Fri.Oct 23, 2020

FDA clears AstraZeneca to restart large coronavirus vaccine study

Bio Pharma Dive

The drugmaker's U.S. trial has been on pause since early September after an unexplained illness in one participant triggered safety reviews worldwide

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Cause of Alzheimer’s disease traced to mutation in common enzyme

Scienmag

Mutation to MARK4 makes proteins stickier and more likely to clump in brain Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University have discovered a new mechanism by which clumps of tau protein are created in the brain, killing brain cells and causing Alzheimer’s disease.

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At key meeting, FDA advisors debate if early coronavirus vaccine approvals may compromise trials

Bio Pharma Dive

An emergency clearance is expected for the first vaccine proven effective. But early availability of a shot could jeopardize ongoing studies, and may make tests of other candidates more difficult

Novartis launches digital health hub in Canada

Pharma Phorum

Novartis is opening a new digital health innovation hub in Canada to help develop “scalable, digital solutions” for patients and healthcare providers. The Canadian Biome Digital Innovation Hub will be based in Montreal at the artificial intelligence research institute, Mila.

Ultragenyx expands into Duchenne gene therapy with Solid Bio deal

Bio Pharma Dive

The rare disease drug developer is betting it can create a better DMD treatment by combining Solid's research with its manufacturing and gene delivery technology

Fipronil, a common insecticide, disrupts aquatic communities in the U.S.

Scienmag

Credit: Photo courtesy of Janet Miller The presence of insecticides in streams is increasingly a global concern, yet information on safe concentrations for aquatic ecosystems is sometimes sparse.

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New imaging method reveals HIV’s sugary shield in unprecedented detail

Scienmag

The technique should help in the design of vaccines against HIV, SARS-CoV-2 and other viruses that cloak their outer proteins with sugars to evade antibodies.

Data hackathon analyses truth behind TB vaccine and COVID-19

Pharma Phorum

Is a century-old vaccine a ‘game-changer’ for COVID-19? Anita de Waard from Elsevier and Radoslav Kirkov from Estafet tells us how a hackathon is harnessing data science to look beyond the hype and seek definitive clinical evidence.

Coastal permafrost more susceptible to climate change than previously thought

Scienmag

Credit: Bayani Cardenas If you flew from the sea towards the land in the north slope of Alaska, you would cross from the water, over a narrow beach, and then to the tundra. From the air, that tundra would look like a landscape of room-sized polygonal shapes.

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New patent for Therapeuticsmd Inc drug IMVEXXY

Drug Patent Watch

Annual Drug Patent Expirations for IMVEXXY Imvexxy is a drug marketed by Therapeuticsmd Inc and is included in one NDA. It is available from one supplier. There are eight patents…. The post New patent for Therapeuticsmd Inc drug IMVEXXY appeared first on DrugPatentWatch - Make Better Decisions.

Mary Ann Liebert, Inc. to publish Journal of Correctional Health Care

Scienmag

Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, October 23, 2020–The National Commission on Correctional Health Care (NCCHC) ([link] has awarded the contract to publish Journal of Correctional Health Care ([link] to Mary Ann Liebert, Inc.,

New patent for Celgene drug POMALYST

Drug Patent Watch

Annual Drug Patent Expirations for POMALYST Pomalyst is a drug marketed by Celgene and is included in one NDA. It is available from one supplier. There are eleven patents protecting…. The post New patent for Celgene drug POMALYST appeared first on DrugPatentWatch - Make Better Decisions.

RUDN University chemist created a catalyst from orange peel for organic compounds production

Scienmag

Credit: RUDN University N-heterocycles are organic substances used in the chemical industry and medicine. To produce them, expensive catalysts made from noble metals are used.

New patent for Vertex Pharms drug KALYDECO

Drug Patent Watch

Annual Drug Patent Expirations for KALYDECO Kalydeco is a drug marketed by Vertex Pharms Inc and Vertex Pharms and is included in two NDAs. It is available from one supplier.…. The post New patent for Vertex Pharms drug KALYDECO appeared first on DrugPatentWatch - Make Better Decisions. Patent Adde

Elkhorn coral actively fighting off diseases on reef, study finds

Scienmag

Findings showed coral has core immune response regardless of disease type Credit: Photo: Margaret Miller, SECORE International MIAMI–As the world enters a next wave of the ongoing COVID-19 pandemic, we are aware now more than ever of the importance of a healthy immune system to protect ourselves from disease.

Kezar Life Sciences Announces Orphan Drug Designations for KZR-616 for the Treatment of Polymyositis and Dermatomyositis

BioTech 365

SAN FRANCISCO–(BUSINESS WIRE)–Kezar Life Sciences, Inc. Nasdaq: KZR), a clinical-stage biotechnology company discovering and developing breakthrough treatments for immune-mediated and oncologic disorders, today announced that the U.S.

Exploring the source of stars and planets in a laboratory

Scienmag

Credit: Collage by Elle Starkman/PPPL Office of Communications. A new method for verifying a widely held but unproven theoretical explanation of the formation of stars and planets has been proposed by researchers at the U.S.

