BioSpace
MAY 23, 2021
The Francis Crick Institute and the Latvian Institute of Organic Synthesis developed a new compound that blocks the life cycle of the mosquito-borne parasite that causes malaria.
Scienmag
MAY 23, 2021
These Oncotarget findings suggest that urine IL-1?, IL-1ra and IL-8 are useful indicators of bladder cancer. Credit: Correspondence to – Chandra Mohan – cmohan@central.uh.edu Oncotarget published “Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens” which reported that the current study examines urine samples from 66 subjects, comprising of 31 Urology clinic controls […].
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BioSpace
MAY 23, 2021
The disclosure comes the day before the WHO is expected to plan for the next phase of investigations into the origins of COVID-19.
JAMA Internal Medicine
MAY 23, 2021
This follow-up study of the CORIMUNO-TOCI-1 randomized clinical trial examines the association between survival and C-reactive protein levels in patients hospitalized with COVID-19 who were treated with tocilizumab.
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Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud
BioSpace
MAY 23, 2021
Pfizer, Sagent Pharmaceuticals and Merck are preparing their antiviral pills against SARS-CoV-2 and are showing promise in new clinical trials.
Scienmag
MAY 23, 2021
Research teams across the UK will investigate the viability of five innovative methods of large-scale greenhouse gas removal to counter the impact of climate change Credit: UKRI Research teams across the UK will investigate the viability of five innovative methods of large-scale greenhouse gas removal from the atmosphere to help the UK reach its legislated […].
Clinical Research Informer brings together the best content for clinical researchers from the widest variety of industry thought leaders.
Drug Patent Watch
MAY 23, 2021
ZOMIG (zolmitriptan) Astrazeneca Patent: 7,220,767 Expiration: May 28, 2021 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit…. The post Drug Patent Expirations for the Week of May 23, 2021 appeared first on DrugPatentWatch - Make Better Decisions.
BioSpace
MAY 23, 2021
It’s a busy week for the U.S. Food and Drug Administration, with a number of drug approvals on the calendar and an advisory committee meeting. Read on for more information.
Scienmag
MAY 23, 2021
The gene correlates of LP-184 sensitivity allow additional personalization of therapeutic options for future treatment of NSCLC Credit: Correspondence to – Aditya Kulkarni – aditya@lanternpharma.com Oncotarget published “The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations” which reported that KEAP1 mutant NSCLCs further activate NRF2 and upregulate […].
BioSpace
MAY 23, 2021
Takeda has touted the potential of its Dengue vaccine for several years, and new long-term data reinforces the promise of the medication that could prevent the deadly mosquito-borne virus.
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White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations
Scienmag
MAY 23, 2021
Credit: Courtesy of Nicole Malofsky and Mari-Therese Burton / Lehigh University Rossin College PhD students Mari-Therese Burton (materials science and engineering) and Nicole Malofsky (bioengineering) have been selected for prestigious national STEM research fellowships. Malofsky, who is advised by Lesley Chow, an assistant professor of bioengineering and materials science and engineering, will receive support through […].
BioSpace
MAY 23, 2021
NGM Bio's aldafermin failed to hit its primary endpoint in its Phase IIB trial because of that, the company decides to shift resources to other programs.
Scienmag
MAY 23, 2021
Dr. Munir R. Tanas from The University of Iowa said, ‘Sarcomas are difficult to treat malignant mesenchymal neoplasms arising in bone or soft tissue’ Credit: Correspondence to – Munir R. Tanas – munir-tanas@uiowa.edu Oncotarget published “Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas” which reported that herein the authors […].
BioSpace
MAY 23, 2021
Wang, who has played a key role in the development of more than 25 innovative medicines at Eli Lilly and GlaxoSmithKline, made him the ideal fit for the company’s next chapter.
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When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.
Scienmag
MAY 23, 2021
Abnormal blood-oxygen levels and breathing rates are strong predictors of poor patient outcomes in-hospital, study shows A study of 1,095 patients hospitalized with COVID-19 discovered that two easily measurable signs of health – respiration rate and blood-oxygen saturation – are distinctly predictive of higher mortality. Notably, the authors said, anyone who receives a positive COVID-19 […].
BioSpace
MAY 23, 2021
It was another busy week for clinical trial announcement. Here’s a look.
Scienmag
MAY 23, 2021
Press release – Abstract 1394: Alterations in clock genes expression in Eutopic and Ectopic Endometrial Tissue New research suggests that night shift work is linked to menstrual irregularity and increased chance of developing endometriosis According to a study being presented at the 23rd European Congress of Endocrinology (e-ECE 2021), on Sunday 23 May at 19:00 […].
NY Times
MAY 23, 2021
Experts say more scientific research is needed. Also: Aid to Afghanistan after the withdrawal.
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This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.
Scienmag
MAY 23, 2021
Regular consumption of milk is not associated with increased levels of cholesterol, according to new research. A study published in the International Journal of Obesity looked at three large population studies and found that people who regularly drank high amounts of milk had lower levels of both good and bad cholesterol, although their BMI levels […].
BioTech 365
MAY 23, 2021
Addex to Participate at the Benchmark Company Healthcare House Call Conference Addex to Participate at the Benchmark Company Healthcare House Call Conference Geneva, Switzerland, May 24, 2021 – Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage pharmaceutical company pioneering … Continue reading →
Scienmag
MAY 23, 2021
Epigenetic changes associated with greater inflammation and fatigue New research indicates that certain anti-cancer therapies may hasten cellular aging, where changes in the DNA of patients may contribute to greater inflammation and fatigue. The findings are published by Wiley early online in CANCER, a peer-reviewed journal of the American Cancer Society.
BioTech 365
MAY 23, 2021
NGM Bio to Host Conference Call to Discuss Topline Results from 24-Week Phase 2b ALPINE 2/3 Study of Aldafermin in NASH NGM Bio to Host Conference Call to Discuss Topline Results from 24-Week Phase 2b ALPINE 2/3 Study of Aldafermin … Continue reading →
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As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.
Drug Patent Watch
MAY 23, 2021
This chart shows the drugs with the most patents in Singapore. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.…. The post Which pharmaceutical drugs have the most drug patents in Singapore? appeared first on DrugPatentWatch - Make Better Decisions.
BioTech 365
MAY 23, 2021
Bristol Myers Squibb Presents New Data at Digestive Disease Week® on Zeposia (ozanimod) Highlighting Clinical Benefits and Safety Profile in Patients with Ulcerative Colitis Bristol Myers Squibb Presents New Data at Digestive Disease Week® on Zeposia (ozanimod) Highlighting Clinical Benefits … Continue reading →
BioTech 365
MAY 23, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: China’s Yuan Longping dies; rice research helped feed world.
BioTech 365
MAY 23, 2021
InspirMed Highlights Encouraging Data on ISPM21 and ISPM19 – Inhalable Liposome Formulations of Antiviral Drugs for COVID-19 InspirMed Highlights Encouraging Data on ISPM21 and ISPM19 – Inhalable Liposome Formulations of Antiviral Drugs for COVID-19 SOUTH SAN FRANCISCO, Calif.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioTech 365
MAY 23, 2021
EQS Group-News: Rapid Nutrition PLC / Key word(s): Miscellaneous 24.05.
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