of leading specialist companies offering clinical trials and development services for free today.

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Teva’s AUSTEDO XR Campaign Featured in MM+M

Intouch Solutions

MM+M recently named Teva Pharmaceuticals’ AUSTEDO XR campaign as their Campaign of the Week! AUSTEDO XR helps treat tardive dyskinesia (TD), a side effect of taking medications for mental illness. It’s estimated that some 85% of TD cases go undiagnosed. To help patients and HCPs recognize TD, our team partnered with Teva on two new TV spots focusing on two different journeys of characters who have TD.

Branding 104
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Addex spinoff Neurosterix debuts with $63m for developing neurological therapies

Pharmaceutical Technology

Addex has also sold its preclinical neurological assets and drug discovery platform to Neurosterix for $5.5m and 20% equity.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Vox Pop Pharma – the industry speaks out about advanced AI and biophysical modeling

Outsourcing Pharma

In an overwhelming response to the news that SimBioSys and General Inception had joined forces to use advanced AI and biophysical modeling, to gain deeper insights into tumor biology, the industry has spoken.

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Touchlight joins forces with University of Liverpool for NSCLC vaccine

Pharmaceutical Technology

The vaccines will be developed using Touchlight’s doggybone DNA technology, which speeds up the manufacturing process.

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AI-powered real-world evidence generation for biotechs

pharmaphorum

Discover how AI-powered real-world evidence generation is revolutionising the biotech industry, providing valuable insights for biopharma companies to make informed decisions. Learn more about the impact of RWD on biotechs.

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Microbiome drug to be tested in IBS clinical trial

Drug Discovery World

EnteroBiotix, a Glasgow, UK based biotechnology company, has dosed the first patient in a clinical trial designed to evaluate EBX-102-02 for the treatment of irritable bowel syndrome (IBS). The Phase II study, named ‘TrIuMPH’ (treating IBS with an intestinal microbiota product for health) will initially enrol 60 patients with IBS and constipation across sites in the UK.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Bringing CAR-T into the community: ‘Healthcare is like politics – it’s local’

BioPharma Reporter

Today, just two in ten patients have access to CAR-T therapy in the US. Considering this challenging landscape, the shift has focused from academic centers to community clinics, as they may be able to serve more patients.

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Life is still buzzing at Trialbee - CEO Matt Walz on successfully guiding patients through clinical trials

Outsourcing Pharma

In February, Trialbee announced its Omnichannel Network partnership with Massive Bio, a global leader in AI-enabled patient journey mapping platform to help better connect cancer patients with their oncologists/hematologists in clinical trials.

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Praia emerges with $20m for digital health platform

pharmaphorum

Healthcare system Providence has spun out a new company, Praia Health, focused on a platform to build and sustain connections between patients and health providers. The new company starts life with $20 million in Series A funding and a mission to develop the Praia Health Identity and Engagement Platform, which was launched within Providence’s digital innovation group (DIG) incubator in 2022 and already handles around 3.5 million user accounts.

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Study reveals new aptamer targeting tool can detect early signs of motor neurone disease

Pharma Times

The fatal, progressive neurological condition currently affects around 5,000 people in the UK

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.