A Creative Origin Story in a Newspaper Clipping

Intouch Solutions

What's your career origin story? In this post, we look at Intouch SVP, Executive Creative Director Brent Scholz's very first advertisement and how it inspired his lifelong passion. The post A Creative Origin Story in a Newspaper Clipping appeared first on Intouch Solutions. Intouch Culture Creative

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Cyanobacteria: Small candidates as great hopes for medicine and biotechnology

Scienmag

Merck KGaA, IAVI and Serum Institute link up to develop COVID-19 mAbs

Pharma Times

Agreement will see partners develop SARS-CoV-2 neutralising monoclonal antibodies

Oncotarget: A novel format for recombinant antibody-interleukin-2 fusion proteins

Scienmag

Oncotarget recently published a novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo which reported that here, the authors describe four novel formats for the L19-IL2 fusion Credit: Correspondence to – Dario Neri – dario.neri@pharma.ethz.ch

American College of Surgeons, Oct. 3-7

The Pharma Data

The 105th Annual American College of Surgeons Clinical Congress. The annual meeting of the American College of Surgeons was held virtually this year from Oct. 3 to 7 and attracted participants from around the world, including surgeons, medical experts, allied health professionals, and administrators.

Engineering drought-resistant crops with Crassulacean acid metabolism (CAM) photosynthesis

Scienmag

Researchers study of the effects of introducing water-saving CAM photosynthesis, which is used by plants that are able thrive in arid conditions, into C3 plants grown in temperate climates.

Global dPCR Market- Featuring Avance Biosciences Inc., Becton, Dickinson and Co., and Bio-Rad Laboratories Inc. Among Others

BioTech 365

LONDON–(BUSINESS WIRE)–#GlobaldPCRMarket–The dPCR market is poised to grow by USD 518.69 million during 2020-2024, progressing at a CAGR of over 24% during the forecast period.

Timekeeping theory combines quantum clocks and Einstein’s relativity

Scienmag

Research reveals new time dilation phenomenon Credit: Petra Korlevic HANOVER, N.H.

Liquid Biopsy Market | COVID-19 Recovery and Growth Opportunities | Technavio

BioTech 365

LONDON–(BUSINESS WIRE)–#GlobalLiquidBiopsyMarket–The liquid biopsy market is poised to grow by USD 4.02 billion during 2020-2024, progressing at a CAGR of almost 38% during the forecast period.

The Lancet Infectious Diseases: Study provides estimates of the effect of introducing and lifting physical distancing measures on COVID-19 reproduction (R) number

Scienmag

Modelling analysis of measures in 131 countries confirms that combined measures are likely to reduce the R more than individual measures Modelling analysis of measures in 131 countries confirms that combined measures are likely to reduce the R more than individual measures. Authors looked at four possible combinations of measures, with the least comprehensive package […].

‘Tough Guy’ Mentality Keeps Athletes in Denial About Pain

The Pharma Data

FRIDAY, Oct. 23, 2020 — A culture of toughness and resilience is encouraged among elite college rowers, but it can keep them from reporting injuries, a new study finds. There’s an overall myth among athletes that admitting pain is a sign of weakness and failure, the researchers said.

FDA Approves FoundationOne®CDx as Companion Diagnostic for Vitrakvi® (larotrectinib), to Aid in Identifying NTRK Fusion-Positive Patients

BioTech 365

Nearly 130,000 U.S. Lives Saved by March if Everyone Wore Masks: Study

The Pharma Data

FRIDAY, Oct. 23, 2020 — A resurgence of the new coronavirus is bearing down upon the United States, with hundreds of thousands more deaths likely to occur over the next few months, according to one of the nation’s top epidemic modeling teams.

FoundationOne®CDx Receives FDA-Approval as a Companion Diagnostic for VITRAKVI®(larotrectinib) to Identify Patients with NTRK Fusions Across All Solid Tumors

BioTech 365

CAMBRIDGE, Mass.–(BUSINESS –(BUSINESS WIRE)–Foundation Medicine, Inc. today announced that it has received approval from the U.S.

American Society of Anesthesiologists, Oct. 2-5

The Pharma Data

ANESTHESIOLOGY 2020. The annual meeting of the American Society of Anesthesiologists was held virtually this year from Oct. 2 to 5 and attracted participants from around the world, including anesthesiologists and other health care professionals.

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PMI Announces Medicago to Supply Up to 76 Million Doses of Its Plant-Derived COVID-19 Vaccine Candidate

BioTech 365

A Philip Morris International subsidiary is a shareholder in a biopharmaceutical company that reached agreements with two departments of the Canadian government to accelerate its COVID-19 vaccine candidate efforts LAUSANNE, Switzerland–(BUSINESS WIRE)–Since 2008, Philip Morris Investments B.V.

APA: Americans Are Stressed, Particularly Young Adults

The Pharma Data

Professional. APA: Americans Are Stressed, Particularly Young Adults. FRIDAY, Oct.

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