Scienmag

NOVEMBER 25, 2021

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated. Published in the journal Science, the findings reveal a novel mechanism that coordinates the assembly of components inside cells that control gene expression.

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Scienmag

MARCH 9, 2021

CHOP researchers find small changes in RNA due to RNA editing could have a large impact on gene expression and phenotype Philadelphia, March 9, 2021–Combining computational mining of big data with experimental testing in the lab, researchers at Children’s Hospital of Philadelphia (CHOP) have identified RNA editing events that influence (..)

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Scienmag

MARCH 11, 2021

Study marks the first time this complex has been visualized for human cells Credit: Northwestern University For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression.

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Bio Pharma Dive

NOVEMBER 17, 2021

Chroma Medicine's launch is the latest step in a decadeslong quest by drugmakers to capitalize on research into epigenetics, a way of controlling gene expression without altering DNA.

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Scienmag

OCTOBER 1, 2020

The type and direction of the force on a cell alters gene expression by stretching different regions of DNA, researchers at University of […]. . — Tissues and cells in the human body are subjected to a constant push and pull – strained by other cells, blood pressure and fluid flow, to name a few.

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AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 15, 2022

The authors of the study say their research is the first to link COVID-19 to molecular signatures of brain aging. “We observed that gene expression in the brain tissue of patients who died […].

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BioTech 365

DECEMBER 1, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers identify key RNA “gatekeeper” in gene expression, pointing to possible new drug targets.An

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BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without changing DNA.MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without … Continue reading → (..)

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BioTech 365

JULY 28, 2021

BostonGene Announces Publication in Clinical Cancer Research Identifying the Cellular Features and Gene Expression Characteristics Underlying MRI Visibility in Prostate Cancer BostonGene Announces Publication in Clinical Cancer Research Identifying the Cellular Features and Gene Expression Characteristics Underlying MRI Visibility in … Continue (..)

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Scienmag

JULY 6, 2022

The research reveals new insights into how memories are formed and stored in the brain and could provide scientists with new information about diseases such […].

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BioTech 365

APRIL 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Algorithm maps gene expression in space.As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity.

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BioTech 365

OCTOBER 14, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Protein that manipulates gene expression inside the cell nucleus could inspire new RSV drugs, vaccines.Protein that manipulates gene expression inside the cell nucleus could inspire new RSV … Continue reading →

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BioTech 365

JUNE 28, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells.ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key … Continue reading →

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BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue (..)

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Medical Xpress

NOVEMBER 24, 2022

But they are also involved in regulating the genes expressed within—and the signaling between—cells. When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body.

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Medical Xpress

MARCH 13, 2023

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

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BioTech 365

JANUARY 31, 2022

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: A new method for mapping gene expression deep in the body could one day be used to track stem cells or cancer therapy.Even fans of black-and-white film … Continue reading →

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BioTech 365

DECEMBER 4, 2020

New Research Reveals the Secret Behind a Key Cellular Process (scitechdaily.com) New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now — precisely how … Continue reading → Source : Biology Textbooks Wrong?

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Scienmag

JULY 12, 2021

Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […]. The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell.

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Scienmag

JANUARY 4, 2022

A joint study by two groups of researchers at Peking University revealed for the first time the “pan-cancer single-cell landscape of tumor-infiltrating T cells”. Combining gene expression profiles and T cell receptor sequences, it investigated the heterogeneity and dynamics […].

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Scienmag

DECEMBER 10, 2020

Credit: Nucleic Acids Research Scientists at Tokyo Institute of Technology decipher how to quantitatively assess the effects of specific epigenetic changes on the rate of transcription by developing a mathematical model. Their study published in Nucleic Acids Research provides an accurate quantitative approach […].

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Scienmag

MAY 27, 2021

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function.

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Scienmag

FEBRUARY 18, 2021

Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in Genes & Development on February 18.

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BioTech 365

DECEMBER 11, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How epigenetic switches control gene expression.Scientists at Tokyo Institute of Technology have deciphered how to quantitatively assess the effects of specific epigenetic changes on the rate of … Continue reading → (..)

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Drug Discovery World

OCTOBER 4, 2023

Scientists have discovered the link between gene expression, DNA methylation, and brain structural changes in depression, revealing new potential therapeutic targets. The post Researchers uncover molecular pathways underlying depression appeared first on Drug Discovery World (DDW).

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BioTech 365

APRIL 12, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Understudied mutations have big impact on gene expression.An

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BioTech 365

NOVEMBER 25, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study highlights role of disordered protein interactions in gene expression.A

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Medical Xpress

FEBRUARY 15, 2023

Researchers from the Cardiology Department at the University Medical Center Mainz have now discovered that noise exposure (average sound pressure level 72 dB; peak level 85 dB) up to 4d resulted in pro-inflammatory aortic gene expression in mice.

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Scienmag

MAY 16, 2022

Just as it’s hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell’s environment.

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Medical Xpress

NOVEMBER 21, 2022

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects.

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Medical Xpress

FEBRUARY 10, 2023

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

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Drug Discovery World

APRIL 17, 2024

DDW’s Diana Spencer speaks to Josh Mandel-Brehm , CEO of Massachusetts-based biotech CAMP4, to understand the role regulatory RNAs play in gene expression and how the founders overcame the challenge of launching a business based on brand new science. DS: How easy was it to transfer theoretical research into a viable business?

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Medical Xpress

DECEMBER 13, 2022

If humans are ever going to be able to regrow damaged tissues the way lizards and fish routinely do, it will require the precise control of gene expression in time and place—otherwise you might end up with random cells growing everywhere or a new body part that never quits growing.

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Scienmag

JUNE 14, 2021

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

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Drug Discovery World

NOVEMBER 29, 2022

Using artificial intelligence, researchers at Chalmers University of Technology, Sweden have succeeded in designing synthetic DNA that controls the cells’ protein production. . The AI designs synthetic DNA, where it is easy to modify its regulatory information in the desired direction of gene expression. .

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Drug Discovery World

FEBRUARY 27, 2024

Orchestrating the naturally occurring conductors of gene expression can shift the functional state of cells and alter gene expression. Genetic tuning can impart a wide range of transcriptional changes, from complete silencing to enhanced expression and every range in between.

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Medical Xpress

NOVEMBER 22, 2022

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell Medicine researchers.

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