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Gene expression delivery tool ‘slides’ instructions into cells

Drug Discovery World

Splicing-linked expression design. Two methods currently used to deliver protein-making packages into cells, ‘mini promoters’ and serotype-mediated gene expression, vary widely. Two methods currently used to deliver protein-making packages into cells, ‘mini promoters’ and serotype-mediated gene expression, vary widely.

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Moving the needle of CAR-T beyond oncology 

Drug Discovery World

CAR-T Therapies have revolutionised the field of personalised medicine, especially in oncology. Orchestrating the naturally occurring conductors of gene expression can shift the functional state of cells and alter gene expression. These factors can be harnessed to improve CAR T-cell engineering.

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Gene editing: beyond the hype

pharmaphorum

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. Then over the next two or three years, gene therapy was accepted as something that companies got involved in, and several biotechs have been bought up by big pharma.”.

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Combining the Powers of Single Cell Sequencing and AI in Understanding Disease Biology and Drug Development

XTalks

The detailed complexity of these processes can be captured by creating models that combine correlates of gene and protein expression, providing insight into the molecular composition of tissues. Visium Spatial Gene Expression Solution. Feature barcoding using gel beads. Leading Innovations in Single Cell Technology.

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The Dose: DDW’s drug discovery highlights

Drug Discovery World

The announcement followed the signing of deals to make new medicines available across the country. . Dr Ramakrishnan, who holds a Bachelor of Biotechnology and Biochemical Engineering from the University of Kerala in India, presented a proposal examining microbiome-based therapeutics for asthma. .

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Delivering on the promise of gene editing

Drug Discovery World

Inducing double strand breaks at unintended locations in the genome can lead to off-target genetic modifications that are difficult to predict and potentially deleterious. Complicating matters even more, researchers currently lack effective and reliable methods for detecting and measuring off-target genomic events.

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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Synthetic libraries for antibody drug discovery .

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