The Pharma Data

MARCH 7, 2022

Because these modifications occur not in, but on top of genes, they are called epigenetic, from the Greek epi “over” or “above” the genes. The chemical modifications that regulate gene activity are called epigenetic markers. Cas9 is the protein used in the gene editing process called CRISPR.

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Protein Gene Genome Genomics 52

Drug Discovery World

JANUARY 23, 2023

Kevin Hemphill, R&D Manager at PerkinElmer’s Horizon Discovery explores how base editing has emerged as an attractive gene editing option for researchers wanting to develop stem cell-based therapies. Adult fibroblasts were cultured in a cocktail of transcription factors to reactivate embryonic gene expression patterns 2.

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Gene Editing Gene Engineer DNA 52

Drug Discovery World

JULY 18, 2023

CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg. In the context of non- infectious diseases, CRISPR diagnostics have been developed to detect RNA species, such as human CXCL9 mRNA, for kidney transplant rejection. parvovirus B19, Flaviviridae, Ebola, and Coronaviridae), DNA viruses (e.g.,

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DNA Genome Genomics RNA 98

XTalks

MAY 4, 2021

These modifications regulate gene expression without changing the sequence or structure of DNA. The CRISPR gene editing system consists of the Cas9 enzyme, which serves as molecular scissors to cleave double-stranded DNA, and a guide RNA template targeted to a specific genomic sequence, which allows for precise editing.

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DNA Gene Gene Silencing Genome 98

XTalks

MAY 4, 2021

These modifications regulate gene expression without altering the sequence or structure of DNA. The CRISPR gene editing system consists of the Cas9 enzyme, which serves as molecular scissors to cleave double-stranded DNA, and a guide RNA template targeted to a specific genomic sequence, which allows for precise editing.

DNA 52

DNA Gene Gene Silencing Genome 52

XTalks

SEPTEMBER 21, 2020

UCSF scientists found that having an additional copy of the sex chromosome gives women two “doses” of a gene found only on that chromosome. To further confirm these results, the scientists deleted the second X in female Alzheimer’s mice, which led them to be more cognitively impaired like males and die faster. The Active Gene.

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Gene Protein Gene Expression Scientist 89

XTalks

DECEMBER 24, 2020

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.

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